A5071833490- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Air Quality Monitoring and Forecasting
- Plant-Microbe Interactions and Immunity
- Plant tissue culture and regeneration
- Plant Pathogenic Bacteria Studies
- Cardiac Ischemia and Reperfusion
- Cytokine Signaling Pathways and Interactions
- Environmental and Agricultural Sciences
- Neuropeptides and Animal Physiology
- Inflammasome and immune disorders
- Environmental Changes in China
- Neuroinflammation and Neurodegeneration Mechanisms
- Transplantation: Methods and Outcomes
- Neonatal and fetal brain pathology
- Microbial bioremediation and biosurfactants
- Polysaccharides and Plant Cell Walls
- Mycorrhizal Fungi and Plant Interactions
- Extracellular vesicles in disease
- Music Therapy and Health
- Pediatric Pain Management Techniques
- NF-κB Signaling Pathways
Tianjin University
2021-2024
Shandong Province Meteorological Bureau
2022
China Agricultural University
2017-2021
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2021
Guangzhou First People's Hospital
2013-2020
New York State Office for People With Developmental Disabilities
2019-2020
Guangzhou Medical University
2013-2020
South China University of Technology
2018-2020
Zhujiang Hospital
2016
Southern Medical University
2016
Verticillium wilt is a severe plant disease that causes massive losses in multiple crops. Increasing the resistance to critical challenge worldwide. Here, we report hemibiotrophic dahliae-secreted Asp f2-like protein VDAL leaf wilting when applied cotton leaves vitro but enhances V. dahliae overexpressed Arabidopsis or without affecting growth and development. interacts with E3 ligases U-box 25 (PUB25) PUB26 ubiquitinated by PUBs vitro. However, not degraded PUB25 planta. Besides, pub25...
Circular RNAs (circRNAs) have a regulatory function on inflammation and autophagy, of which rno-circRNA_010705 (circLrp1b) appears to be significantly up-regulated following traumatic brain injury (TBI). Dexmedetomidine (DEX) shows improvement effects in TBI by inhibiting NLRP3/caspase-1. However, whether circLrp1b plays critical roles DEX-mediated attenuation the underlying mechanisms remain unclear. After was established rats controlled cortical impact (CCI) cause trauma, they received an...
The abnormally high nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin containing 3 (NLRP3) inflammasome activity is a typical characteristic of traumatic brain injury (TBI). Dexmedetomidine (Dex) highly selective α-2 adrenergic agonist that inhibits the activation NLRP3. Thus, it was hypothesized Dex could attenuate TBI by inhibiting NLRP3 in hippocampus. Rats were subjected to controlled cortical impact method induce TBI, and treated with Dex. effect treatment on...
Microbial degradation of petroleum hydrocarbons plays a vital role in mitigating contamination and heavy oil extraction. In this study,
Children, after multiple exposures to general anesthesia, appear be at an increased risk of developing learning disabilities. Almost all anesthetics, including sevoflurane that is commonly used for children, are potentially neurotoxic the brain. Anesthesia exposure during development might also associate with behavioral deficiencies later in life. To date, there no treatment prevent anesthesia-induced neurotoxicity and changes. In this study, we anesthetized 7-day-old neonatal mice 3 hrs per...
Sevoflurane and isoflurane are among the most commonly used general anesthetics for children including infants, but their impact on metabolism, especially blood glucose level, in is not well understood. We investigated impacts of anesthesia neonatal (7–8 days old) adult (2–3 months mice with inhalational 2.5% sevoflurane or 1.5% isoflurane, injectable propofol (150 mg/kg) avertin (375 mg/kg), up to 6 hours. found that induced severe hypoglycemia this phenomenon was specific because did...
Currently, the establishment of synthetic microbial consortia with rational strategies has gained extensive attention, becoming one important frontiers biology. Systems biology can offer insights into design and construction consortia. Taking high-efficiency production 2-keto-l-gulonic acid (2-KLG) as an example, we constructed a consortium "Saccharomyces cerevisiae-Ketogulonigenium vulgare" based on systems analysis. In consortium, K. vulgare was 2-KLG producing strain, S. cerevisiae acted...
Atherosclerosis is an inflammatory disease and involves migration of vascular smooth muscle cells (VSMCs). Estrogen inhibits VSMCs migration, while the underlying mechanism remains to be revealed. Recent years, there emerging evidence showing that TNF-related apoptosis-inducing ligand (TRAIL) increases proliferation VSMCs. In this study, we investigated regulatory effect estrogen on TRAIL expression in TNF-α greatly enhanced protein stimulated migration. This was partially inhibited by...
Objective To evaluate the effects of edaravone postconditioning and remote ischemic on myocardial ischemia/reperfusion (I/R) injury in rats.Methods Forty male Sprague-Dawley rats,aged 8 weeks,weighing 250-300 g,were randomly divided into 5 groups (n =8 each):sham operation group (group S); I/R; E); P); EP).Myocardial I/R was induced by occlusion anterior desending branch left coronary artery for 30 min followed 180 reperfusion.Edaravone 3 mg/kg injected intravenously at 1 before reperfusion...
General anesthesia increases the risk for cognitive impairment post operation, especially in children and elderly individuals. To date, there is no treatment to prevent anesthesia-induced neurotoxicity behavioral changes. We administered insulin through intranasal delivery 7-day-old neonatal mice, followed by with sevoflurane 3 hrs per day three consecutive days or once 6 hrs. The mice were then assessed function using open field test, one-trial novel object recognition Morris water maze,...
Four aerosol mass concentration observation stations in Dezhou, Taishan, Weifang and Weihai, which are distributed different regions of Shandong Province, selected to analyze compare their PM2.5 daily, monthly annual changes data: In the daily variation, Weihai all have a bimodal structure, PM data Dezhou same trend with time. each station values show obvious seasonal variation characteristics, higher average winter spring lower summer autumn. The lowest mean four appears August, maximum...
ABSTRACT Verticillium wilt is a severe plant disease that causes massive losses in multiple crops. Increasing the resistance to critical challenge worldwide. Here, we report hemibiotrophic dahliae ( V. )-secreted Asp f2-like protein VDAL leaf wilting when applied cotton leaves vitro, but enhances overexpressed Arabidopsis or without affecting growth and development. interacts with E3 ligases PUB25 PUB26 (PUBs) ubiquitinated by PUBs vitro . However, not degraded planta Besides, pub25 pub26...