- Vitamin C and Antioxidants Research
- Glioma Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Viral-associated cancers and disorders
- Liver Disease Diagnosis and Treatment
- Nanoparticles: synthesis and applications
- Lymphoma Diagnosis and Treatment
- Retinoids in leukemia and cellular processes
- Vitamin D Research Studies
- Radiation Therapy and Dosimetry
- Cancer Risks and Factors
- Pancreatic and Hepatic Oncology Research
- Tissue Engineering and Regenerative Medicine
- Insect behavior and control techniques
- Folate and B Vitamins Research
- Animal and Plant Science Education
- Urban Green Space and Health
- Retinal Diseases and Treatments
- Insect and Pesticide Research
- Platelet Disorders and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Alcohol Consumption and Health Effects
- Mitochondrial Function and Pathology
University of the Pacific
2022
Akron General Medical Center
2019-2021
Cleveland Clinic
2019-2021
University of Iowa Hospitals and Clinics
2019
University of Iowa
2017
Johnson University
2014
Rutgers, The State University of New Jersey
1984-2014
John H. Stroger, Jr. Hospital of Cook County
2009-2013
University of California, Davis
2010
UNSW Sydney
2008
Time between death and discovery of remains, or postmortem interval (PMI), can be assessed using blow fly maggot age. Forensic entomologists rely on published, often nonlocal, species-specific developmental tables to determine In a series common garden experiments, we investigated the rate variation populations Lucilia sericata collected from Sacramento, CA, San Diego, Easton, MA at 16 degrees C, 26 36 C. For C trial time measurement started egg hatch, while for higher temperatures...
Standard treatment for glioblastoma (GBM) includes surgery, radiation therapy (RT), and temozolomide (TMZ), yielding a median overall survival (OS) of approximately 14 months. Preclinical models suggest that pharmacologic ascorbate (P-AscH-) enhances RT/TMZ antitumor effect in GBM. We evaluated the safety adding P-AscH- to standard therapy.This first-in-human trial was divided into an RT phase (concurrent RT/TMZ/P-AscH-) adjuvant (ADJ) (post RT/TMZ/P-AscH- phase). Eight dose cohorts were...
The effects of growth hormone and/or thyroxine treatments on antibody production, primary lymphoid organ development, and general body were examined in two dwarf strains (sex-linked dwarf—SLD, autosomal dwarf—ADW) a normal-growing strain (K) White Leghorn chickens. One-day-old male chicks assigned to experimental groups treated either with (T4) feed supplements or daily mammalian (GH) injections combination these (T4/GH). Within the SLD strain, GH resulted significant enhancement (P < 0.005)...
INTRODUCTION: Obesity increases the risk of pancreatic cancer by up to 50%. Epidemiologic studies indicate that disparities exist in obesity trends across different demographics United States. This is suspected be from modifiable factors, comorbidities, and differences gut microbiome, along with social determinants health such as a lack access high-volume treatment centers. Our aim determine if variation exists demographic obese patients over last 15 years. METHODS: We performed...
The mammalian neocortex is six‐layered brain structure responsible for higher cognitive functions, voluntary motor behavior, and perception. differentiation of neocortical projection neurons into each layer requires an uninterrupted coordination functional gene expression, which may be susceptible to insults like transient intrauterine ischemia (TII). We developed a model TII in anesthetized gravid mouse at E15 15 minutes. Previously conducted cortical layer‐marker studies CDP, transcription...
<p>Supplementary Legend</p>
<p>Supplemental Figure 1: P-AscH- treatment in combination with RT and TMZ decreases the systemic oxidaitive stress marker 4-hydroxy-2-nonenal modified proteins. S1A-SAB.</p>
<p>Supplementary Legend</p>
<div>AbstractPurpose:<p>Standard treatment for glioblastoma (GBM) includes surgery, radiation therapy (RT), and temozolomide (TMZ), yielding a median overall survival (OS) of approximately 14 months. Preclinical models suggest that pharmacologic ascorbate (P-AscH<sup>−</sup>) enhances RT/TMZ antitumor effect in GBM. We evaluated the safety adding P-AscH<sup>−</sup> to standard therapy.</p>Patients Methods:<p>This first-in-human trial was...
<div>AbstractPurpose:<p>Standard treatment for glioblastoma (GBM) includes surgery, radiation therapy (RT), and temozolomide (TMZ), yielding a median overall survival (OS) of approximately 14 months. Preclinical models suggest that pharmacologic ascorbate (P-AscH<sup>−</sup>) enhances RT/TMZ antitumor effect in GBM. We evaluated the safety adding P-AscH<sup>−</sup> to standard therapy.</p>Patients Methods:<p>This first-in-human trial was...
<p>Supplemental Figure 1: P-AscH- treatment in combination with RT and TMZ decreases the systemic oxidaitive stress marker 4-hydroxy-2-nonenal modified proteins. S1A-SAB.</p>
e12523 Background: From 1991 to 2005, the number of cases non-AIDS defining cancers (NADC) rose from 3,192 10,059 in USA. Studies have shown an improvement survival for many HIV-associated malignancies post HAART era. Drug-drug interactions between HIV therapy and chemotherapy (CTX) are not well understood. medications can inhibit or induce cytochrome p450 system, modulating CTX clearance. To understand CTX-HIV medication interactions, we performed a retrospective analysis all patients (pts)...