- Gut microbiota and health
- Probiotics and Fermented Foods
- Mesenchymal stem cell research
- Reproductive tract infections research
- Adipokines, Inflammation, and Metabolic Diseases
- Milk Quality and Mastitis in Dairy Cows
- Food Security and Health in Diverse Populations
- Helicobacter pylori-related gastroenterology studies
- Immune cells in cancer
- Indoor Air Quality and Microbial Exposure
- Food Safety and Hygiene
- Tendon Structure and Treatment
- Periodontal Regeneration and Treatments
- Clostridium difficile and Clostridium perfringens research
- Inflammatory Bowel Disease
- Head and Neck Cancer Studies
- Nutrition, Health and Food Behavior
Yonsei University
2021
Severance Hospital
2021
Seoul National University
2009-2019
<h3>Objective</h3> Metabolic syndrome (MetS) arises from complex interactions between host genetic and environmental factors. Although it is now widely accepted that the gut microbiota plays a crucial role in metabolism, current knowledge on effect of genetics specific microbes related to MetS status remains limited. Here, we investigated links among factors, humans. <h3>Design</h3> We characterised microbial community composition 655 monozygotic (n=306) dizygotic (n=74) twins their families...
Abstract Lactobacillus species are the predominant vaginal microbiota found in healthy women of reproductive age and help to prevent pathogen infection by producing lactic acid, H 2 O anti-microbial compounds. Identification novel isolates that exhibit efficient colonisation secrete anti- Candida factors is a promising strategy vulvovaginal candidiasis. The azole antifungal agents used treat candidiasis elicit adverse effects such as allergic responses drug interactions. strains with...
Background: Although survival of transplanted stem cells in vivo and differentiation into tenocytes vitro have been reported, there no studies demonstrating that mesenchymal (MSCs) could secrete their own proteins as differentiated tenogenic cells. Purpose/Hypothesis: Using a xenogeneic MSC transplantation model, we aimed to investigate whether MSCs differentiate the lineage proteins. The hypothesis was human would be able human-specific rat tendon injury model. Study Design: Controlled...
Exclusive enteral nutrition (EEN) induces remission in pediatric Crohn's disease (CD). The exact mechanism of EEN therapy CD is unknown, but alteration the intestinal microflora after thought to affect mucosal healing. To determine link between and therapeutic efficacy CD, we established a murine model dextran sulfate sodium (DSS)-induced colitis applied therapy.Eight-week-old C57BL/6 mice were administered DSS for 4 days induce colitis, either normal chow (NC) or was following days. grouped...
Lactobacillus jensenii SNUV360 is a potential probiotic strain that shows antimicrobial activity for the treatment of bacterial vaginosis. Here, we present complete genomic sequence L. SNUV360, isolated from vaginal sample healthy Korean woman. Analysis may provide insight into its functional activity.
ABSTRACT Lactobacillus fermentum SNUV175 has been identified as a probiotic strain that inhibits pathogenic microorganisms related to women’s health. We present the complete genomic sequence of L. isolated from vagina South Korean woman. This information may provide insight into functional activity this strain.
Objectives: The aim of this study was to evaluate the occurrence microbiological contamination kitchen utensils and environments food service operations at university located in Seoul, Korea. Methods: We collected swab samples from surfaces knives, chopping boards, floors, drains, as well drinking water airborne bacteria 20 operations. Three bacterial indicators five poisoning were measured quantitatively qualitatively, respectively. used selective culture media PCR assay targeting 16S rRNA...
In this study, we identified different strains of Bifidobacterium isolates from ten set discordant monozygotic twin pairs who has more than 10% differential BMI index and compared their strain‐specific anti‐obesity activities by using high‐fat diet‐induced obesity mouse model. C57BL/6 mice (n=13 per group) were orally administered with human‐derived bifidobacterial mixture (10 9 cfu/mouse, everyday) for 16 weeks. The changes in body weight, visceral fat mass, insulin resistance showed no...