A5101503428- Memory Processes and Influences
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Neonatal Respiratory Health Research
- RNA Interference and Gene Delivery
- Cancer-related gene regulation
- Neurobiology of Language and Bilingualism
- Advanced Drug Delivery Systems
- Ferroptosis and cancer prognosis
- Memory and Neural Mechanisms
- Autophagy in Disease and Therapy
- Respiratory viral infections research
- Advanced Breast Cancer Therapies
- Genomics, phytochemicals, and oxidative stress
- Lung Cancer Treatments and Mutations
- Sirtuins and Resveratrol in Medicine
- Adipose Tissue and Metabolism
- Drug Solubulity and Delivery Systems
- Child and Animal Learning Development
- Cancer Genomics and Diagnostics
- Ocular Surface and Contact Lens
- Neuroendocrine Tumor Research Advances
- Psychological and Educational Research Studies
- Lung Cancer Research Studies
- Neural and Behavioral Psychology Studies
Affiliated Zhongshan Hospital of Dalian University
2021-2024
Peking University
2018-2023
ShenZhen People’s Hospital
2023
Southern University of Science and Technology
2021-2022
Jinan University
2019-2022
Shanghai East Hospital
2020-2021
Tianjin Medical University
2016-2017
Second Hospital of Tianjin Medical University
2016-2017
Abstract Background Ferroptosis is a recently recognized non-apoptotic cell death that distinct from the apoptosis, necroptosis and pyroptosis. Considerable studies have demonstrated ferroptosis involved in biological process of various cancers. However, role esophageal adenocarcinoma (EAC) remains unclear. This study aims to explore ferroptosis-related genes (FRG) expression profiles their prognostic values EAC. Methods The FRG data clinical information were downloaded Cancer Genome Atlas...
Hypertension is characterized by endothelial dysfunction, vascular remodeling, and rearrangement of the extracellular matrix. Besides, pathogenesis hypertension closely related to excess generation reactive oxygen species (ROS). Nicotinamide phosphoribosyltransferase (NAMPT) a rate-limiting enzyme in nicotinamide adenine dinucleotide (NAD) biosynthesis that influences activity NAD-dependent enzymes, such as sirtuins, which possess protein deacetylase cleave NAD during deacetylation cycle....
How memory representations are eventually established and maintained in the brain is one of central issues research. Although hippocampus various regions have been shown to be involved learning memory, how they coordinate support successful through errors unclear. In this study, a retrieval practice (RP) - feedback (FB) paradigm was adopted address issue. Fifty-six participants (27 behavioral group, 29 fMRI group) learned 120 Swahili-Chinese words associations underwent two RP-answer FB...
Abstract Background Several studies have demonstrated autophagy was involved in the process of esophageal adenocarcinoma (EAC). The aim this study to explore autophagy-related genes (ARGs) correlated with overall survival (OS) EAC patients. Methods Expressions ARGs and normal samples were downloaded from TCGA database. GO KEGG enrichment analyses used investigate bioinformatics functions. Univariate multivariate cox regressions performed identify prognostic independent risk factors. ROC...
Previous studies have shown that the ventral medial prefrontal cortex (vmPFC) plays an important role in schema-related memory. However, there is intensive debate to what extent activation of subregions hippocampus involved retrieving In addition, it unclear how functional connectivity (FC) between vmPFC and hippocampus, as well with other regions, are modulated by prior knowledge (PK) during memory retrieval over time. To address these issues, participants learned paragraphs described...
One influential theory on object knowledge is feature-based model, which proposes that the organized by different feature types, such as sensory/perceptual and motor/functional ones. Previous studies have shown prior enhances processes of acquiring remembering relevant information. However, whether effect applied to types conceptual information over time remains unclear. In this study, we addressed question testing memory features at various retention intervals. The level was manipulated...
Non-small cell lung carcinoma (NSCLC) patients who initially received tyrosine kinase inhibitor (TKI) therapy often acquired resistance via multiple complex mechanisms. The amplification of FGF3/4/19/CCND1 on chromosome 11q13 was found in many cancers with TKI resistance. However, the role these amplifications TKI-resistant NSCLC remains uncovered. Here, we generated model lines PC-9 and HCC827. Upregulation strongly promoted proliferation gefitinib cells. To find out potential therapeutic...
Esophageal squamous cell carcinoma (ESCC) is the most common and aggressive tumor worldwide, long-term survival of these patients remains poor. Three databases (GSE17351, GSE20347, GSE100942) were obtained from Gene Expression Omnibus, 193 differentially expressed genes including 56 upregulated 137 downregulated identified by paired test using limma R package. Then, functional enrichments gene ontology Kyoto Encyclopedia Genes Genomes analyses showed mainly related protein digestion...
Background: Lung cancer remains a major global health challenge. Macrophages (Macs) are one important component of tumor microenvironments (TMEs); however, their prognostic relevance to lung is currently unknown due the complexity phenotypes. Methods: In present study, reanalysis and atlas reconstruction downloaded single-cell RNA sequencing (scRNAseq) data were used systematically compare transcriptional changes in Mac subtypes across different stages cancer. Results: We found that with...
Dysfunctional phenotype modulation and calcium channels in airway smooth muscle cells (ASMCs) are important characteristics of remodeling chronic asthma. However, the mechanisms underlying these pathological processes remain unclear. SET (I2PP2A, inhibitor-2 protein phosphatase 2A) has many significant functions is involved various physiological processes. This study aimed to determine function asthma.BALB/c mice were sensitized by ovalbumin injection repeated inhalation ovalbumin. The Penh...
The American Society of Infectious Diseases (IDSA) published the 2009 guidelines for diagnosis and treatment seasonal influenza, prior to H1N1 influenza pandemic.Since then, new rapid molecular diagnostic assays became available, drugs were approved use, many studies in patients with infection have been conducted.In December 2018, IDSA an update guidelines.This document addresses information regarding testing, chemoprophylaxis antiviral medications, issues related institutional outbreak...