Paul Liu

ORCID: 0000-0001-8092-6353
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About
Contact & Profiles
Research Areas
  • Ultrasound Imaging and Elastography
  • Photoacoustic and Ultrasonic Imaging
  • Ultrasonics and Acoustic Wave Propagation
  • Advanced MRI Techniques and Applications
  • Wound Healing and Treatments
  • Advanced Radiotherapy Techniques
  • Reconstructive Surgery and Microvascular Techniques
  • Cardiovascular Health and Disease Prevention
  • Surgical site infection prevention
  • Histone Deacetylase Inhibitors Research
  • Cerebrovascular and Carotid Artery Diseases
  • Image and Signal Denoising Methods
  • Cardiovascular Disease and Adiposity
  • Magnetic properties of thin films
  • Infrared Thermography in Medicine
  • Liver Disease Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Cardiac, Anesthesia and Surgical Outcomes
  • Signaling Pathways in Disease
  • Ultrasound and Hyperthermia Applications
  • Ovarian cancer diagnosis and treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Neural Network Applications
  • Body Contouring and Surgery
  • Flow Measurement and Analysis

Children's Hospital of Orange County
1999-2025

Brown University
2012-2024

The University of Sydney
2018-2024

Creative Commons
2016-2023

Providence College
2010-2023

Rhode Island Hospital
2012-2022

Sichuan University
2019-2021

Chengdu University
2019

Roger Williams Medical Center
2010-2012

Boston University
2011-2012

We have previously shown that the inhibition of histone deacetylases (HDACs) protects heart against acute myocardial ischemia and reperfusion injury. also demonstrated HDAC stimulates myogenesis angiogenesis in a cultured embryonic stem cell model. investigate whether vivo preserves cardiac performance prevents remodeling mouse infarction (MI) through stimulation endogenous regeneration. MI was created by ligation left descending artery. Animals were divided into three groups: 1) sham group,...

10.1124/jpet.111.189910 article EN Journal of Pharmacology and Experimental Therapeutics 2012-01-23

A review of therapeutic effects in preclinical and clinical studies suggests that concordance between large animal (pig=78%), small laboratory (53%) vitro (57%) results with those observed humans is only partial. Pig models wound healing provide major advantages over other models. Since the vast majority wound-healing research done rodents vitro, low rate a significant impediment to will have any impact.To generate clinically relevant experimental data, hypothesis generation should begin, or...

10.1089/wound.2012.0367 article EN Advances in Wound Care 2012-12-18

Abstract Perpendicular magnetic anisotropy (PMA) ferromagnetic CoFeB with dual MgO interfaces is an attractive material system for realizing memory applications that require highly efficient, high speed current-induced switching. Using this structure, a sub-nanometer layer has the potential to simultaneously exhibit switching in accordance conservation of spin angular momentum, and thermal stability owing enhanced interfacial PMA arises from two CoFeB-MgO interfaces. However, difficulty...

10.1038/s41598-019-54466-7 article EN cc-by Scientific Reports 2019-12-19

Ultrasound based estimation of fetal biometry is extensively used to diagnose prenatal abnormalities and monitor growth, for which accurate segmentation the anatomy a crucial prerequisite. Although deep neural network-based models have achieved encouraging results on this task, inevitable distribution shifts in ultrasound images can still result severe performance drop real world deployment scenarios. In article, we propose complete examination system deal with troublesome problem by...

10.1109/jbhi.2023.3298096 article EN IEEE Journal of Biomedical and Health Informatics 2023-07-24

Abstract Vascular endothelial growth factor (VEGF) is a heparin‐binding, dimeric polypeptide with potent mitogenic effects on cells. VEGF expression has also been reported in ovarian epithelial tumors (OETs), which may be associated gonadotropin stimulatioin. We recently that most OETs, including OET cell lines, express receptors. Here we studied mRNA 141 and 35 benign samples using reverse transcriptase polymerase chain reaction situ hybridization (ISH). production by lines under...

10.1002/ijc.1593 article EN International Journal of Cancer 2001-12-13

We and others have demonstrated that HDAC inhibition protects the heart against myocardial injury. It is known Akt-1 MAP kinase play an essential role in modulation of protection cardiac preconditioning. Our recent observations shown was activated post-myocardial infarction following inhibition. However, it remains unknown whether MKK3 are involved inhibition-induced acute ischemia reperfusion sought to investigate genetic disruption eliminate cardioprotection elicited by associated with...

10.1371/journal.pone.0065474 article EN cc-by PLoS ONE 2013-06-10

Abstract Background Giemsa staining of thick blood smears remains the "gold standard" for detecting malaria. However, this method is not very good diagnosing low-level infections. A simultaneous Plasmodium -parasitized culture and both bright field fluorescence was developed its ability to improve detection efficiency tested. Methods total 22 nucleic acid-specific fluorescent dyes were tested their provide easily observable falciparum red cells following staining. Results Of 14 that...

10.1186/1475-2875-6-89 article EN cc-by Malaria Journal 2007-07-06

The recent advent of in-context learning (ICL) capabilities in large pre-trained models has yielded significant advancements the generalization segmentation models. By supplying domain-specific image-mask pairs, ICL model can be effectively guided to produce optimal outcomes, eliminating necessity for fine-tuning or interactive prompting. However, current existing ICL-based exhibit limitations when applied medical datasets with substantial diversity. To address this issue, we propose a dual...

10.1109/tmi.2024.3440311 article EN IEEE Transactions on Medical Imaging 2024-01-01

Scaling STT-MRAM cells beyond 1X technology nodes will require MTJ devices smaller than 30 nm. For such small sizes, process-induced damage becomes a primary factor of device performance. A robust method assessing magnetic properties sub-30 nm is thus needed. Here we report measurements the anisotropy field H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">K</sub> down to 20 using ST-FMR. We show that increases for decreasing sizes. The...

10.1109/iedm.2017.8268516 article EN 2021 IEEE International Electron Devices Meeting (IEDM) 2017-12-01

Surgical treatment of pressure ulcers is challenging for high recurrence rates. Deepithelialized flaps have been used previously with the aim to eliminate shearing forces and cone (COP) effect. The goal this study adopt a standardized protocol evaluate if 2 different flap techniques affect outcomes. novel COP illustrated. Twenty patients were prospectively treated coverage over 36-month period. According type, assigned groups: group 1 11 9 conventional without anchoring technique. We adopted...

10.1097/gox.0000000000001234 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2017-03-01

Abstract Pulsed Wave Doppler (PW) is a traditional ultrasound technique used for the diagnosis of vascular diseases. The conventional diagnostic method mainly based on hemodynamic parameters obtained from PW spectrum. However, it relies clinical observation and medical experience through lots patient data investigation analysis. collected are varied by different equipment, detection regions operation techniques, resulting in image styles, which decreases application generality method. And...

10.1088/1742-6596/1769/1/012009 article EN Journal of Physics Conference Series 2021-01-01

Modern medical ultrasound scanners estimate blood velocity distribution by computing the spectrogram of a temporal data sequence, typically using periodogram methods which require long observation windows. Furthermore, an additional B-mode image is often displayed, resulting in gaps at emissions. We propose data-adaptive estimator for periodically gapped (PG) that extends PG-Capon and PG-APES two dimensional spatial to one spectrum. show through realistic flow simulations our method improves...

10.1109/icassp.2009.4959614 article EN IEEE International Conference on Acoustics Speech and Signal Processing 2009-04-01

Fixed-beam radiotherapy systems with subjects rotating about a longitudinal (horizontal) axis are subject to gravity-induced motion. Limited reports on the degree of this motion, and any deformation, has been reported previously. The purpose study is quantify anatomical motion caused by around axis, using cone-beam CT (CBCT). In current study, purpose-made was aligned Varian TrueBeam kV imaging system. CBCT images three live rabbits were acquired at fixed rotational offsets cradle. Rigid...

10.1088/1361-6560/aabf12 article EN Physics in Medicine and Biology 2018-04-18

Ultrasound elastography is the technique of obtaining tissue stiffness information. In tumor diagnosis, one most important parameters for characterization, more accurate information clinic doctors obtain, reliable diagnosis conclusion they can make. ultrasound elastography, motion tracking between two successive frames plays a key role strain estimation. Many algorithms have been presented recently; however, them are either inefficient real time or not robust general clinical applications....

10.1109/icbbe.2009.5163082 article EN 2009-06-01
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