Jindong Dai

ORCID: 0000-0001-8120-1389
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Renal cell carcinoma treatment
  • Epigenetics and DNA Methylation
  • Phagocytosis and Immune Regulation
  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Urologic and reproductive health conditions
  • Cancer Immunotherapy and Biomarkers
  • Renal and related cancers
  • Cancer-related molecular mechanisms research
  • Ferroptosis and cancer prognosis
  • MRI in cancer diagnosis
  • Computational and Text Analysis Methods
  • Machine Learning in Healthcare
  • Carbon and Quantum Dots Applications
  • Luminescence and Fluorescent Materials
  • Advanced biosensing and bioanalysis techniques
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Brain Tumor Detection and Classification
  • EEG and Brain-Computer Interfaces
  • Bladder and Urothelial Cancer Treatments
  • Radiomics and Machine Learning in Medical Imaging

Sichuan University
2022-2025

West China Hospital of Sichuan University
2022-2025

Jiangsu University
2024

333 Background: The objective of this study is to develop prediction models and provide diagnostic results for prostate biopsy among patients. Methods: This paper presents an improved tree model, called the Light gradient boosting machine building a cancer (PCa) risk model. research data used in (Waves 2008-2022) are obtained from 1987 patients who underwent transperineal at West China Hospital. All had indications (high levels specific antigen (PSA), suspect lesions magnetic resonance...

10.1200/jco.2025.43.5_suppl.333 article EN Journal of Clinical Oncology 2025-02-10

Abstract Intraductal carcinoma of the prostate (IDC-P) is a lethal cancer subtype that generally coexists with invasive high-grade acinar adenocarcinoma (PAC) but exhibits distinct biological features compared concomitant adenocarcinoma. In this study, we performed whole-exome, RNA, and DNA-methylation sequencing IDC-P, concurrent PAC lesions, adjacent normal tissues isolated from 22 radical prostatectomy specimens. Three evolutionary patterns IDC-P were identified: early divergent, late...

10.1158/0008-5472.can-23-1176 article EN Cancer Research 2023-10-17

Abstract Purpose: Fumarate hydratase–deficient renal cell carcinoma (FH-deficient RCC) is a rare and lethal subtype of kidney cancer. However, the optimal treatments molecular correlates benefits for FH-deficient RCC are currently lacking. Experimental Design: A total 91 patients with from 15 medical centers between 2009 2022 were enrolled in this study. Genomic bulk RNA-sequencing (RNA-seq) performed on 88 45 untreated RCCs, respectively. Single-cell RNA-seq was to identify biomarkers...

10.1158/1078-0432.ccr-23-2760 article EN cc-by-nc-nd Clinical Cancer Research 2024-03-21

<div>Abstract<p>Intraductal carcinoma of the prostate (IDC-P) is a lethal cancer subtype that generally coexists with invasive high-grade acinar adenocarcinoma (PAC) but exhibits distinct biological features compared concomitant adenocarcinoma. In this study, we performed whole-exome, RNA, and DNA-methylation sequencing IDC-P, concurrent PAC lesions, adjacent normal tissues isolated from 22 radical prostatectomy specimens. Three evolutionary patterns IDC-P were identified: early...

10.1158/0008-5472.c.7002666.v1 preprint EN 2024-01-02

<div>Abstract<p>Intraductal carcinoma of the prostate (IDC-P) is a lethal cancer subtype that generally coexists with invasive high-grade acinar adenocarcinoma (PAC) but exhibits distinct biological features compared concomitant adenocarcinoma. In this study, we performed whole-exome, RNA, and DNA-methylation sequencing IDC-P, concurrent PAC lesions, adjacent normal tissues isolated from 22 radical prostatectomy specimens. Three evolutionary patterns IDC-P were identified: early...

10.1158/0008-5472.c.7002666 preprint EN 2024-01-02
Coming Soon ...