A5000120363- Food Quality and Safety Studies
- Nutrition, Health and Food Behavior
- Agriculture, Soil, Plant Science
- Phytochemicals and Antioxidant Activities
- Phytoestrogen effects and research
- Natural product bioactivities and synthesis
- Garlic and Onion Studies
- Fermentation and Sensory Analysis
- Ecology and Conservation Studies
- Nutritional Studies and Diet
- Pharmacological Effects of Natural Compounds
- GABA and Rice Research
- Fungal Biology and Applications
- Estrogen and related hormone effects
- NF-κB Signaling Pathways
- Food Drying and Modeling
- Genomics, phytochemicals, and oxidative stress
- Culinary Culture and Tourism
- Sensory Analysis and Statistical Methods
- Postharvest Quality and Shelf Life Management
- Protein Hydrolysis and Bioactive Peptides
- Enzyme Production and Characterization
- Ginseng Biological Effects and Applications
- Food composition and properties
- Phytase and its Applications
Rural Development Administration
2012-2024
Jeonbuk Agricultural Research & Extension Services
2024
National Institute of Agricultural Science and Technology
2015-2023
Instituto de Ciencias Agrarias
2019-2022
Dongshin University
2022
Wonkwang University
2020
National Academy of Agricultural Science
2012-2016
Ewha Womans University
2008-2016
Eulji University
2015
Yong In University
2011
Reactive oxygen species, produced by oxidative stress, initiate and promote many metabolic diseases through activation/suppression of redox-sensitive transcription factors. NF-κB Nrf2 are important regulators oxidation resistance contribute to the pathogenesis diseases. We identified MafK, a novel transcriptional regulator that modulates activity. MafK knockdown reduced activation, whereas overexpression enhanced function. mediated p65 acetylation CBP upon LPS stimulation, thereby...
Recently, considerable attention has been focused on exploring the potential antioxidant properties of plant extracts or isolated products origin. Prunella vulgaris var. lilacina is widely distributed in Korea, Japan, China, and Europe, it continues to be used treat inflammation, eye pain, headache, dizziness. However, reports activities P. are limited, particularly concerning relationship between its phenolic content capacity. In this study, we investigated anticancer an ethanol extract...
BACKGROUND/OBJECTIVES: Although preclinical studies suggest that garlic has potential preventive effects on cardiovascular disease (CVD) risk factors, clinical trials and reports from systematic reviews or meta-analyses present inconsistent results.The contradiction might be attributed to variations in the manufacturing process can markedly influence composition of products.To investigate this issue further, we performed a meta-analysis powder CVD factors.MATERIALS/METHODS: We searched...
Prunella vulgaris var. lilacina, a herbal medicine, has long been used in Korea for the treatment of sore throat, and to alleviate fever accelerate wound healing. Although therapeutic effect P. lilacina is likely associated with anti-inflammatory activity, precise underlying mechanisms are largely unknown. Here, we sought elucidate possible activity. We have investigated activity various solvent fractions (hexane, butanol, chloroform water) from ethanol extract activated macrophages. The...
Luteolin-7-O-glucoside (LUT7G), a flavone subclass of flavonoids, has been found to increase anti-oxidant and anti-inflammatory activity, as well cytotoxic effects. However, the mechanism how LUT7G induces apoptosis regulates cell cycles remains poorly understood. In this study, we examined effects on growth inhibition tumors, cycle arrest, induction ROS generation, involved signaling pathway in human hepatocarcinoma HepG2 cells. The proliferation cells was decreased by dose-dependent...
A rare subpopulation of cancer cells, termed stem cells (CSCs), may be responsible for tumor relapse and resistance to conventional chemotherapy. The development a non-toxic, natural treatment the elimination CSCs is considered strategy with minimal side effects. In present study, potential Sasa quelpaertensis leaf extract (SQE) its two bioactive compounds, tricin p-coumaric acid, exert anti-CSC effects by suppressing stemness characteristics were evaluated in colon cells. CD133+CD44+...
Oxidative stress and inflammation are common to many pathological conditions. Defense mechanisms protect cells from oxidative stress, but can become over-activated following injury inflammation. NF-<TEX>${\kappa}B$</TEX> Nrf2 transcription factors regulate proinflammatory antioxidant gene expression, respectively. Studies have shown that natural dietary compounds Nrf2, preventing stress. Here, we report major of Prunella vulgaris var. lilacina such as rosmarinic acid, oleanolic ursolic acid...
We investigated the antihypertensive effects of Artemisia scoparia (AS) in spontaneously hypertensive rats (SHR). The were fed diets containing 2% (w/w) hot water extracts AS aerial parts for 6 weeks. group had significantly lower systolic and diastolic blood pressure levels than control group. also angiotensin I converting enzyme (ACE) activity II content serum compared to showed higher vascular endothelial growth factor ras homolog gene family member A expression kidney plasma lipid...
본 연구에서는 우리나라의 청양고추를 13개 지역에서 노지재배된 것을 채취하여 재배지역별 품질 특성을 비교 분석하였다. 일반성분의 경우 단백질함량은 12.74~19.98%, 지방함량은 4.54~7.17%, 회분함량은 6.07~9.81% 범위로 넓은 분포를 보였다. 무기성분 함량은 지역별 차이를 보였지만 주요 무기성분은 K이었다. pH 및 총산도는 각각 4.86~5.26 2.10~4.25% 범위였다. 청양고추의 유리당은 fructose glucose가 유리당으로 검출되었고 8.55~17.06% 3.25~10.47% 큰 나타냈다. 색도 중 a값은 28.89~37.12의 범위였고, ASTA값은 76.54~139.57의 a값에 비해 Capsaicin 100.27~261.54 mg%, dihydrocapsaicin 51.01~84.58 mg% 범위였고 capsaicinoid 11개 200 이상의 함량을 연구결과 청양고추는 재배지역에 따른 심한 함량 변이를 나타냈으며, 추후 다양한 품종을...
Postmenopausal women experience estrogen deficiency-related menopausal symptoms (e.g., hot flashes and mood swings) a dramatic increase in the incidence of chronic diseases. Although estrogen-replacement therapy (ERT) can reduce mortality from cardiovascular disease improve osteoporosis symptoms, its side effects have limited recent use. This study investigated estrogen-like activity aqueous extract Agrimonia pilosa Ledeb. The estrogenic A. was by using several vitro assays. binding on...
This study compared aroma compositions and sensory attributes of raw cooked Tenebrio molitor larvae (mealworms). Main mealworms were strong wet-soil-like, less-intense oily, shrimp-like sweet-corn-like. Quantitatively, the major components hydrocarbons aldehydes. As cooking proceeded, sweet-corn-like, roasted, fried-oil-like increasingly perceived with steaming, roasting, frying, respectively. Some pyrazines, pyrrolidines, carbonyls increased or appeared in roasted fried mealworms. Partial...
Rice is the staple food and one of world’s three major grain crops. contains more than 100 bioactive substances including phytic acid, isovitexin, γ-oryzanol, phytosterols, octacosanol, squalene, γ-aminobutyric acid (GABA), tocopherol, tocotrienol derivatives, etc. Out them, γ-oryzanol known to have important biological profile such as anti-oxidants, inhibitor cholesterol oxidation, reduce serum levels in animals, effective treatment inflammatory diseases, inhibit tumor growth, blood...
Excess accumulation of lipids and oxidative stress in the liver contribute to nonalcoholic fatty disease (NAFLD). We hypothesized that Pinus densiflora Sieb. et Zucc. (PSZ) can protect against NAFLD by regulating lipid liver. To investigate effect PSZ upon NAFLD, we used an established cellular model: HepG2 cells treated with oleic acid. Then, extent hepatic steatosis was assessed levels inflammatory markers measured. Oleic acid-treated cells, compared controls, had greater accumulation....
본 연구에서는 다양한 가공공정 처리를 한 더덕 추출물의 총 폴리페놀 및 플라보노이드 함량과 항산화활성 변화를 비교하였다. 함량은 S5FDW에서 73.9 mg GAE/g과 50.9 QUE/g으로 가장 높게 나타났으며, DE에서는 15.7 14.7 낮았다. DPPH와 ABTS radical 소거능은 농도 의존적인 경향을 나타냈으며, 1.0 mg/mL 농도에서 27.0±2.5%, 17.4±0.6%로 S5FEW에서 높은 소거능을 보였다. SOD 유사활성은 HFDE가 29.7±3.2%로 유사활성을 보였으며, DE가 19.9±1.6%로 낮은 활성을 나타내었다. FRAP에 의한 환원력은 S5FDW가 140.8±4.5 μM Fe(Ⅱ)/g으로 환원력을 Fe<SUP>2+</SUP> chelating 활성은 46.0±1.6%로 보였고, 15.8±1.0%로 가공공정을 이용한 항산화 활성 간의 상관관계는 플라보노이드, DPPH 소거능 그리고 r=0.958(p<0.001),...
Nightly fasting duration and meal timing are associated with metabolic disorders. This study aimed to investigate the relationships of nightly type 2 diabetes mellitus (T2DM) using data from 2016–2020 Korea National Health Nutrition Survey. A total 22,685 adults ≥ 19 years were included in this study. was calculated by subtracting interval between day’s first last eating times 24 h. The analyzed various parameters, including episodes percentage energy intake during morning (05:00 9:00 a.m.),...
매운 고추와 맵지 않은 고추를 이용하여 고추장 및 김치용으로 분쇄된 고춧가루의 입도별 분포를 확인하고 이에 따른 색도, ASTA값 캡사이신 함량을 비교분석 하였다. 품종에 관계없이 고추장용 고춧가루에서는 425～300 ㎛의 크기가 가장 많았고 이를 기준으로 입자의 작아지거나 커질수록 그 함량이 적어지는 것으로 나타났다. 김치용 1000 ㎛ 이상의 입도를 가지는 고춧가루가 포함되어 있었으며 고추장용보다 입도분포가 불규칙하게 색은 크기에 따라 색의 차이가 나타나는 것을 확인할 수 있었으며, 작을수록 색도 값(Hunter Lab)이 증가하였다. 역시 높은 값을 보였다. 시료의 capsaicinoids 함량은 전반적으로 작아질수록 증가하여 색도와 ASTA값의 결과와 비슷한 경향을 이러한 물리적 특성은 품질평가 시 중요한 요소로 작용할 있다고 판단되며 보다 다양한 연구가 진행되어야 한다고 생각된다.
본 연구는 참취 에탄올 추출물과 용매분획물의 항산화 활성과 총 폴리페놀 함량 및 플라보노이드 함량을 측정하고, 생리활성과 성분 간의 상관관계를 비교?분석하였다. 함량은 70% 추출물 99.6 mg GAE eq/g으로 나타났으며, ethyl acetate 분획물 141.9 다른 분획물보다 높은 나타내었다(p<0.05). 또한 함량도 분획물에서 105.6 QUE DPPH 라디칼 소거능과 ABTS 소거능의 경우 1,000 μg/mL 농도에서 97.1% 98.7%를 보여 대조군인 ascorbic acid, α-tocopherol BHT와 유사한 소거능을 SOD 유사활성은 42.8%의 활성을 나타내어 DPPH, 소거능보다 비교적 낮은 FRAP에 의한 환원력 측정 결과에서도 그러나 Fe<SUP>2+</SUP> chelating 활성 측정은 chloroform 1,000μg/mL 81.8%로 높게 오히려 분획물에서는 6.2%로 가장 낮게 나타났다(p<0.05). 이상의 결과 용매 중...
Volatile compounds from two South-East Asian fermented soybean foods, Chungkuk-jang (CKJ) and Itohiki-natto (natto), were analysed by gas chromatography-mass spectrometry (GC-MS), chromatography (GC), GC-sniffing. A total of 112 identified. large amount ethanol was detected CKJ, while acetone methyl isobutyrate major components natto. The characteristic odor CKJ some ethyl esters short chain fatty acids, diallyl disulfide, several natto-like identified as ammonia, 2,5-dimethylpyrazine,...
본 연구에서는 염생식물인 칠면초와 세발나물의 인슐린 저항성을 개선하는 효과를 조사하였다. 실험에 사용한 OLETF쥐는 CCK-1 수용체의 결함으로 인해 걸쳐 제 2형 당뇨병이 유발되는데, 저항성이 진행되는 10주령부터 28주령이 될 때까지 세발나물을 18주 동안 섭취시켰다. 염생식물식이군들의 체중이나 공복혈당 변화는 식이기간 전반적으로 대조군과 유의적인 차이를 보이지 않았다. Oral glucose tolerance test에서 염생식물 섭취가 당 내성을 보였으나 그 혈당 변화를 면적으로 환산하였을 때 각 식이군들 간의 차이는 관찰되지 혈중 insulin 및 HbA1c 수치는 유의하게 낮은 수치를 보였으며, adiponectin 높고 leptin과 ghrelin 낮았으나 현저한 세발나물식이군의 중성지질과 총 cholesterol 대조군에 비해 유의적으로 더 낮았다. 지질산화물 함량은 식이군 간 유의차가 않았으나 염생식물식이군에서 경향을...