A5080211712- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Advanced Radiotherapy Techniques
- Phosphodiesterase function and regulation
- Lung Cancer Diagnosis and Treatment
- Statistical Methods in Clinical Trials
- Genital Health and Disease
- Sexual function and dysfunction studies
- Global Cancer Incidence and Screening
- Endometrial and Cervical Cancer Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Bacterial Identification and Susceptibility Testing
- Lung Cancer Treatments and Mutations
- Pancreatic function and diabetes
- Hepatocellular Carcinoma Treatment and Prognosis
- Renin-Angiotensin System Studies
- Economic and Financial Impacts of Cancer
- Metabolism, Diabetes, and Cancer
- Advanced Causal Inference Techniques
- Esophageal Cancer Research and Treatment
- Stock Market Forecasting Methods
- Financial Markets and Investment Strategies
- Chemotherapy-induced cardiotoxicity and mitigation
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Mycobacterium research and diagnosis
All India Institute of Medical Sciences Bhopal
2021-2025
Indian Institute of Science Education and Research, Bhopal
2025
Dignity Health
2024
SRM Institute of Science and Technology
2023
SRM University
2023
Government Medical College
2023
Health and Human Development (2HD) Research Network
2008-2023
Hunter Holmes McGuire VA Medical Center
2019-2022
Narsee Monjee Institute of Management Studies
2021-2022
University of Arizona Cancer Center
2020
Black men are more likely to die of prostate cancer than white men. In with similar stages disease, the contribution biological vs nonbiological differences this observed disparity is unclear.To quantify association black race long-term survival outcomes after controlling for known prognostic variables and access care among cancer.This multiple-cohort study included updated individual patient-level data clinical T1-4N0-1M0 from following 3 cohorts: Surveillance, Epidemiology, End Results...
Purpose Radiation therapy is a critical component in the care of patients with non-small-cell lung cancer (NSCLC), yet cardiac injury after treatment significant concern. Therefore, we wished to elucidate incidence events and their relationship radiation dose heart. Patients Materials Study eligibility criteria included stage II III NSCLC treated on one four prospective trials at two centers from 2004 2013. All were reviewed graded per Common Terminology Criteria for Adverse Events (v4.03)....
Comparative efficacy research performed using population registries can be subject to significant bias. There is an absence of objective data demonstrating factors that sufficiently reduce bias and provide accurate results.MEDLINE was searched from January 2000 October 2016 for observational studies comparing two treatment regimens any diagnosis cancer, SEER, SEER-Medicare, or the National Cancer Database. Reporting quality statistical methods were assessed components STROBE criteria....
Preclinical studies demonstrated that radiation up-regulates PD-L1 expression in tumor cells, providing a rationale for combining PD-1/PD-L1 inhibitors with radiation. However this has not been validated patients non-small cell lung cancer due to the difficulty obtain serial biopsies. Measuring circulating cells (CTCs), may allow real-time monitoring of immune activation tumor. In study, whole blood from non-metastatic NSCLC was collected before, during, and after or chemoradiation using...
Abstract Purpose: Since the identification of PRKAR1A mutations in Carney complex, substitutions and small insertions/deletions have been found ∼70% patients. To date, no germ-line deletion and/or insertion exceeded a few base pairs (up to 15). Although families map chromosome 2, it is possible that current sequencing techniques do not detect larger gene changes PRKAR1A–mutation-negative individuals with complex. Experimental Design: screen for gross alterations gene, we applied Southern...
Abstract Several types of adrenocortical tumors that lead to Cushing syndrome may be caused by aberrant cyclic AMP (cAMP) signaling. We recently identified patients with micronodular hyperplasia who were carriers inactivating mutations in the 2q-located phosphodiesterase 11A (PDE11A) gene. now studied frequency two missense substitutions, R804H and R867G, conserved regions enzyme several sets normal controls, including 745 individuals enrolled a longitudinal cohort study, New York Cancer...
Diagnosis of Tuberculosis (TB) is time-consuming, cumbersome, and expensive. Moreover, there a lack real-time monitoring screening testing as well data management storage. Serological point-of-care tests, which are rapid affordable, have been viewed desirable method for TB diagnosis long time, although they cannot be used to confirm the disease. Three novel antigens Mycobacterium tuberculosis (MTB), causative agent TB, considered colorimetric diagnosis. The immunochromatic flow-through test...
ABSTRACT The objective of this study is to correlate rpoB mutations found on the new-generation sequencing (NGS) in Mycobacterium tuberculosis (MTB) isolates with minimum inhibitory concentrations (MICs) rifampicin (RIF). We assessed for 151 archived clinical MTB that were determined phenotypically susceptible RIF (101; 66.89%), and remaining 50 (50; 33.11%) resistant by BACTEC MGIT SIRE DST. MIC values using colorimetric redox indicator (Resazurin/REMA) method, results correlated gene...
Objective To elucidate the functional erection rate after prostate stereotactic body radiotherapy ( SBRT ) and to develop a comprehensive prognostic model of outcomes treatment. Patients Methods Between 2008 2013, 373 consecutive men with localized cancer were treated at single academic institution as part prospective clinical trial or registry. Prospective longitudinal patient‐reported health‐related quality life HRQ oL) data was collected using Expanded Prostate Cancer Index Composite EPIC...
Abstractpp120 (Ceacam 1) undergoes ligand-stimulated phosphorylation by the insulin receptor, but not insulin-like growth factor 1 receptor (IGF-1R). This differential is regulated C terminus of β-subunit least conserved domain two receptors. In present studies, deletion and site-directed mutagenesis in stably transfected hepatocytes derived from knockout mice (IR−/−) revealed that Tyr1316, which replaced nonphosphorylatable phenylalanine IGF-1R, pp120 receptor. Similarly, nonconserved...
BACKGROUND Stereotactic body radiation therapy (SBRT) for localized prostate cancer involves high‐dose‐per‐fraction treatments. Its use is increasing, but concerns remain about treatment‐related toxicity. The authors assessed the incidence and predictors of a global decline in health‐related quality life (HRQOL) after SBRT. METHODS From 2008 to 2014, 713 consecutive men with received treatment SBRT according prospective institutional protocol. Expanded Prostate Cancer Index Composite...
Abstract To meet the unprecedented requirement of diagnostic testing for SARS-CoV-2, a large number kits were authorized by concerned authorities use within short period time during initial phases ongoing pandemic. We undertook this study to evaluate inter-test agreement and other key operational features 5 such commercial that have been extensively used in India routine COVID-19. The five evaluated, using panel positive negative respiratory samples, considering kit provided National...
Abstract The extent to which PSA screening is related prostate cancer mortality reduction in the United States (US) controversial. US Surveillance, Epidemiology, and End Results Program (SEER) data from 1980 2016 were examined assess relationship between cumulative excess incidence (CEI) era clarify impact of race on this relationship. CEI was considered as a surrogate for intensity with testing subsequent biopsy appropriate. Data 163,982,733 person-years diagnosed 544,058 cancers (9...