A5035533377- Glioma Diagnosis and Treatment
- Cancer Research and Treatments
- Virus-based gene therapy research
- Neuroinflammation and Neurodegeneration Mechanisms
- Immune cells in cancer
- CAR-T cell therapy research
- Biopolymer Synthesis and Applications
- Microtubule and mitosis dynamics
- Cancer, Hypoxia, and Metabolism
- Viral gastroenteritis research and epidemiology
- Mathematical Biology Tumor Growth
- Vascular Tumors and Angiosarcomas
- Cancer Cells and Metastasis
- Cancer Diagnosis and Treatment
Rostov Research Institute of Oncology
2020
e15597 Background: Oncolytic virotherapy is developing intensively in modern oncology. Viruses demonstrate the ability to direct oncolysis and stimulation of antitumor immune activity; this experiment was aimed at solving question prevalence one them. Glial tumors are most common brain tumors; oncolytic viruses show certain prospects their treatment due penetrate blood-brain barrier. The aim study determine possible effect new unclassified group K rotaviruses (RVK) on T98G U87MG glioblastoma...
Glial tumors comprise about 60 % of primary malignant brain tumors, and 70 them show morphological signs high-grade cancer (High Grade Gliomas III , IV WHO 2016) [1, 2]. Despite a significant technical pre- intraoperative progress as well advances in radiotherapy chemotherapy, the overall median survival is very low, being less than 20 months [3] 12 patients with relapse [4]. Recent studies have shown that chemo- radioresistance due to existence stem cells [5, 6]. Poor treatment outcomes...
2545 Background: The standard treatment of malignant brain gliomas, including surgical and radiation therapies, does not provide recovery a long-time favorable prognosis. development technologies international guidelines on the introduction electric (TTF) electromagnetic (TMS) fields in combination for glioblastomas aims to improve immediate results, as shown experiments human glioblastoma cell culture. TMS protocol requires further refinement parameters frequency, intensity, exposure with...
ПРЕДИКТОРНАЯ РОЛЬ ЛОКАЛЬНОГО УРОВНЯ ЦИТОКИНОВ В ТЕЧЕНИИ НИЗКОДИФФЕРЕНЦИРОВАННЫХ ГЛИАЛЬНЫХ ОПУХОЛЕЙЗлатник Е.Ю
ГБ-глиобластома КСФ -колониестимулирующий фактор ТЭЛА
e14515 Background: The choice of cell source for 3D bioprinting in vivo-like models glial tumors is crucial and must take into account the ability to proliferation stable metabolism. Oral administration 5-aminolevulinic acid (5-ALA) patients prior surgery increases fluorescent contrast between tumor surrounding tissue, but effect agents on cells vitro unknown. aim study was obtaining viable tissues using 5-ALA, as well development a primary culture bioprinting. Methods: Tumor tissue obtained...
СОЗДАНИЕ ОРТОТОПИЧЕСКОЙ И ГЕТЕРОТОПИЧЕСКОЙ МОДЕЛИ ОПУХОЛЕВОГО РОСТА ГЛИОМЫ ЧЕЛОВЕКА Шульгина О.Г. 1 , Сагакянц А.Б. Межевова И.В. Лукбанова Е.А. Заикина Е.В. Непомнящая Е.М. Игнатов С