- Nutritional Studies and Diet
- Fatty Acid Research and Health
- Nutrition and Health in Aging
- Diet and metabolism studies
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Infant Nutrition and Health
- Bone health and osteoporosis research
- Metabolomics and Mass Spectrometry Studies
- Nutrition, Genetics, and Disease
- Gut microbiota and health
- Adipokines, Inflammation, and Metabolic Diseases
- Obesity, Physical Activity, Diet
- Body Composition Measurement Techniques
- Breastfeeding Practices and Influences
- Child Nutrition and Water Access
- Machine Learning in Healthcare
- Vitamin D Research Studies
- Phytoestrogen effects and research
- Pregnancy and preeclampsia studies
- Consumer Attitudes and Food Labeling
- Muscle metabolism and nutrition
- Bioactive Compounds in Plants
- Cholesterol and Lipid Metabolism
- Heavy Metal Exposure and Toxicity
Southern Medical University
2016-2025
University of Oxford
2023-2024
Instituto de Nutricion e Higiene de los Alimentos
2023
Jiangsu University of Science and Technology
2021-2022
Bridge University
2022
Sun Yat-sen University
2012-2022
Nantong University
2021
University of Iowa
2020
Nanjing University of Aeronautics and Astronautics
2020
Purpose Butyrate, a short-chain fatty acid derived from dietary fiber, inhibits proliferation and induces cell death in colorectal cancer cells. However, clinical trials have shown mixed results regarding the anti-tumor activities of butyrate. We previously that sodium butyrate increases endoplasmic reticulum stress by altering intracellular calcium levels, well-known autophagy trigger. Here, we investigated whether butyrate-induced mediated autophagy, there was crosstalk between apoptotic...
The application of face detection and recognition technology in security monitoring systems has made a huge contribution to public security. Face is an essential first step many analysis systems. In complex scenes, the accuracy would be limited because missing false small faces, due image quality, scale, light, other factors. this paper, two-level model called SR-YOLOv5 proposed address some problems dense faces actual scenarios. research optimized backbone loss function YOLOv5, which aimed...
Pro-inflammatory diet interacting with gut microbiome might trigger for Crohn's disease (CD). We aimed to investigate the relationship between dietary inflammatory potential and microflora/metabolites change their link CD.The was assessed using a index (DII) based on Food Frequency Questionnaire from 150 new-onset CD patients 285 healthy controls (HCs). selected 41 89 HCs who had not received medication metagenomic targeted metabolomic sequencing profile microbial composition as well fecal...
Abstract Background The temporal relationship between adiposity and gut microbiota was unexplored. Whether some microbes lie in the pathways from to insulin resistance is less clear. Our study aims reveal investigate whether may mediate association of with a longitudinal human cohort study. Methods We obtained repeated-measured shotgun metagenomic anthropometric data 426 Chinese participants over ~3 years follow-up. Cross-lagged path analysis used examine BMI microbial features. associations...
Background: The Guangzhou Nutrition and Health Study (GNHS) aims to assess the determinants of metabolic disease in nutritional aspects, as well other environmental genetic factors, explore possible biomarkers mechanisms with multi-omics integration.
Abstract Objective Previous studies showed an inconsistent association of fruit and vegetable consumption with bone health. We assessed the associations in Chinese adolescents, young postmenopausal women. Design A cross-sectional study conducted China during July 2009 to May 2010. Setting Bone mineral density (BMD) content (BMC) at whole body, lumbar spine left hip were measured dual-energy X-ray absorptiometry. Dietary intakes using FFQ. All these values separately standardized into Z...
Scope To compare the effects of supplementary eicosapentaenoic acid (EPA)+docosahexaenoic (DHA) versus α‐linolenic (ALA) on lipid profiles, inflammatory status, and fatty composition peripheral blood mononuclear cells (PBMCs) in hypercholesterolemic adults. Methods results A randomized, controlled, double‐blind trial is conducted to examine consumption control oil, 4.2 g/d ALA, 7.2 1.8 DHA+EPA, or 3.6 EPA+DHA for 12 weeks PBMCs vitro production interleukin‐6 (IL‐6) tumor necrosis factor‐α...
Former evidence regarding reference values of abdominal fat percentage (AFP) and optimal anthropometric indicators in predicting obesity measured by dual-energy X-ray absorptiometry (DXA) scan Chinese children were scarce. A total 452 aged 6–9 years included this cross-sectional study. Abdominal lean mass a DXA scan, AFP calculated. Anthropometric including body index (BMI), chest circumference (CC), waist (WC) hip (HC) measured, waist-to-hip ratio (WHR), waist-to-height (WHtR) was also By...
Diabetes mellitus is a major chronic disease that results in readmissions due to poor control. Here we established and compared machine learning (ML)-based readmission prediction methods predict risks of diabetic patients.The dataset analyzed this study was acquired from the Health Facts Database, which includes over 100,000 records patients 1999 2008. The basic data distribution characteristics were summarized then analyzed. In study, 30-days defined as period less than 30 days. After...
We aimed to investigate whether the gut microbiota and fecal short-chain fatty acids (SCFAs) are associated with skeletal muscle mass strength in healthy Chinese children aged 6-9 years. In this study, 412 were enrolled. 16S rRNA gene sequencing was used characterize compositions. Fecal SCFAs quantified using high-performance liquid chromatography. Dual X-ray absorptiometry measure total body lean soft tissue (TSM), fat (TBF), appendicular (ASM), (AFM). TSM/height2 (TSMI), ASM/height2...
Evidence from animal models supports a link between short-chain fatty acids (SCFAs), key subset of gut microbial metabolites, and autism spectrum disorders (ASD). However, findings human studies on this topic are unclear. We aimed to investigate whether fecal SCFAs associated with ASD in Chinese children aged 6-9 years old. A total 45 90 sex- age-matched neurotypical controls were enrolled. High-performance liquid chromatography was applied quantify 10 SCFA subtypes feces. Dietary other...
Scope Alcoholic liver disease (ALD) is a global public health concern. Nobiletin, polymethoxyflavone abundant in citrus fruits, enhances circadian rhythms and ameliorates diet‐induced hepatic steatosis, but its influences on ALD are unknown. This study investigates the role of brain muscle Arnt‐like protein‐1 ( Bmal1 ), key regulator clock, nobiletin‐alleviated ALD. Methods results uses chronic ethanol feeding plus an binge to establish models flox/flox liver‐specific knockout LKO) mice....
The dietary inflammatory index (DII®) is a measure of the overall potential person's diet. However, there have been no studies looking at effect DII on measures muscle mass and strength. We aimed to examine association between skeletal strength in Chinese children.A total 466 children aged 6-9 years completed study. Total body (TSM), appendicular (ASM) lean (ALM) were determined using Dual-energy X-ray absorptiometry. TSM/Height², TSM/Weight, ASM/Height² ASM/Weight calculated. residual...
Although obesity is considered osteoprotective, the effects of body fat and distribution on bone tissue after adjusting for weight remain uncertain. This study evaluated relationships between mass, distribution, mineral status beyond its weight-bearing effect. We recruited 466 children aged 6-10 years in China. Dual-energy X-ray absorptiometry was used to determine density (BMD) content (BMC) total less head (TBLH), as well mass (FM) percentage (%FM) segmental body. Weight-adjusted measures...
Plant oil for cooking typically provides 40% to 50% of dietary fat, 65% linoleic acid, 44% α-linolenic acid and 41% oleic in the Chinese diet.
The aim of the study was to investigate how maternal dietary patterns and maternal/fetal cytokines are associated with birth weight whether mediate association. A total 469 pregnant women their children were recruited for this prospective study. Dietary in pregnancy identified using factor analysis data from three consecutive 24 h recalls. Maternal umbilical blood serum (adiponectin (APN), IL-6 interferon-γ) measured via ELISA. Path used explore relationships between diet, weight. Four...