Lei Gong

ORCID: 0000-0001-8430-2329
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About
Contact & Profiles
Research Areas
  • Viral Infections and Vectors
  • SARS-CoV-2 and COVID-19 Research
  • Influenza Virus Research Studies
  • COVID-19 Clinical Research Studies
  • Viral gastroenteritis research and epidemiology
  • Vector-Borne Animal Diseases
  • SARS-CoV-2 detection and testing
  • Viral Infections and Outbreaks Research
  • Animal Disease Management and Epidemiology
  • Fire effects on ecosystems
  • Respiratory viral infections research
  • COVID-19 epidemiological studies
  • Data-Driven Disease Surveillance
  • Mosquito-borne diseases and control
  • Hepatitis B Virus Studies
  • Mine drainage and remediation techniques
  • CO2 Sequestration and Geologic Interactions
  • Intracranial Aneurysms: Treatment and Complications
  • Clay minerals and soil interactions
  • interferon and immune responses
  • Acute Ischemic Stroke Management
  • Geological and Geochemical Analysis
  • Pregnancy and preeclampsia studies
  • Gestational Diabetes Research and Management
  • Methane Hydrates and Related Phenomena

Anhui Provincial Center for Disease Control and Prevention
2016-2025

Qingdao Eighth People's Hospital
2024

Indiana University Bloomington
2019-2024

Anhui Medical University
2010-2024

Health Commission of Anhui Province
2024

Zunyi Medical University
2013-2023

Loma Linda University
2017-2023

Yangzhou University
2020

Guangdong Provincial People's Hospital
2019

Guangdong Academy of Medical Sciences
2019

Rationale:The incidence of gestational diabetes mellitus (GDM) is increasing worldwide.However, whether and how GDM exposure induces fetal programming adult cardiac dysfunctional phenotype, especially the underlying epigenetic molecular mechanisms theranostics remain unclear.To address this problem, we developed a late rat model.Methods: Pregnant rats were made diabetic on day 12 gestation by streptozotocin (STZ).Experiments conducted in 6 weeks old offspring.Results: There significant...

10.7150/ijbs.33044 article EN cc-by-nc International Journal of Biological Sciences 2019-01-01

The genusAnaplasma contains seven recognized bacterial species, mainly transmitted by tick bites. two A. phagocytophilum and capra, are known commonly to cause diseases in humans.Anaplasma bovis was initially thought be only an animal agent until the first patient case reported 2019. This study investigated another patients who became sick within one month same township were infected with Anhui Province.This suggested that more bovis-infected may exist this area anaplasmosis require early...

10.46234/ccdcw2022.053 article EN China CDC Weekly 2022-01-01

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease discovered in the 21st century. Human-to-human transmission of has been documented, but mechanisms require further investigation. Epidemiological investigations and genetic analyses patients were conducted, a retrospective cohort study was performed to analyze potential risk factors for person-to-person transmission. According epidemiologic investigations, 14 secondary cases had clear history...

10.1186/s12985-025-02665-2 article EN cc-by-nc-nd Virology Journal 2025-03-12

Knowledge of the clinical progress severe fever with thrombocytopenia syndrome (SFTS) and associated predictors mortality is important for providing appropriate treatment in cases. A multihospital retrospective study was conducted three SFTS-endemic cities, 2018. Of 208 SFTS-confirmed cases, there were 189 survivors 19 deaths. The median age 64 years; 104 (50.0%) patients men, 188 (90.4%) farmers. Furthermore, 203 (97.6%) reported 70 (33.7%) fatigue. Most fatal cases had complications...

10.4269/ajtmh.20-0270 article EN American Journal of Tropical Medicine and Hygiene 2021-02-16

Rare Earth Elements (REE) phosphates (monazite, xenotime, and rhabdophane) are critical REE-bearing minerals typically formed in hydrothermal magmatic ore deposits. The thermodynamic properties of those REE crucial to understanding the solubility, speciation, transport complexes. However, standard-state Gibbs free energy formation (∆G°f) values reported for these literature vary by up 25 kJ mol−1. Here, we present linear relationships that allow evaluation estimation ∆G°f at °C 1 bar three...

10.3390/min14030305 article EN Minerals 2024-03-14

Objective: To understand the epidemiological characteristics of cases COVID-19 epidemic clusters, and explore influence family factors social such as group activities on spread disease. Methods: The data clusters from 19 January, 2020 to 25 February, were collected official platforms 36 cities in 6 provinces China. Descriptive statistical methods, χ(2) test curve fitting used analyze clustered cases. Results: By 2020, 1 052 366 collected. In these cases, 86.9%(914/1 050) occurred families....

10.3760/cma.j.cn112338-20200301-00223 article EN Zhonghua liuxingbingxue zazhi 2020-03-26

Background: In recent years, the increasing number of empty-nest elderly has become a significant global social problem, and rapid development medical technology information improved feasibility telenursing. However, few studies have been conducted on needs telenursing among elderly. The aim this study is to explore for community-dwelling who are completely independent in activities daily living (ADL), or mildly disabled, provide reference improving remote care quality. Methods: A...

10.1089/tmj.2020.0037 article EN Telemedicine Journal and e-Health 2020-06-03

J Oral Pathol Med (2012) 41 : 728–735 Background: The aim of this study was to verify the validity IL‐21 local suppression in submandibular glands preventing development Sjögren’s syndrome non‐obese diabetic (NOD) mice and figure out mechanism. Methods: levels were suppressed by ductal cannulation shRNA lentivirus. Then, saliva flow rates (SFR) histopathologic changes measured assess severity disease development. Real‐time PCR, cytometry, immunohistochemistry used detect T helper cells...

10.1111/j.1600-0714.2012.01175.x article EN Journal of Oral Pathology and Medicine 2012-05-29

Infectious diarrhea cases have increased during the past years in Anhui Province of China, but little is known about its spatial cluster pattern and associated socioeconomic factors. We obtained county-level total infectious 105 counties 2016 computed age-adjusted rates. Socioeconomic factors were collected from Statistical Yearbook. Hot spot analysis was used to identify hot cold for incidence. then applied binary logistic regression models determine association between or clustering risk....

10.4269/ajtmh.19-0161 article EN American Journal of Tropical Medicine and Hygiene 2019-07-23

Cognitive deficits are a devastating neurological outcome seen in survivors of cardiac arrest. We previously reported water electrolysis derived 67% hydrogen gas inhalation has some beneficial effects on short-term outcomes rat model global brain hypoxia-ischemia induced by asphyxia In the present study, we further investigated its protective long-term spatial learning memory function using same animal model. Water was either administered 1 hour prior to arrest for and at 1-hour...

10.4103/2045-9912.266986 article EN Medical Gas Research 2019-01-01

Abstract We compared complete genome sequences of two strains an avian influenza A (H5N6) virus isolated from a patient in Anhui Province with those other GenBank and Global initiative on sharing all data (GISAID). The HA gene the shared homology that A/chicken/Zhejiang/727155/2014 at level similarity 98%. six internal genes were close to H9N2 viruses Zhejiang, Shandong, Guangdong provinces, 99%. In addition, between antigens (NP MP) H5N6 H7N9 H10N8 was Based phylogenetic analysis, belonged...

10.1038/s41598-018-33356-4 article EN cc-by Scientific Reports 2018-10-10

We sought to assess reporting in China's Pneumonia of Unknown Etiology (PUE) passive surveillance system for emerging respiratory infections and identify ways improve the PUE system's detection public health significance. From February 29–May 29, 2016, we actively identified enrolled patients two hospitals with acute (ARI) that met all case criteria. reviewed medical records documented exposure history associated infectious diseases, collected throat samples were tested seasonal avian...

10.1186/s12879-019-4345-0 article EN cc-by BMC Infectious Diseases 2019-09-03

Influenza-like illness (ILI) is one of the most important public health problems globally, causing an enormous disease burden. Influenza infections are common cause ILI. Bacterial and virus co-infection yet data with influenza A B viruses scarce. To identify epidemiological patterns in Anhui province, China, we analyzed surveillance 5 years from 2009 to 2014 collected by Chinese National influenzas network. The results showed that weekly ratio ILI was 3.96 ± 1.9% (95% CI 3.73–4.2%)...

10.3389/fpubh.2022.825645 article EN cc-by Frontiers in Public Health 2022-02-24
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