Xiaolan Xu

ORCID: 0000-0001-8476-3643
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About
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Research Areas
  • Fungal Biology and Applications
  • Plant biochemistry and biosynthesis
  • Radical Photochemical Reactions
  • Catalytic C–H Functionalization Methods
  • Fluorine in Organic Chemistry
  • Bee Products Chemical Analysis
  • Mycorrhizal Fungi and Plant Interactions
  • Cancer-related molecular mechanisms research
  • Insect and Pesticide Research
  • Genomics and Phylogenetic Studies
  • Essential Oils and Antimicrobial Activity
  • Phytochemical compounds biological activities
  • Quinazolinone synthesis and applications
  • Circular RNAs in diseases
  • Cancer Research and Treatments
  • Chemical Synthesis and Reactions
  • Biocrusts and Microbial Ecology
  • Sulfur-Based Synthesis Techniques
  • Plant and Fungal Species Descriptions
  • Turtle Biology and Conservation
  • Nanomaterials for catalytic reactions
  • MicroRNA in disease regulation
  • Plant Diversity and Evolution
  • Inorganic Fluorides and Related Compounds
  • Asymmetric Hydrogenation and Catalysis

Fujian Agriculture and Forestry University
2019-2025

Anhui Medical University
2011-2024

Huazhong Agricultural University
2020-2023

Wuhan University
2023

Northern Jiangsu People's Hospital
2021

Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2020

Henan University of Technology
2019

Hefei University of Technology
2013-2017

Hefei University
2016

Anhui University
2014

The complete chloroplast (cp) genome of Lonicera japonica, a common ornamental and medicinal plant in North America East Asia, was sequenced analyzed. length the L. japonica cp is 155,078 bp, contains pair inverted repeat regions (IRa IRb), 23,774 bp each, as well large (LSC, 88,858 bp) small (SSC, 18,672 single-copy regions. A total 129 genes were identified genome, 16 which duplicated within IR Relative to other genomes, had unique rearrangement between trnI-CAU trnN-GUU. In cpDNA, rps19,...

10.3390/molecules22020249 article EN cc-by Molecules 2017-02-07

Background Lonicera japonica Thunb. is a plant used in traditional Chinese medicine known for its anti-inflammatory, anti-oxidative, anti-carcinogenic, and antiviral pharmacological properties. The major active secondary metabolites of this are chlorogenic acid (CGA) luteoloside. While the biosynthetic pathways these relatively well known, genetic information available species, especially ingredients, limited. Methodology/Principal Findings We obtained one million reads (average length 400...

10.1371/journal.pone.0062922 article EN cc-by PLoS ONE 2013-04-25

Ganoderma lucidum is a traditional Chinese medicinal fungus, and ganoderma triterpenoids (GTs) are one of the main bioactive compounds. These compounds have various pharmacological functions, including anti-tumor, antioxidant, anti-inflammatory, liver-protective, immune-regulating effects. However, manner in which they accumulate, their biosynthesis mechanisms remain unclear. To screen for genes that involved biosynthetic pathway GTs, this study analyzed differential metabolites...

10.3390/jof11010057 article EN cc-by Journal of Fungi 2025-01-13

Propolis has a very complex composition, with antibacterial, anti-inflammatory and other properties. To determine the composition of ethanol extracts Brazilian green propolis (EEP-B) their protective effect on mouse aortic endothelial cells (MAECs), chemical EEP-B was analysed by UPLC/Q-TOF-MS/MS, proliferation lipopolysaccharide (LPS)-induced MAECs determined Cell Counting Kit-8 (CCK-8) assays. The protein levels inflammatory cytokines tumour necrosis factor-α (TNF-α) interleukin- 6 (IL-6)...

10.3390/molecules25204612 article EN cc-by Molecules 2020-10-10

The DNA barcoding technology uses a standard region of sequence for species identification and discovery. At present, "DNA barcode" actually refers to sequences, which are not amenable information storage, recognition, retrieval. Our aim is identify the best symbology that can represent barcode sequences in practical applications. A comprehensive set five markers ITS2, rbcL, matK, psbA-trnH, CO1 was used as test data. Fifty-three different types one-dimensional ten two-dimensional...

10.1371/journal.pone.0035146 article EN cc-by PLoS ONE 2012-05-04

In recent few decades, magnetic nanoparticles have emerged as an ideal support for catalysts because of their easy preparation and functionalization, low toxicity price. Magnetic nanoparticles-supported been used to catalyze lots organic reactions, including C–C bond form reaction, hydrogenation oxidation phase–transfer reaction dihydroxylation reaction. They can be recovered easily by external magnet reused several times with sustained activities. this review, the application magnetite...

10.2174/1385272811317100006 article EN Current Organic Chemistry 2013-05-01

The chemical compositions of ethanol extracts propolis from China (EEP-C) and the United States (EEP-A) their antifungal activity against Penicillium notatum were determined. result showed that a total 49 compounds detected by UPLC-Q-TOF-MS, 30 which present in samples two regions. major EEP-C EEP-A similar, including pinocembrin, pinobanksin-3-O-acetate, galanin, chrysin, pinobanksin, pinobanksin-methyl ether, both them P. with same minimum inhibitory concentration (MIC) value 0.8 mg·mL-1....

10.3390/molecules24193576 article EN cc-by Molecules 2019-10-04

A decarboxylation of alkyl carboxylic acids for alkylfluorination alkene was developed, with the catalysis silver(I) and Selectfluor as both oxidant fluorine source. This reaction is highly chemoselective, producing decarboxylative products rather than competitive fluorination aliphatic acids. practical transformation proceeds efficiently in aqueous media at room temperature exhibits a large range functional-group tolerance various primary secondary carboxylates alkenes.

10.1021/acs.orglett.9b03381 article EN Organic Letters 2019-10-08

The Liangzi Lake Basin (LLB) is an important ecological buffer for Wuhan’s urban agglomeration. It involves the security of middle reaches Yangtze River. Historical land misuse has altered topography and impacted ecosystem services value (ESV). Amid urbanization, it vital to highlight changing use methods their effects on ESV valuation, understanding underlying drivers comprehensively. research centered LLB as its designated study region, utilizes remote sensing satellite data spanning from...

10.3390/su152215763 article EN Sustainability 2023-11-09

A mild and environmentally electrochemical method for the synthesis of quinazolines quinazolinones has been developed through anodic oxidation decarboxylative α-oxocarboxylic acids. The present reaction was efficiently conducted by using simple cheap NH4I as N-source electrolyte in an undivided cell. desired products, quinazolinones, were isolated high yield under chemical oxidant free conditions.

10.1039/d4ra01318b article EN cc-by-nc RSC Advances 2024-01-01

Chinese caterpillar fungus (Ophiocordyceps sinensis) has been widely used as tonic in Asian medicine. Considering its curative effect and high cost, various counterfeit versions of O. sinensis have introduced are commercially available. These counterfeits morphological characteristics that difficult to distinguish based on morphology alone, thereby causing confusion threatening safe use. In this study, internal transcribed spacer (ITS) sequences a DNA barcode were analyzed assessed for rapid...

10.1111/1574-6968.12233 article EN FEMS Microbiology Letters 2013-08-01

A general and effective method for the synthesis of amides through decarboxylative amidation α-keto acids with amines has been developed. The reaction proceeded smoothly to afford corresponding amide products in good yield under air shows excellent functional group tolerance. In addition, protocol can be further applied heterocyclic compounds like benzimidazoles.

10.1039/c6ob01963c article EN Organic & Biomolecular Chemistry 2016-01-01

Gastric cancer (GC) is common in East Asia, yet its molecular and pathogenic mechanisms remain unclear. Circular RNAs (circRNAs) are differentially expressed GC may be promising biomarkers. Here, we investigated the role regulatory mechanism of circTMC5 GC.CircTMC5 expression was detected human adjacent tissues using microarray assays qRT-PCR, while clinicopathological characteristics patients with were used to assess diagnostic prognostic value. The circTMC5/miR-361-3p/RABL6 axis examined...

10.1007/s10120-021-01220-6 article EN cc-by Gastric Cancer 2021-07-22

We developed an electrochemical trifluoromethylation of thiophenols without the use metal catalysts and oxidants. This reaction features mild conditions, readily available substrate, as well moderate to good yields. In addition, this protocol can be easily scaled up with efficiency.

10.1021/acs.joc.0c02659 article EN The Journal of Organic Chemistry 2021-01-08

An efficient method for Cu‐catalyzed decarboxylative trifluoromethylation of β ‐ketoacids to achieve α ‐trifluoromethyl ketones was developed. A wide variety synthetically useful were obtained in modest good yields under mild reaction conditions. The present also exhibits functional‐group compatibility.

10.1002/cjoc.201700271 article EN Chinese Journal of Chemistry 2017-07-12

As the main byproduct of cotton fiber, seed yields about 1.6 times that with its oil rich in unsaturated fatty acids, mainly linoleic acid. It is desirable for breeders to increase content cottonseed without affecting yield and quality fiber. In this study, a seed-specific promoter- (alpha-globulin gene promoter-) driven GhDGAT1 overexpression vector (PαGlob-GhDGAT1) was constructed used transform an upland line YZ1 (Gossypium hirsutum). Overexpression seeds increased total from 4.7% 13.9%...

10.1016/j.cj.2020.10.003 article EN cc-by-nc-nd The Crop Journal 2020-11-26

A simple and efficient method is reported for the synthesis of α-acyloxyketones in moderate to excellent yields from carboxylic acids ketones via electrochemical oxidative C(sp 3 )–H/O–H cross-coupling under metal- oxidant-free conditions.

10.1039/d3qo00204g article EN Organic Chemistry Frontiers 2023-01-01

Wolfiporia cocos (F. A. Wolf) has been praised as a food delicacy and medicine for centuries in China. Here, we present the genome transcriptome of Chinese strain CGMCC5.78 W. cocos. High-confidence functional prediction was made 9277 genes among 10,908 total predicted gene models genome. Up to 2838 differentially expressed (DEGs) were identified be related sclerotial development by comparing transcriptomes mycelial tissues. These DEGs are involved mating processes, differentiation fruiting...

10.1016/j.gpb.2019.01.007 article EN cc-by Genomics Proteomics & Bioinformatics 2020-08-01

Although conventional hybrid breeding has paved the way for improving cotton production and other properties, it is undoubtedly time labor consuming, while cultivation of male sterile line can fix problem. Here, we induced mutants by simultaneously editing three EXCESS MICROSPOROCYTES1 (GhEMS1) genes CRISPR/Cas9. Notably, GhEMS1 are homologous to AtEMS1 genes, which inhibit middle layer tapetum cells as well, leading sterility in cotton. Interestingly, there necrosis-like dark spots on...

10.3389/fpls.2022.1102196 article EN cc-by Frontiers in Plant Science 2023-01-09
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