A5103273325- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Chronic Kidney Disease and Diabetes
- Gout, Hyperuricemia, Uric Acid
- Adipokines, Inflammation, and Metabolic Diseases
- Alcohol Consumption and Health Effects
- Birth, Development, and Health
- Inflammatory Biomarkers in Disease Prognosis
- Acute Kidney Injury Research
- Metabolism and Genetic Disorders
- Case Reports on Hematomas
- Lipid metabolism and disorders
- Blood Pressure and Hypertension Studies
- Renal Diseases and Glomerulopathies
- Nutrition and Health in Aging
- Cancer, Lipids, and Metabolism
- Cytomegalovirus and herpesvirus research
- Dialysis and Renal Disease Management
- Anesthesia and Neurotoxicity Research
- Lipoproteins and Cardiovascular Health
- Blood properties and coagulation
- Bariatric Surgery and Outcomes
- Cardiac Ischemia and Reperfusion
- Renal Transplantation Outcomes and Treatments
- Atherosclerosis and Cardiovascular Diseases
Third Affiliated Hospital of Southern Medical University
2014-2024
Kowloon Hospital
2022
Suzhou Kowloon Hospital
2022
Southern Medical University
2013-2014
Wenzhou Medical University
2013
First Affiliated Hospital of Wenzhou Medical University
2013
Zhangzhou Municipal Hospital of Fujian Province
2013
Metabolic syndrome (MetS), which is a global public health problem, state of chronic low-grade inflammation. This study looked at the changes in hematological parameters and predictive value lymphocyte to high-density lipoprotein cholesterol (HDL-C) ratio (LHR) as new index subjects with without MetS coastal cities southern China.In this cross-sectional study, there were 852 participants (n = 598 n 254 MetS). was defined accordance National Cholesterol Education Program, Adult Treatment...
Objective: To explore the relationship between serum uric acid (SUA) and metabolic syndrome (MS) in men, premenopausal women postmenopausal women. Methods: A cross-sectional study was conducted 1,834 community-based Southern Chinese participants from June to October 2012. Sex-specific SUA quartiles were used as follows: <345, 345–<400, 400–<468, ≥468 µmol/L males; <248, 248–<288, 288–<328, ≥328 females. MS defined by National Cholesterol Education Program Adult Treatment...
Aim To explore the association of lipid ratios and triglyceride (TG) with insulin resistance (IR) in a Chinese population. We also provide clinical utility to identify men women IR. Methods This cross-sectional study included 614 1055 without diabetes. Insulin was defined by homeostatic model assessment IR > 2.69. Lipid TG/ high density lipoprotein cholesterol (HDL-C), total (TC)/HDL-C low (LDL-C)/HDL –C. Logistic regression models accurate estimates area under receiver operating...
Oxidative stress plays a critical role in the pathophysiology of contrast-induced nephropathy (CIN). Since specific treatment CIN remains an unmet medical need, it is imperative to find effective strategy against clinical management CIN. The transcription factor Nrf2 known regulate antioxidative response. aim present study was assess effects tert -butylhydroquinone (t-BHQ), activator Nrf2, prevention and elucidate underlying mechanism its action vitro vivo . We established rat model treated...
ObjectiveTo the best of our knowledge, association insulin resistance (IR) with chronic kidney disease (CKD) has not been well studied in normal-weight individuals. The aim this study is to examine whether IR associated CKD non-diabetic subjects normal weight. We also presence obesity modifies CKD. MethodsData were drawn from a cross-sectional survey China. Both estimated glomerular filtration rate and urinary albumin creatinine ratio used as markers Logistic regression models quartiles...
Hyperuricemia is an independent risk factor for renal damage and can promote the progression of chronic kidney disease (CKD). In present study, we employ a rat model to investigate effects rosiglitazone (RGTZ), peroxisome proliferator-activated receptor-gamma agonist, on development hyperuricemic nephropathy (HN), elucidate mechanisms involved.An HN was established by oral administration mixture adenine potassium oxonate daily 3 weeks. Twenty-four rats were divided into 4 groups: sham...
Metabolic syndrome (MetS), characterized by a constellation of insulin resistance, central obesity, hypertension, and hyperlipidemia, is global health threat. High-sensitivity C-reactive protein (hs-CRP) has been shown to be associated with type 2 diabetes cardiovascular disease; however, its association incident MetS less known. Therefore, the aim this study was examine prospective between hs-CRP among Chinese population in 5-year follow-up study.The levels were measured using serum samples...
<b><i>Objective: </i></b>Previous studies have shown that central obesity is associated with chronic kidney disease (CKD). We hypothesized the association of CKD modified by presence inflammation. To test this hypothesis, we performed study. <b><i>Methods: </i></b>This was a cross-sectional study in southern China. Waist-to-height ratio (WHtR) used as index and C-reactive protein (CRP) an for defined estimated glomerular filtration rate(eGFR)...
Objective To examine the relationship between HW phenotype and risk for CKD in a community population aged 40 years older. Methods A cross-sectional study was conducted Zhuhai from June to October 2012. The participants were divided into three groups: Group 1, Waist circumference >90 cm men or >85 women triglycerides ≥2 mmol/l; 3, ≤90 ≤85 <2 2, remaining participants. prevalence of subgroups determined. association then analyzed using SPSS (version 13.0). Results After adjusting age sex, 1...
Aim: To examine the association of serum lipids, lipid ratios with Chronic Kidney Disease (CKD) in a Chinese population. Methods: Data were drawn from cross-sectional survey China. CKD was defined as estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73m2 or albuminuria-to-creatinine ratio (ACR) > 30 mg/g. Multivariable logistic regressions and multivariate regression models used. Serum lipids included total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C),...
To investigate the correlation between visceral obesity and pathogenesis of chronic kidney disease (CKD) among non-diabetic individuals, to evaluate potential adiposity index (VAI) as a predictor CKD.From December 2017 March 2018, 1877 participants (male n=699, female n=1208) in southern China were recruited for cross-sectional survey. Males females divided into four groups according gender-specific quartiles VAI scores. A logistic regression model was established analyze CKD.Visceral...
High-density lipoprotein (HDL) particles comprising heterogeneous subclasses of different functions exert anti-inflammatory effects by interacting with immune-response cells. However, the relationship HDL cells in metabolic unhealth/obesity has not been defined clearly. The purpose this study was to delineate relational changes immune and inflammatory markers understand role subclasses. A total 316 participants were classified health. detected microfluidic chip electrophoresis. White blood...
To explore the relationship between metabolic syndrome (MS) and risk for chronic kidney disease (CKD) in a Southern Chinese population.A cross-sectional study was conducted 1724 community-based participants from June to October 2012. The prevalence of MS (as defined by International Diabetes Federation) CKD (defined as an estimated glomerular filtration rate <60 mL/min per 1.73 m(2) and/or albuminuria) determined. association then analyzed using STATA software.Metabolic significantly...
Objective: To assess the high-sensitivity C-reactive protein (hs-CRP) levels and explore risk factors for an elevated hs-CRP level. We also provide clinical utility of CRP to identify subjects with metabolic syndrome (MetS). Methods: Data were drawn from a cross-sectional survey in China. Subjects divided into three subgroups: ≤ 1 mg/L, mg/L < 3 > mg/L. Multiple linear regressions logistic regression models used. Results: In Chinese population, 50.43% had low level, 30.21% intermediate...
To determine the optimal cut-off values and evaluate associations of product triacylglycerol glucose (TyG), lipid accumulation (LAPI), visceral adiposity index (VAI) with chronic kidney diseases (CKD) stratified by sex.From January to April 2018, our team had conducted a large-scale cross-sectional survey that contained 2720 individuals on southern coast China. Logistic regression analysis receiver operating characteristic (ROC) analyses were used value TyG, LAPI, VAI for predicting CKD.A...
To investigate the correlation between metabolic syndrome components and chronic kidney disease (CKD) among a community population aged 40 years older in Southern China.From December 2017 to March 2018, 1969 participants (male n = 715, female 1254) were recruited China for cross-sectional survey. A logistic regression model was established analyze CKD.Among subjects, 407 (20.7%) CKD patients, including 152 males (prevalence rate 21.3%) 255 females 20.3%). Anthropometric data (waist...
The purpose of this study was to investigate the association and mediation pathways among muscle mass, function (muscle strength physical performance), malnutrition with depressive symptoms clusters in older hemodialysis patients.
Background The prevalence of chronic kidney disease (CKD) and prediabetes has increased in China, at different rates locations. Therefore a community-based screening research was conducted order to determine the CKD prediabetes, analyze associated risk factors city Southern China. Methods Atotal 7801 community residents aged 18 year older from 6 communities were screened by stratified random cluster sampling method. An estimated glomerular filtration rate (eGFR), albuminuria, fasting plasma...
There is no general consensus on possible factors associated with microalbuminuria in hypertensive patients nor any reported study about this issue Chinese patients. To examine issues, 944 were enrolled a based cross-sectional survey conducted Southern China. Multivariate regression analyses performed to identify the related presence of and urinary excretion albumin. The prevalence non-diabetic 17.16% 15.25%, respectively. Body mass index (BMI), but not waist circumference (WC),...
Aim: To validate the association between visceral obesity and pathogenesis of chronic kidney disease (CKD) among individuals aged 40 years above, potential adiposity index (VAI) to predict CKD. Methods: This study was based on a cross-sectional epidemiologic in People’s Republic China. A total 1,581 residents over were included divided into four groups VAI quartile intervals, namely, Groups I, II, III, IV (eg, Group I patients with their VAIs lowest quartile). Logistic regression analysis...