A5085364264- Salmonella and Campylobacter epidemiology
- Animal Nutrition and Physiology
- Viral gastroenteritis research and epidemiology
- Aquaculture disease management and microbiota
- Livestock and Poultry Management
- Animal Virus Infections Studies
- Bacteriophages and microbial interactions
- Microbial infections and disease research
- Food Safety and Hygiene
- Probiotics and Fermented Foods
- Listeria monocytogenes in Food Safety
- Vibrio bacteria research studies
- Essential Oils and Antimicrobial Activity
- Antibiotic Resistance in Bacteria
- Meat and Animal Product Quality
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial biofilms and quorum sensing
- Advanced Nanomaterials in Catalysis
- Toxoplasma gondii Research Studies
- Trace Elements in Health
- Aquaculture Nutrition and Growth
- Nanoparticles: synthesis and applications
- Veterinary Pharmacology and Anesthesia
- Milk Quality and Mastitis in Dairy Cows
- Lipid Membrane Structure and Behavior
Universidade Federal de Uberlândia
2016-2025
Universidade Federal do Triângulo Mineiro
2022
Weatherford College
2022
Universidade Presidente Antônio Carlos
2013-2015
Universidade de Uberaba
2013-2014
Austral University of Chile
2014
Institute of Biomedical Science
2011
AVM Faculdade Integrada
2009
Ukrainian Free University
2007
Introduction Next-generation sequencing (NGS) has played a pivotal role in the advancement of taxonomics, allowing for accurate identification, differentiation, and reclassification several bacteria species. Bacillus velezensis is Gram-positive, facultatively aerobic, spore-forming bacterium known its antimicrobial antifungal properties. Strains this species are highly relevant agriculture, biotechnology, food industry, biomedicine. Methods In study, we characterized genomes nine strains...
Despite being considered fragile and fastidious, Campylobacter jejuni is the most prevalent cause of foodborne bacterial gastroenteritis, chicken meat main vehicle transmission to humans. This agent can survive adverse conditions in form biofilms, but extreme stress (nutritional, oxidative thermal) promotes acquisition a state called viable not culturable (VBNC). The emergence this pathogen worldwide recent international requirements its control instigated us qualitatively quantitatively...
The poultry industry faces significant challenges in controlling Salmonella contamination while reducing antibiotic use, particularly with the emergence of Heidelberg (SH) strains posing risks to food safety and public health. Probiotics, notably lactic acid bacteria (LAB) Saccharomyces boulardii (SB) offer promising alternatives for mitigating colonization broilers. Understanding efficacy probiotics combating SH their impact on gut health metabolism is crucial improving production practices...
This study aimed to evaluate the virulence characteristics of 55 Campylobacter jejuni strains isolated from chicken carcasses. These included antibiotic resistance, presence genes, and transcription changes after inoculation Caco-2 cells phylogenetic relationship between strains. Resistance amoxicillin norfloxacin was observed in 34/55–61.8% 26/55–47.3% respectively, resistance tetracycline also (18/55–32.7%). The genes flaA, pldA, cadF, ciaB CDT complex were detected 41/55 (74.5%), 35/55...
The aim of the study was to evaluate genotypic and phenotypic characteristics 20 strains S. Heidelberg ( S H) isolated from broilers produced in southern Brazil. similarity presence genetic determinants linked virulence, antimicrobial resistance, biofilm formation, silico -predicted metabolic interactions revealed this serovar as a threat public health. ompC , invA sodC avrA lpfA agfA genes detected 100% luxS gene 70% them. None carries bla SHV mcr-1, qnrA, qnrB qnrS genes. All showed...
Phospholipases A2 (PLA2) represent a superfamily of enzymes widely distributed in living organisms, with broad spectrum pharmacological activities and therapeutic potential. Anti-angiogenic strategies have become one the main tools fighting cancer. In this sense, present work reports inhibition tumor angiogenesis induced by Asp-49 BthTX-II using vitro, ex vivo approaches. We demonstrate that BthTx-II inhibited cell adhesion, proliferation, migration human umbilical vein endothelial cells...
Lately, the bacterial multidrug resistance has been a reason to public health concerning around world. The development of new pharmacology therapies against infections caused by multidrug-resistant bacteria is urgent. In this work, we developed 10 NLC formulations composed essential oils (EO), vegetable butter and surfactant. were evaluated for long-term thermal cycling stability studies in terms (particle size, polydispersion index Zeta potential). vitro antimicrobial assays performed using...
Plant extracts are increasingly recognized as potential prophylactic agents in poultry production due to their diverse bioactive properties. This study investigated the phytochemical and biological properties of Libidibia ferrea (L. ferrea), a plant species native Caatinga region northeastern Brazil. The aim this was identify secondary metabolites demonstrate antimicrobial, antioxidant protective effects extract. Three were produced: EHMV, hydroalcoholic extract from maceration pods, EEMC...
is a virulent Gram-negative bacterial genus mainly found in the intestines of poultry. The indiscriminate use traditional antibiotics has led to drug resistance these pathogens, necessitating development more efficient and less toxic therapies. Despite their complex biologically active structures, clinical applications essential oils (EOs) remain limited. Therefore, this study aimed increase bioavailability, stability, biocompatibility decrease photodegradation toxicity EO using...
The excellence of modern broiler production is based on the genetic improvement strains for high growth rate and egg production, associated with technological developments in nutrition, management, health. Over last decades, clinical biochemistry broilers has been studied to determine serum biochemical component values; however, there are still many knowledge gaps factors that changes these values. In this study, lipid protein profiles 4-week-old male female Cobb breeders were evaluated....
Salmonella spp. is an important foodborne agent of salmonellosis, whose sources in humans often include products avian origin. The control this bacterium difficult especially when spp organized into biofilms. We hypothesized that the novel nanocomposites ZnO nanocrystals doped with silver (Ag) and oxide (Ag2O) (ZnO:Ag-AgO) synthesized by coprecipitation method could or prevent formation Enteritidis (SE) Heidelberg (SH) biofilm its entry turkey eggs. diffraction characteristics Ag2O showed...
This work describes the development of a gastroresistant antimicrobial formulation composed two carriers, pectin and liposomes, intended to improve efficiency norfloxacin (NOR) against multi-resistant bacterial strains. The formulations showed physicochemical stability for 180 days (4 °C) in terms size, polydispersity, zeta potential vesicles, prolonging vitro release NOR 11 h. hybrid nanocarriers improved activity different multidrug-resistant strains, such as Salmonella sp.,...
Campylobacter jejuni (CJ) is the most prevalent zoonotic pathogen of chicken meat and related products, which may lead to gastroenteritis autoimmune diseases in humans. Although controlling this bacterium important, CJ strains resistance against traditional antibiotic therapy has been increased. Vegetable oils fats are natural biomaterials explored since Ancient times, due their therapeutic properties. Nanotechnology promoted miniaturization materials, improving bioavailability efficacy,...
Erysipelothrix sp. isolates obtained from a deadly outbreak in farmed turkeys were sequenced and compared to representatives of the genus. Phylogenetic trees-supported by digital DNA:DNA hybridization Average Nucleotide Identity-revealed novel monophyletic clade comprising pigs, turkeys, fish, including previously described as E. Strain 2. Genes coding for SpaC protein, typically found 2, detected all clade. Therefore, we confirm 2 represents unique species that may be isolated broad host...
To improve the understanding of implications Campylobacterspp. infections in pets and children different environments were analysed 160 faecal samples from 120 (103 dogs 17 cats). Campylobacter spp. detected 6.87% 18.3% cats. From 33 stool positive for spp., 57.6% identified as C. jejuni, 33.4% coli. More than 50% isolates resistant to ceftiofur, sulphazotrim, norfloxacin tetracycline. In humans, most amoxicillin, cefazolin, erythromycin norfloxacin. 19 11 5 contained two four virulence...