A5001116105- Gut microbiota and health
- Probiotics and Fermented Foods
- Clostridium difficile and Clostridium perfringens research
- Epigenetics and DNA Methylation
- Immune Cell Function and Interaction
- Genomics and Phylogenetic Studies
- Sexual Differentiation and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Viral-associated cancers and disorders
- Modular Robots and Swarm Intelligence
- Robotics and Sensor-Based Localization
- Studies on Chitinases and Chitosanases
- Microwave Dielectric Ceramics Synthesis
- Antenna Design and Analysis
- MXene and MAX Phase Materials
- Ultrasound and Cavitation Phenomena
- Microbial Metabolites in Food Biotechnology
- Hydrogen's biological and therapeutic effects
- Millimeter-Wave Propagation and Modeling
- HER2/EGFR in Cancer Research
- Robotic Locomotion and Control
- Intracranial Aneurysms: Treatment and Complications
- Hormonal and reproductive studies
- Urinary Tract Infections Management
- Mycobacterium research and diagnosis
Berry Oncology (China)
2024-2025
Institute of Microbiology
2020-2023
Chinese Academy of Sciences
2009-2023
Microbiology Institute of Shaanxi
2021-2023
Sun Yat-sen University
2021-2023
Sun Yat-sen University Cancer Center
2021-2023
PLA Army Engineering University
2022
Czech Academy of Sciences, Institute of Microbiology
2020-2021
Zhejiang Ocean University
2016-2020
Zhejiang University
2016-2020
Abstract Background In gut microbiome studies, the cultured microbial resource plays essential roles, such as helping to unravel functions and host-microbe interactions. Although several major studies have been performed elucidate human microbiota, up 70% of Unified Human Gastrointestinal Genome species not date. Large-scale isolation identification well availability public are imperative for further characterizing functions. Results this study, we constructed a Gut Microbial Biobank (hGMB;...
Abstract Mice are widely used as experimental models for gut microbiome (GM) studies, yet the majority of mouse GM members remain uncharacterized. Here, we report construction a microbial biobank (mGMB) that contains 126 species, represented by 244 strains have been deposited in China General Microorganism Culture Collection. We sequence and phenotypically characterize 77 potential new species propose their nomenclatures. The mGMB includes 22 17 significantly enriched ob/ob wild-type...
Non-human primates harbour diverse microbiomes in their guts. As a part of the China Microbiome Initiatives, we cultivated and characterized gut microbiome cynomolgus monkeys (Macaca fascicularis). In this report, communicate characterization taxonomy eight bacterial strains that were obtained from faecal samples captive monkeys. The results revealed they represented novel species. proposed names species are Alkaliphilus flagellatus (type strain MSJ-5T=CGMCC 1.45007T=KCTC 15974T),...
The human gastrointestinal tract is inhabited by various microorganisms, including thousands of bacterial taxa that have yet to be cultured and characterized. In this report, we describe the isolation, cultivation, genotypic phenotypic characterization taxonomy five novel anaerobic strains were recovered during massive cultivation isolation gut microbes from faecal samples. On basis polyphasic taxonomic results, propose two genera species. They are Acidaminococcus hominis sp. nov. (type...
A strictly anaerobic, motile bacterium, designated as strain NSJ-9T, was isolated from human faeces. Cells were Gram-negative, non-spore-forming, non-pigmented, and spiral-shaped or slightly curved rods with flagella. Optimal growth in M2GSC medium observed at 37 °C (growth range 30-45 °C) pH 6.5-7.0 6.5-7.5) under anaerobic conditions. Phylogenetic analysis of the 16S rRNA gene revealed that NSJ-9T formed a distinct phylogenetic lineage reflects new genus family Lachnospiraceae, high levels...
Harmful algae blooms (HAB) in eutrophic lakes and rivers have become serious water quality problems that are difficult to eliminate using common methods. Previous research has demonstrated powerful ultrasound can somewhat control cyanobacteria HABs; however, effective energy-efficient settings for ultrasonic parameters not yet been rigorously determined. The results of this study showed the effect removal was enhanced with frequencies, densities, radiation durations 20–90 kHz, 0.0005–0.1...
Abstract Human leukocyte antigen (HLA) molecules are essential for presenting Epstein−Barr virus (EBV) antigens and closely related to nasopharyngeal carcinoma (NPC). This study aims systematically investigate the association between HLA‐bound EBV peptides NPC risk through in silico HLA‐peptide binding prediction. A total of 455 patients 463 healthy individuals endemic areas were recruited, HLA‐target sequencing was performed. prediction EBV, followed by peptidome‐wide logistic regression...
Impact statement Nonhuman primates (NHPs) such as monkeys are the closest living relatives to humans and best available models for causative studies of human health diseases. Gut microbiomes intensively involved in host health. In this study, by large‐scale cultivation microbes from fecal samples monkeys, we obtained previously uncultured bacterial species constructed a Macaca fascicularis Microbial Biobank (MfGMB). The MfGMB consisted 250 strains that represent 97 63 genera, 25 families, 4...
Abstract Background The cultivated gut microbial resource plays essential role in microbiome studies such as function and their interactions with host. Though several major had been performed to understand the cultured human microbiota, up 70% of Unified Human Gastrointestinal Genome species remain uncultivated taxonomy is not clear. Large-scale isolation identification access pubic are imperative for understanding functions. Results Here, we report construction an Gut Microbial Biobank...
Abstract Background Nasopharyngeal carcinoma (NPC), an Epstein–Barr virus (EBV) associated cancer, exhibits extremely high incidence in southern Chinese. Given that human leukocyte antigen (HLA) plays critical roles presentation and relates to NPC susceptibility, it is speculated certain HLA variants may affect EBV reactivation, which a key pathogenic factor of NPC. Therefore, we attempted identify alleles with the indicator Zta‐IgA, healthy males from endemic area. Methods 1078 China...
A MgAl 2 O 4 (MA) spinel layer was synthesized on Ti 3 AlC substrate through the molten salt synthesis (MSS) method. The immersed in MgCl ·6H powders and treated at 800°, 850°, 900°C for h air. continuous 10‐μm‐thick obtained 900°C, by which surface hardness of can be effectively improved. combined scanning electron microscopy observations crystal morphology simulation further revealed that as‐formed presents tetragonal bipyramids with (400)‐orientation.
This paper presents the mechanical design and experimental research of a water strider inspired robot, which are six-legged creatures that move on by propelling themselves using two stroke legs supporting with four other legs. As surface tension is too less for robot to carry heavy facilities, hollow ellipsoids made acrylonitrile-butadiene-styrene copolymer (ABS) were used Instead screw propeller, rowing legs, just like what does, would have infection in great advantage finish meticulous...
Abstract BackgroundThe cultivated gut microbial resource plays essential roles in microbiome studies such as unraveling functions and host-microbe interactions. Though several major have been performed to understand the cultured human microbiota, up 70% of Unified Human Gastrointestinal Genome species remain uncultivated. Large-scale isolation identification their access public are imperative for further understanding functions.ResultsHere, we report construction a Gut Microbial Biobank...
A dual frequency shared-aperture antenna array with grating lobe suppression in millimeter wave (mmW) band is investigated this letter. It consists of a patch working at 2.34 GHz the fundamental TM10 mode and slotted substrate integrated waveguide (SIW) cavity-backed 28.5 element excited TE440 cavity mode. The ground mmW slot employed as radiation microwave band, so high aperture reuse efficiency can be realized. By using staggered distribution technique, serious high-order SIW large spacing...
ABSTRACT Background High sequence homology between CYP21A2 and CYP21A1P poses challenges to genetic diagnosis of congenital adrenal hyperplasia (CAH) due 21‐hydroxylase deficiency (21‐OHD). Traditional testing is unable provide an accurate the complexity CAH. Methods Deletions, duplications, recombination breakpoints were precisely identified by long‐read sequencing (LRS). Results This study presented a pregnant woman, 21‐OHD carrier detected MLPA, her husband, normal subject also MLPA. The...
The clinical diagnosis of Fabry Disease (FD) can be challenging due to the heterogeneity, especially in females. Patients with FD often experience a prolonged interval between onset symptoms and receiving diagnosis. Genetic testing is gold standard for precise FD, however conventional genetic could miss deep intronic variants large deletions or duplications. Although next-generation sequencing, which analyzes numerous genes, has been successfully used detect complex variants, an effective...
Objective To evaluate the prognostic value of three different staging system based on positive lymph nodes,lymph node ratio and log odds nodes in breast carcinoma.Methods In 472 carcinoma patients,survival analysis was performed with Kaplan-Merier COX regression model,the hazard (HR) were compared.Results When more than 10 dissected operation,there statistical differences survival among systems (P ＜ 0.05),while prognosis highly homologous between stage N0 N1.Univariate showed age,tumor...
Objective To evaluate the therapeutic effect of intravenous magnesium sulfate (MgSO4) infusion combined with urokinase (UK) and determine optimal dose for treatment acute cerebral infarction (ACI). Methods One hundred patients AC1 were randomized into 0, 10, 20 mL group control (n=24, 24, 28), former 3 groups received loading or 25% MgSO4 in addition to OK treatment. After initial MgSO4, 60 within 24 h, followed by a daily 14 consecutive days. The blood pressure, tendon reflex, serum...
Abstract Non-human primates harbor diverse microbiomes in their guts. As a part of China Microbiome Initiatives, we cultivated and characterized the gut microbiome cynomolgus monkeys ( Macaca fascicularis ). In this report, communicate characterization taxonomy 8 bacterial strains that were obtained from fecal samples captive monkeys. The results revealed they represented novel species. proposed names species are Alkaliphilus flagellate (type strain MSJ-5 T =CGMCC 1.45007 =KCTC 15974 ),...