Yue Yao

ORCID: 0000-0001-8523-5156
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About
Contact & Profiles
Research Areas
  • Low-power high-performance VLSI design
  • Radiation Effects in Electronics
  • Endometriosis Research and Treatment
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Reproductive System and Pregnancy
  • Embedded Systems Design Techniques
  • Cancer, Hypoxia, and Metabolism
  • Cancer-related molecular mechanisms research
  • Autism Spectrum Disorder Research
  • Advancements in Semiconductor Devices and Circuit Design
  • VLSI and Analog Circuit Testing
  • Distributed systems and fault tolerance
  • Endometrial and Cervical Cancer Treatments
  • Histone Deacetylase Inhibitors Research
  • VLSI and FPGA Design Techniques
  • Diabetes Treatment and Management
  • Formal Methods in Verification
  • Genetics and Neurodevelopmental Disorders
  • Immune cells in cancer
  • Ubiquitin and proteasome pathways

Carnegie Mellon University
2012-2025

Renji Hospital
2021-2022

Shanghai Jiao Tong University
2017-2022

Anhui Medical University
2022

Institute of Neurobiology
2014

Endometrial decidualization is a prerequisite for implantation, and impaired associated with recurrent implantation failure (RIF). Coding genes of the HOX family have been clarified as critical regulators in endometrial decidualization, but role long non-coding RNAs (lncRNAs) gene has yet to be determined. The aim this study was clarify possible roles lncRNAs decidualization. In study, we identified that HOXA11-AS most reduced lncRNA human endometrium during window it elevated RIF patients....

10.1016/j.ymthe.2022.01.036 article EN cc-by-nc-nd Molecular Therapy 2022-01-31

Significance There are no treatments for congenital intellectual disabilities. Here we show that newly discovered timing rules maximizing hippocampal long-term potentiation predict training regimens offset defects in synaptic chemistry and memory the fragile X mental retardation 1 ( Fmr1 ) KO model of syndrome. Wild-type mice required far less to form stable memories when given three trials separated by hour as opposed one extended session; shorter or longer intervals were ineffective. The...

10.1073/pnas.1413335111 article EN Proceedings of the National Academy of Sciences 2014-11-10

Many of today’s message-passing systems not only require messages to be exchanged in a certain order but also happen at time or within window . Such correctness conditions are particularly prominent Internet Things (IoT) and real-time applications, which interface with hardware devices that come inherent timing constraints. Verifying compliance such the intended timed protocol is challenged by their heterogeneity —ruling out any verification method relies on system implemented one common...

10.1145/3704895 article EN Proceedings of the ACM on Programming Languages 2025-01-07

Insulin resistance (IR) contributes to ovarian dysfunctions in polycystic syndrome (PCOS) patients. Serum amyloid A1 (SAA1) is an acute phase protein produced primarily by the liver response inflammation. In addition its role inflammation, SAA1 may participate IR development peripheral tissues. Yet, expressional regulation of ovary and pathogenesis PCOS remain elusive.Follicular fluid, granulosa cells venous blood were collected from non-PCOS patients with without measure abundance for...

10.1186/s12958-021-00873-3 article EN cc-by Reproductive Biology and Endocrinology 2022-01-03

Approximate computing is an emerging design paradigm targeting at error-tolerant applications. The area, delay, and power consumption of a circuit can be improved by sacrificing reasonable amount accuracy. logic synthesis (ALS) aims automatically synthesizing approximate for given target circuit. In this paper, we propose to function maximally disjoint bi-decomposable function, which significantly reduce the implementation cost. We novel techniques effectively generate such approximation...

10.1109/iccd.2017.90 article EN 2017-11-01

Approximate computing is an emerging paradigm for error-tolerant applications. By introducing a reasonable amount of inaccuracy, both the area and delay circuit can be reduced significantly. To synthesize approximate circuits automatically, many logic synthesis (ALS) algorithms have been proposed. However, they mainly focus on reduction are not optimal in reducing circuits. In this paper, we propose DALS, delay-driven ALS framework. DALS works AND-inverter graph (AIG) representation circuit....

10.1145/3240765.3240790 article EN 2018-11-05

Cancer is associated with metabolic changes from increased cell proliferation and growth. Compared to normal differentiated cells, MM cells use the glycolytic pathway even when adequate oxygen present triggering "Glutamine addiction".To investigate single combined effects of epigallocatechin-3-gallate (EGCG) telaglenastat, a glutaminase inhibitor, on apoptosis multiple myeloma line KM3/BTZ.KM3/BTZ were treated different concentrations telaglenastat EGCG alone or in combination their effect...

10.2174/1871520622666220905142338 article EN Anti-Cancer Agents in Medicinal Chemistry 2022-09-06

Glucagon-like peptide-1(GLP-1)as a new treatment of type 2 diabetes, not only has hypoglycemic effect, but also plays an important role in the regulation lipid metabolism. GLP-1 unique regulating metabolism via absorption and transport, fat formation decomposition, hepatic metabolism, cholesterol transport. (Chin J Endocrinol Metab, 2015, 31: 558-560) Key words: Glucagon-like peptide-1; Lipid metabolism; Apolipoproteins

10.3760/cma.j.issn.1000-6699.2015.06.022 article EN 2015-06-25

Abstract Background : Insulin resistance (IR) contributes to ovarian dysfunctions in PCOS patients. Serum amyloid A1 (SAA1) is an acute phase protein produced primarily by the liver response inflammation. In addition its role inflammation, SAA1 may participate IR development peripheral tissues. Yet, expressional regulation of ovary and pathogenesis remain elusive. Methods Follicular fluid granulosa cells were collected from non-PCOS patients with without measure abundance for analysis...

10.21203/rs.3.rs-948461/v1 preprint EN cc-by Research Square (Research Square) 2021-10-05
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