A5005403632- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Colorectal Cancer Treatments and Studies
- Intraperitoneal and Appendiceal Malignancies
- Cancer, Hypoxia, and Metabolism
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
- Helicobacter pylori-related gastroenterology studies
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal disorders and treatments
- Ovarian cancer diagnosis and treatment
- Renal cell carcinoma treatment
- Enhanced Recovery After Surgery
- Neuroblastoma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Ultrasound and Hyperthermia Applications
- Cutaneous Melanoma Detection and Management
- Glioma Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Research Studies
University of L'Aquila
2016-2025
University of Pisa
2023
San Salvatore Hospital
2013-2022
Alma Mater Europaea
2018-2019
Ospedali Riuniti Marche Nord
2017
GTx (United States)
2017
Istituto Oncologico Veneto
2017
Ospedale Madonna Delle Grazie
2017
University of Crete
2017
Hospital Clínic de Barcelona
2017
Abstract Background In Italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. The aim this study was evaluate impact placement on early adverse events undergoing elective surgery. Methods A database retrospectively analysed through a 1:1 propensity score-matching model including 21 covariates. primary endpoint postoperative duration stay, and secondary endpoints were surgical site infections, infectious morbidity rate defined...
Background: Alternative NTRK1/TrkA splicing resulting in TrkAIII expression, originally discovered advanced-stage metastatic neuroblastomas, is also pronounced prostate, medullary thyroid, glioblastoma multiforme, MCPyV-positive Merkel cell, cutaneous malignant melanoma, and pituitary neuroendocrine tumor subsets. In models, exhibits actionable oncogenic activity equivalent to the TrkT3-fused oncogene, cell lines, alternative promoted by hypoxia, nutrient deprivation, endoplasmic reticulum...
BACKGROUND: High adherence to the enhanced recovery after surgery pathway reduces morbidity and mortality rates elective colorectal surgery. OBJECTIVE: To evaluate effect of on failure rescue DESIGN: Retrospective analysis a prospective database. PATIENTS: Adults (≥ 18 years old) who underwent resection with anastomosis for benign malignant disease. SETTINGS: Prospective enrolment in 78 centers Italy from 2019 2021. INTERVENTIONS: All outcomes were measured at 60 days Several patient-,...
Background/Objectives: The indirect impact of the pandemic on diagnosis and treatment new primary melanoma has been carefully evaluated in recent years. aim present study was to investigate if Italy could be detectable also second year pandemic, as suggested by characteristics at diagnosis. Methods: Retrospective analysis 1640 diagnoses cutaneous pre-pandemic period 1292 from 10 centers (from 1 March 2019 28 February 2022). Results: Our findings confirmed an incident melanoma, (Breslow...
Aims and Background The optimal salvage therapy for recurrent ovarian carcinoma has not been clearly established. Response to second-line chemotherapy is low, with a short median survival (8.8-15 months). We investigated the effect of an aggressive approach consisting surgery followed by intraperitoneal drug delivery local hyperthermia. Patients Methods In phase II clinical study, 27 patients advanced/recurrent were treated cytoreductive hyperthermic perfusion. Median patient age was 53...
Background . Some studies suggest that obesity is associated with a poor outcome after Laparoscopic Nissen Fundoplication (LNF), whereas others have not replicated these findings. The effect of body mass index (BMI) on the short- and long-term results LNF investigated. Methods Inclusion criteria were only patients who undergone at least 11-year follow-up data available, preoperative weight height available for calculation BMI (Kg/m 2 ), up to maximum 34.9. Results 201 met inclusion criteria:...
Background: Pancreatic adenocarcinoma has a poor prognosis, resulting in <10% survival rate at 5 years. Modulated electro-hyperthermia (mEHT) been increasingly used for pancreatic cancer palliative care and therapy. Objective: To monitor the efficacy safety of mEHT treatment advanced cancer. Methods: We collected data retrospectively on 106 patients affected by stage III-IV adenocarcinoma. They were divided into 2 groups: who did not receive (no-mEHT) treated with mEHT. performed applying...
Blood transfusions are considered a risk factor for adverse outcomes after colorectal surgery. However, it is still unclear if they the cause (the hen) or consequence egg) of events. A prospective database 4529 resections gathered over 12-month period in 76 Italian surgical units iCral3 study), reporting patient-, disease-, and procedure-related variables, together with 60-day events, was retrospectively analyzed identifying subgroup 304 cases (6.7%) that received intra- and/or postoperative...
Abstract The postoperative course of 159 patients with early gastric cancer operated on between 1974 and 1987 was followed for a median 7.3 years. cumulative 10-year survival rate(s.e.) calculated using follow-up data to the end 1989 90.6(2.7) per cent excluding operative death that from causes other than cancer, or 86.3(3.0) when mortality included. overall 77.3(3.7) cent. Univariate analysis showed significant difference in rates cancers confined mucosa those submucosal invasion (P =...
Gastrectomy for gastric cancer is a significant cause of secondary exocrine pancreatic insufficiency. Pancreatic enzyme replacement therapy may influence nutritional status and quality life after gastrectomy, but the pertinent clinical research to date remains controversial. A randomized controlled trial test this hypothesis was carried out. After 43 patients with were randomly assigned normal diet (Normal-d; n = 21) or supplementation (PES-d; 22) followed up during 12-month period,...
Background: There are interesting studies on glioma therapy with modulated electrohyperthermia (mEHT), which combines heat an electric field. Clinical researchers not only found the mEHT method feasible for palliation but also reported evidence of therapeutic response. Purpose: To study efficacy and safety treatment relapsed malignant astrocytoma versus best supportive care (BSC). Methods: We collected data retrospectively 149 patients affected by astrocytoma. Inclusion criteria were...
Primary objectives of the study were to assess safety transarterial chemoembolization (TACE) using DC Bead LUMI™ for treatment hepatocellular carcinoma and beads distribution after TACE.This was a prospective observational cohort study. The included 44 patients who treated with TACE LUMI. Beads monitored 1 h by CT scan.TACE had no intraprocedural complications. Observed side effects mild intensity pain in 5 (11%), fever 4 (9%) vomiting 2 (5%) patients. Most (89%) reported adverse event....
Since most anastomoses after left-sided colorectal resections are performed with a circular stapler, any technological change in stapling devices may influence the incidence of anastomotic adverse events. The aim present study was to analyze effect three-row stapler on leakage and related morbidity resections.
Several studies report the useful therapeutic results of regional hyperthermia in association with chemotherapy (CHT) and radiotherapy for treatment pancreatic cancer. Modulated electro-hyperthermia (mEHT) is a new technique that induces immunogenic death or apoptosis cancer cells laboratory experiments increases tumor response rate survival patients, offering beneficial effects against this severe type cancer.To assess survival, toxicity mEHT alone combined CHT compared locally advanced...