- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Surgical Treatments
- Pancreatitis Pathology and Treatment
- Hernia repair and management
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic and Acetabular Injuries
- Congenital Diaphragmatic Hernia Studies
- Nutrition and Health in Aging
- Intestinal Malrotation and Obstruction Disorders
- Peripheral Nerve Disorders
- Anesthesia and Pain Management
- Gallbladder and Bile Duct Disorders
- Minimally Invasive Surgical Techniques
- Enhanced Recovery After Surgery
- Bariatric Surgery and Outcomes
- Diverticular Disease and Complications
- Spine and Intervertebral Disc Pathology
- Appendicitis Diagnosis and Management
- Adipose Tissue and Metabolism
- Abdominal Surgery and Complications
- Liver Disease Diagnosis and Treatment
- Urological Disorders and Treatments
- Gastric Cancer Management and Outcomes
- Anorectal Disease Treatments and Outcomes
- Nerve Injury and Rehabilitation
Sapienza University of Rome
2021-2024
Université Paris Cité
2024
Hôpital Louis-Mourier
2024
Assistance Publique – Hôpitaux de Paris
2024
Hôpital Européen Georges-Pompidou
2024
Hôpital Européen
2024
Azienda Ospedaliera San Gerardo
2024
Collaborative Group (United States)
2023
Ospedale Sandro Pertini
2023
ASL Roma
2023
Abstract Background In Italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. The aim this study was evaluate impact placement on early adverse events undergoing elective surgery. Methods A database retrospectively analysed through a 1:1 propensity score-matching model including 21 covariates. primary endpoint postoperative duration stay, and secondary endpoints were surgical site infections, infectious morbidity rate defined...
It is common to observe a gap between the day on which discharge criteria are reached and actual of after colorectal surgery. The aim this study understand reasons for difference its clinical impact overall length stay (LOS). All patients enrolled in prospective iCral3 were analyzed regarding any reason "fit discharge" (FFD) "actual (AD) dates. association LOS whole population was then assessed through multivariate regression model including other confounding variables. analysis included...
Diastasis recti is an abdominal wall defect that occurs frequently in women during pregnancy. Patients with diastasis can experience lower back pain, uro-gynecological symptoms, and discomfort at the level of defect. diagnosed when inter-rectus distance > 2 cm. Several techniques, including both minimally invasive open access surgical treatment, are available. Abdominoplasty plication anterior rectus sheath most commonly used, major limitation requiring a wide skin incision. The new...
We assessed the molecular phenotype of browning white adipose tissue in newly diagnosed cancer patients and controls undergoing surgery for gastrointestinal tumors non-malignant diseases, respectively. collected subcutaneous (SAT) samples using RT-PCR, we analyzed expression markers Western blot protein levels UCP1 PGC1α. The Ucp1 mRNA were lower vs. (p = 0.01), whereas Cidea Tmem26 higher patients. found PGC1α controls, while no differences seen UCP1. was cachectic non-cachectic controls....
During cancer cachexia, several alterations occur in peripheral tissues, and the adipose tissue may be involved during catabolic state. We aimed at investigating histological rearrangement infiltration of inflammatory cells subcutaneous (SAT) patients with undergoing surgery, according to presence/absence cachexia.We considered gastrointestinal controls non-malignant diseases surgery. collected SAT samples performed histomorphological analyses [cross-sectional area (CSA) per cent fibrosis]...
Small non-coding (snc)RNAs, including microRNAs and P-element induced wimpy testis (PIWI)-interacting-RNAs (piRNAs), crucially regulate gene expression in both physiological pathological conditions. In particular, some muscle-specific (myomiRs) have been involved the pathogenesis of cancer-induced muscle wasting. The aims present study were (i) to profile sncRNAs skeletal plasma gastrointestinal cancer patients (ii) investigate association among differentially expressed level muscularity at...
Diastasis recti (DR) is a common condition, especially in women after pregnancy, often associated with concomitant hernia defects and defined as rupture of the midline separation rectus muscle more than 2 cm. Symptoms related to this are low back pain, urinary incontinence pelvic prolapse, well abdominal bulging core instability. We analyzed clinical functional outcomes treatment DR alone or hernias 219 patients who underwent reconstruction using miSAR
A caucasian 62-year-old woman, diagnosed with biphasic pleural mesothelioma (PM) of II stage and BAP1 loss, was treated therapies included in clinical trial Early Access Programmes (EAP). During her history, radiological images presented an unusual representation the disease, a pseudo progression discussed many times by several specialists. The patient's overall survival improved as result multidisciplinary team availability medicines outside practice.
Background: A bilateral diaphragmatic rupture is a rare event that occurs in cases of blunt thoracic-abdominal trauma. Case Presentation: We report the case 56-year-old female patient with pelvic fracture and second-stage diaphragm due to car accident. After chest abdominal contrast-enhanced computed tomography (CT) scan, underwent emergency suturing left hemidiaphragm. On postoperative day (POD) 4, CT scan performed sudden onset dyspnea revealed right hemidiaphragm, which was not detected...
Introduction Liver cancer is globally the fifth most common and fourth cause of cancer-related death.1 Hepatocellular carcinoma (HCC) accounts for about 90% liver cancers associated with a 10%–15% 5-year overall survival rate, mostly because late diagnosis. However, rate reaches 50%–70% when disease diagnosed at an early stage patients can be submitted to curative treatments such as ablation, resection (LR), transplantation.2–4 Hemochromatosis (HH), hereditary autosomal recessive disorder...