A5100393300- Wood and Agarwood Research
- Microbial Metabolism and Applications
- Cultural Heritage Materials Analysis
- Natural product bioactivities and synthesis
- Forensic Fingerprint Detection Methods
- Bioactive Compounds and Antitumor Agents
- Phytochemistry and Biological Activities
- Identification and Quantification in Food
- Biological Stains and Phytochemicals
- Marine Sponges and Natural Products
- Tea Polyphenols and Effects
- Plant biochemistry and biosynthesis
- Synthesis and biological activity
- Oxidative Organic Chemistry Reactions
- Phytochemicals and Antioxidant Activities
- Natural Compound Pharmacology Studies
- Synthesis of Tetrazole Derivatives
- Traditional Chinese Medicine Analysis
- Phytochemistry and Bioactive Compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Forest Ecology and Biodiversity Studies
- Insect and Pesticide Research
- Botanical Research and Applications
- Oral Health Pathology and Treatment
- Insect-Plant Interactions and Control
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
State Administration of Traditional Chinese Medicine of the People's Republic of China
2018-2025
Hainan Medical University
2022-2025
Shandong University of Traditional Chinese Medicine
2022-2025
Nanchang University
2024
The Affiliated Hospital to Changchun University of Chinese Medicine
2024
State Forestry and Grassland Administration
2024
Shandong Agricultural University
2024
People's Hospital of Shiyan
2022
Peking Union Medical College Hospital
2019-2022
Agarwood is the fragrant resin-infused wood derived from wounded trees of Aquilaria species. It a valuable non-timber forest product used in fragrances and as medicine. Reforestation for combination with artificial agarwood-inducing methods serves way to supply agarwood conserve wild stock. However, existing produce poor-quality at low yield. Our study evaluated novel technique producing cultivated trees, called whole-tree (Agar-Wit). Ten different inducers were comparison Agar-Wit three...
In our previous investigation, we found that agarwood essential oil (AEO) has a sedative-hypnotic effect. Sedative-hypnotic drugs usually have an anxiolytic effect, where concomitant anxiety and depression are common comorbidity. Therefore, this study further investigated the antidepressant effects of AEO using series animal behavior tests on restraint stress-induced mice model. The elevated plus maze (EPM) test, light dark exploration (LDE) open field (OF) test demonstrated significant...
Akkermansia muciniphila is considered a next-generation probiotic because of its immense potential to regulate disorders. We isolated 31 strains A. from feces or breast milk healthy people. After genome sequencing, assembly, and analysis, we selected six (AM01 AM06) for further exploration. first analyzed their general characteristics, including morphological description, growth physiological biochemical then confirmed genetic GC content, putative virulence factors, antibiotic resistance...
Abstract Adventitious root (AR) formation from leafy stem cuttings is critical for breeding of many forest and horticultural species. In addition to the plant hormone auxin, wound‐induced signaling caused by cutting excision also essential AR initiation. Here we found that reactive oxygen species (ROS) are rapidly generated at site as a signal propagated throughout hypocotyl after Arabidopsis ( thaliana ) primary root. ROS propagation was not observed in presence an NADPH oxidase inhibitor...
Areca nut (AN), the fruit or seed of catechu Linn, has many uses, including chewing and medicinal purposes. It sparked worries about health due to presence alkaloids. Chewing AN may have a variety negative consequences; however, use no notable adverse effects. To completely understand effectively AN, researchers investigated its chemical makeup biological activity, analyzed variations between different species periods, improved extraction processing procedures. Today, an increasing number...
Background: Depression ranks among the most severe mental health conditions, and poses a burden on global health. Agarwood, an aromatic medicinal plant, has shown potential for improving symptoms. As common folk medicine, agarwood been applied as alternative method disorders such depression through aromatherapy. Previous studies have found that therapeutic effects of aromatherapy are primarily related to its volatile components. This study aimed examine antidepressant properties underlying...
Euphthymifolols A-E (1-5), five undescribed jatrophane diterpenoids feature with a typically 5/12 bicyclic skeleton, were characterised from the aerial parts of Euphorbia thymifolia L. A thorough analysis spectroscopic data and biosynthetic pathway elucidated their planar structures stereoconfiguration. Compound 4 exhibited moderate nitric oxide (NO) inhibitory activity (IC50 63.3 ± 1.94 μM) against LPS-induced BV-2 microglia cells.
Only when Aquilaria spp. or Gyrinops trees are wounded, due to insect attack, microbial invasion, agarwood can be successfully induced. In the present study, a fungus which induce formation efficiently was isolated and suitable method for its application developed. Rigidoporus vinctus from inner layers infectious A. sinensis trees. When fermentation liquid of fungi inoculated back tree, found addition, novel called trunk surface agarwood-inducing technique (Agar-Sit) developed produce with...
Wild Chi-Nan agarwood is regarded as the highest quality from Aquilaria spp. However, comprehensive research on chemical composition of wild limited. An integrated strategy using SHS-GC-MS and UPLC-Q/Tof-MS was applied to explore phytochemical characteristics a kind induced newly identified germplasm A. sinensis. Progenesis QI MS-Dial were used preprocess GC-MS raw data, respectively. Principle component analysis (PCA) orthogonal partial least squares latent structure-discriminant (OPLS-DA)...
Agarwood is generally used to make incense sticks in China and Southeast Asia. It emits smoke with a pleasant odor when burned. There are few reports on the chemical components of generated by burning or heating agarwood. The agarwoods were produced whole-tree agarwood-inducing technique (AWIT), agarwood induced axe wounds (AAW), burning-chisel-drilling (BCDA), wood Aquilaria sinensis trees (AS), respectively. Herein, we GC-MS analyze constituents from AWIT, AAW, BCDA, AS, extracts (EAWIT),...
Background. Agarwood has been used for centuries, especially treatment of gastrointestinal diseases. Earlier studies our laboratory suggested that agarwood alcohol extracts (AAEs) provided gastric mucosal protection. This study aims to investigate the ameliorative effect AAEs on ethanol-induced ulcers and its mechanism. Methods. Mice were given induced by whole-tree agarwood-inducing technique extract (WTAAE, 0.71, 1.42, 2.84 g/kg), wild axe wounds (WAAE, burning-chisel-drilling (FBAAE,...
Depression and anxiety are common diseases that endanger the physical mental health of individuals. Agarwood incense inhalation has been used as a traditional Chinese medicine for relaxation to improve sleep centuries. In previous study by authors it was demonstrated agarwood essential oil (AEO) injection exerted anxiolytic antidepressant effects. Therefore present further investigated effects AEO on mice induced M-chlorophenylpiperazine depressive chronic unpredictable mild stress. The...
Hypatulone A (1), an acylphloroglucinol possessing unprecedented homoadamantane architecture based on a tricyclo-[4.3.1.13,8]-undecane core and unique 5/5/7/6/6 pentacyclic ring system, together with its biogenetic precursor hyperbeanol B (2), was isolated from Hypericum patulum. The structure of 1 elucidated by extensive spectroscopic analysis electronic circular dichroism calculation. Its plausible biosynthetic pathway via Wagner–Meerwein rearrangement proposed. exhibited nitric oxide...