A5066474893- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Genetic factors in colorectal cancer
- Lung Cancer Research Studies
- Bladder and Urothelial Cancer Treatments
- Gastrointestinal Tumor Research and Treatment
- Diverticular Disease and Complications
- Inflammatory mediators and NSAID effects
- Cancer, Lipids, and Metabolism
- Metastasis and carcinoma case studies
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Estrogen and related hormone effects
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Diagnosis and Treatment
- Stoma care and complications
- Neuroblastoma Research and Treatments
- Lymphoma Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Bleeding Diagnosis and Treatment
Juntendo University
2015-2024
Tokyo Metropolitan Geriatric Hospital
2022
Juntendo University Hospital
2021
National Cancer Center Hospital East
2014-2018
Creative Commons
2018
Juntendo University Nerima Hospital
2015
Juntendo University Shizuoka Hospital
2014
Kobe University
2009
University Medical Center New Orleans
1998
Louisiana State University
1998
Generally, cancer tissue is palpated as a hard mass. However, the elastic nature of not well understood. The aim present study was to evaluate clinical utility measuring modulus (EM) in colorectal tissue. Using tactile sensor, we measured EM 106 surgically resected tissues. Data on were compared with clinicopathological findings, including stromal features represented by Azan staining and α-SMA positive area ratio tumor area. Finally, cDNA microarray profile tumors high findings low EM. A...
A new histological classification of neuroendocrine tumors (NETs) was established in WHO 2010. ENET and NCCN proposed treatment algorithms for colorectal NET. Retrospective study NET the large intestine (colorectal appendiceal NET) performed among institutions allied with Japanese Society Cancer Colon Rectum, 760 from 2001 to 2011 were re-assessed using 2010 criteria elucidate clinicopathological features intestine. Next, relationship lymph node metastasis analyzed predict locally resected...
Pathological studies on the different histological effects between neoadjuvant chemotherapy (NAC) and preoperative chemoradiation therapy (preoperative CRT) have not been performed. The purpose of this study is to elucidate differences in tissue received from NAC CRT for rectal cancer evaluate whether a pathological assessment method used after can be applied NAC. One hundred thirty-eight patients were enrolled study; 88 underwent their operations or NAC, 50 surgery only. Residual tumor area...
The aim of this study was to elucidate differences in the histological features rectal cancer between patients treated with preoperative chemoradiotherapy and those chemotherapy. Area residual tumor (ART) also evaluated for its utility as a potential prognostic marker them. Sixty-eight who underwent sphincter-saving surgery were enrolled study. Of these, 39 received (CRT group) 29 (neoadjuvant) chemotherapy (NAC group). determined by using morphometric software. Tumors two groups compared...
Transgelin is an actin-binding protein expressed in smooth muscle cells, cancer cells and fibroblasts. While has previously been reported to be a tumor suppressor, recent studies have shown that involved carcinogenesis, with its mRNA expression associated poor prognosis colorectal cancer. To date, however, very few clinicopathological conducted on tissue. The aim of this study was therefore elucidate the role stromal cells. Ninety-six patients undergoing curative surgery for between February...
BACKGROUND There are 3 methods of treating T1 colorectal cancer (T1 CRC), which include endoscopic resection, resection followed by additional and surgical resection. In this retrospective study, changes in the management CRC after introduction submucosal dissection (ESD) were investigated comparison with 10-year period before ESD. MATERIAL AND METHODS During a 20-year from 1996 to 2015, 835 patients treated, including 331 ESD (Group A) 504 B). Clinicopathological findings treatment compared...
Background: Few previous studies have investigated the relationship between serum oxidative stress and status of patients with colorectal cancer. Our aim in current study was to investigate significance as a prognostic marker these patients.
Primary malignant lymphoma of the brain (PMLB) is uncommon. Between 1975 and 1982, authors observed 11 patients with histologically confirmed PMLB. Mean survival after radiation therapy was 7 months 5 surviving for more than 2 years. Multifocal lesions were seen in 9 spontaneous regression at computed tomography patients. Radiation doses excess 30 Gy controlled primary tumor, but intracranial recurrences occurred even whole irradiation to 40 Gy. Only one patient had a relapse outside central...
Purpose A consensus has been reached regarding diverting stoma (DS) construction in rectal cancer surgery to avoid reoperation related anastomotic leakage. However, the incidence of stoma-related complications (SRCs) remains high. In this study, we examined perioperative outcomes DS patients who underwent sphincter-preserving for cancer. Methods We included 400 participants radical between 2005 and 2017. These were divided into (+) (–) groups, outcomes, including postoperative complications,...
Abstract Rectal neuroendocrine tumors (NETs) are often found as small lesions, which can be treated by endoscopic resection. However, high risk cases with lymph node (LN) metastasis indication of radical surgery. Furthermore, rectal NETs associated late recurrences and/or multiple cancer development. Therefore, proper surgical and patients’ management required. We investigated the clinicopathological features 79 NET in order to elucidate factors for synchronous LN metastasis, recurrence,...
Abstract We report a case in which analysis of copy number variation revealed local recurrence submucosal invasive colorectal cancer after curative endoscopic dissection (ESD). An 86‐year‐old man with history abdominoperineal resection the rectum for rectal underwent ESD early‐stage sigmoid 5 cm away from stoma opening. At same time, ileocecal was performed advanced cecal cancer. Twelve months ESD, occurred area lesion. It unclear if implantation cancer, or new Copy three lesions that lesion...
Superior mesenteric artery syndrome (SMAS) is a relatively rare disease that involves bowel obstruction symptoms, such as vomiting and gastric distension, owing to the compression of third portion duodenum from front by superior (SMA) rear abdominal aorta spine. SMAS diagnosed on basis an upper gastrointestinal examination series indicating or computed tomography scan narrowing branch angle between SMA (i.e., aorta-SMA angle). Here, we report case 78-year-old woman with after laparoscopic...
We investigated whether promoter methylation of the checkpoint-with-forkhead-and-ring-finger-domains (CHFR) gene is a predictor efficacy irinotecan-based systemic chemotherapy for advanced colorectal cancer (CRC) patients.CHFR-promoter was measured by quantitative methylation-specific PCR (qMSP). The histoculture drug response assay (HDRA) used in vitro to analyze correlation between CHFR-promoter and irinotecan-active-metabolite SN38 colorectal-cancer tissues from 44 CRC patients. CHFR...
The goal of this retrospective study was to identify prognostic factors associated with mortality after surgery for colorectal perforation among patients connective tissue disease (CTD) and review postoperative outcomes based on these factors.The subjects were 105 (CTD group: n=26, 24.8%; non-CTD n=79, 75.2%) who underwent at our department. Cases iatrogenic due colonoscopic examination excluded from the study. We retrospectively investigated perioperative clinicopathological in undergoing...
Objective: Anastomotic leakage (AL) is one of the most serious postoperative complications in colorectal surgery. AL reportedly occurs 5-10% cases following Poor colonic perfusion proceeded to be during mesenteric resection. The purpose this study was evaluate clinical utility assessing with indocyanine green (ICG) fluorescence imaging.
Abstract Background Urothelial carcinoma arises from transitional cells in the urothelial tract. In advanced cases, it can metastasize locally to surrounding organs or distally such as lungs, bones, liver. Here we describe a case of rectal metastasis treated with multiple sessions transurethral resection bladder tumor (TURBT). Case presentation A 72-year-old woman presented our department abdominal bloating andobstructed defecation. She had undergone two TURBT for early another hospital at...
症例は62歳の男性．2002年11月に検診で発見された胃癌に対し幽門側胃切除術を施行した．病理所見はtype0-IIc+IIa，37×27mm，por1，pT1b，INFa，ly3，v1，N2，pStage IIAであった．術後補助療法は施行せず，経過観察中であった．2003年2月より，ふらつき・頭痛が出現し精査施行したところ，右小脳に3.0cm大の転移性脳腫瘍を指摘．脳内の他部位に転移巣を認めず，肝肺局所に再発所見は認めなかった．右小脳転移性脳腫瘍に対し開頭腫瘍摘出術を施行．術後経過は良好であり，現在術後10年以上無再発生存している．胃癌からの脳転移は，全身に転移が認められた後の末期的な状態として発見される場合が多く，今回の症例のように孤立性に転移をきたすことは稀である．今回，われわれは胃癌術後に発症した孤立性小脳転移に対し加療により良好な予後を得られた1例を経験したので，文献的考察を加えて報告する．
In this study, an electronic endoscope was applied for observation of gastric submucosal vessels, with infrared illumination, in anesthetized dogs. An in-vivo spectrophotometry showed that light at 620-820 nm penetrates the abdominal and wall. During endoscopy performed dogs, radiation penetrated wall from outside, detected by endoscope's charge-coupled device. A television monitor displayed a network vasculature, which identified as veins injecting saline or indocyanine green into vein....
Objective: It is difficult to conduct a randomised control trial in single institution because of the small number cases. The current study was conducted investigate if there any difference long-term outcome between laparoscopic surgery (LAC) and open (OC) using propensity-score matching analysis based on prognostic factors.
Laparoscopic colectomy was first used for the treatment of colorectal cancer early in 1990s, before spreading rapidly throughout world. In comparison with open surgery, laparoscopic has advantages smaller incision, less pain, and faster recovery during postoperative period. Randomized controlled trials (RCTs) have compared it demonstrating similarities terms complications long-term prognosis.
To determine mortality and predictive factors for lower intestinal perforation (LIP) among patients with autoimmune rheumatic diseases.This retrospective, single-center, observational study analyzed rates in 31 disease LIP who were admitted to our hospital from January 2002 June 2017. The primary outcome was the rate during hospitalization.The median age at time of 61 years, survival discharge 64.5%. Eleven died sepsis hospitalization. Cox univariable analysis hospitalization showed that...
The extent of tumor spread influences on the clinical outcome, and which determine T stage colorectal cancer. However, pathologic discrimination between pT3 pT4a in eighth edition American Joint Committee Cancer (AJCC)-TNM is subjective, more objective method for deeply invasive advanced colon cancer mandatory standardized patient management. Peritoneal elastic laminal invasion (ELI) detected using staining may increase In this study, we constructed ELI study group to investigate...