A5064355894- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Cardiac tumors and thrombi
- Vascular Tumors and Angiosarcomas
- Musculoskeletal synovial abnormalities and treatments
- Management of metastatic bone disease
- Bone health and treatments
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Nerve Injury and Rehabilitation
- Epigenetics and DNA Methylation
- Reconstructive Surgery and Microvascular Techniques
- Shoulder Injury and Treatment
- Molecular Biology Techniques and Applications
- Testicular diseases and treatments
- Gastric Cancer Management and Outcomes
- Cancer-related molecular mechanisms research
- Artificial Intelligence in Healthcare and Education
- Bone fractures and treatments
- Lymphoma Diagnosis and Treatment
- Bone and Joint Diseases
- Surgical site infection prevention
- Ocular Infections and Treatments
- Congenital Anomalies and Fetal Surgery
Samsung Medical Center
2014-2024
Sungkyunkwan University
2014-2024
Samsung (South Korea)
2019-2022
Chungbuk National University
2019
Samsung (United States)
2018
Ghent University Hospital
2018
Samsung Medison (South Korea)
2018
Clinical Orthopaedics and Related Research
2018
Biosolution (South Korea)
2016
University of California, San Diego
2014
Objectives:The aim of this study was to develop a new prognostic classification for epithelial ovarian cancer (EOC) patients using gradient boosting (GB) and compare the accuracy model with conventional statistical method.Methods: Information EOC from Samsung Medical Center (training cohort, n=1,128) analyzed optimize GB.The performance final externally validated patient information Asan (validation n=229).The area under curve (AUC) by GB compared that Cox proportional hazard regression...
The treatment goal in lateral condylar fracture is union without residual deformity. However, growth disturbance may occur despite initial anatomic reduction and secure fixation. purpose of this study was to evaluate the clinical functional results, including complications, treatments children, identify differences between methods.One hundred seventy-five patients followed for more than a year with available final follow-up radiographs were included. Carrying angle range motion limitations...
We compared the accuracy of growth remaining method assessing leg-length discrepancy (LLD) with straight-line graph method, multiplier and their variants. retrospectively reviewed records 44 patients treated by percutaneous epiphysiodesis for LLD. All were followed up until maturity. used modified Green–Anderson growth-remaining (Method 1) to plan timing epiphysiodesis. Then we presumed that other four methods described below pre-operatively calculating then assumed these pre-operatively....
Abstract The main treatment for chondrosarcoma is surgical resection with a wide margin. However, there are certain chondrosarcomas, such as those found in the pelvis and spine, which cannot be resected adequately surgery alone. Unfortunately, most chondrosarcomas resistant to radiation chemotherapy. Radiation chemotherapy thought kill cells by inducing apoptosis, or programmed cell death. In this article, we hypothesize that antiapoptotic gene silencing enhances radiosensitivity...
Prognosis and optimal treatment strategies of liposarcoma have not been fully defined. The purpose this study is to define the distinctive clinical features liposarcomas by assessing prognostic factors. Between January 1995 May 2008, 94 patients who underwent surgical resection with curative intent were reviewed. Fifty (53.2%) presented well differentiated, 22 (23.4%) myxoid, 15 (16.0%) dedifferentiated, 5 (5.3%) round cell, 2 (2.1%) pleomorphic histology. With median 14 cm sized tumor...
Prader-Willi syndrome (PWS) is a rare genetic disorder with an associated anomaly in chromosome 15, and has been reported to increase prevalence of scoliosis, but little information available regarding its association other musculoskeletal manifestations. The aim this study was evaluate manifestations 36 patients PWS determine the effects risk factors, such as, sex, age, genotype, body mass index (BMI) on PWS.The investigators subjected complete physical examination radiographic assessment...
Abstract Purpose Given the increasing significance and potential impact of artificial intelligence (AI) technology on health care delivery, there is an demand to integrate AI into medical school curricula. This study aimed define competencies identify essential for graduates in South Korea. Method An initial Delphi survey conducted 2022 involving 4 groups experts (n = 28) yielded 42 competency items. Subsequently, online questionnaire was carried out with 1,955 participants (1,174 students...
The authors conducted the present study to identify clinical and radiological prognostic factors in infants neonates with septic arthritis of hip. retrospectively reviewed records 31 patients All were younger than 18 months old. Follow-up periods ranged from 5 17 years. following potential variables for predicting prognosis included assessment: gender, age, underlying diseases, duration symptoms, changes hip joint X-ray, concomitant osteomyelitis, elevation erythrocyte sedimentation rate...
The physical and chemical properties of a matrix play an important role in determining various cellular behaviors, including lineage specificity. We demonstrate that the differentiation commitment human embryonic stem cells (hESCs), both vitro vivo, can be solely achieved through synthetic biomaterials. hESCs were cultured using mineralized matrices mimicking calcium phosphate (CaP)-rich bone environment differentiated into osteoblasts absence any osteogenic inducing supplements. When...
Background: Implant loosening is associated with inflammatory bone loss induced by ultra-high molecular weight polyethylene wear debris. We hypothesized that a hydroxyapatite-bisphosphonate composite improves periprosthetic quality and osseous integration of an intramedullary implant even in the presence particles experimental rat femur model. Methods: A preliminary vitro study determined optimal concentration zoledronate (50 μM) would maximally decrease osteoclasts without harming...
No feasible method currently exists to evaluate systemic metastasis in patients with myxoid liposarcoma. The purpose of this study was determine the feasibility performing whole-body magnetic resonance imaging (MRI) detect metastatic From June 2008 May 2010, all who were newly diagnosed liposarcomas at our institution underwent MRI along other conventional methods. We divided whole body into 38 sections (7 soft tissue and 31 bone sections). In total, there 570 regions (105 465 bony regions)...
Gastric cancer (GC) is the third-leading cause of cancer-related deaths. Several pivotal clinical trials adjuvant treatments were performed during previous decade; however, optimal regimen for treatment GC remains controversial.We developed a novel deep learning-based survival model (survival recurrent network [SRN]) in patients with by including all available and pathologic data regimens. This uses time-sequential only training step, upon being trained, it receives initial from first visit...
We retrospectively reviewed the outcomes of desmoid tumor (DT) patients treated by surgical excision.Among 155 consecutive patients, 119 satisfied our inclusion criteria. The mean follow-up duration was 82 months. Age, gender, location, size, depth, resection margin, adjuvant radiotherapy, and excision history were analyzed for outcomes.The recurrence-free survival (RFS) rates 75% at 5 years 72% 10 years. Twenty-seven (93.1%) out 29 recurrences detected within In multivariate analysis,...
The oncologic risk of ionizing radiation is widely known. Sarcomas developing after radiotherapy have been reported, and they are a growing problem because rapid advancements in cancer management screening increased the number long-term survivors. Although many patients undergone treatment Asian countries, scarce reports on post-radiation sarcomas (PRSs) published. We investigated feature prognostic factors PRSs an population. Eastern Musculoskeletal Oncology Group participated this project....
Extraosseous osteosarcoma (EOO) is a rare soft tissue form of without involvement the skeletal system. Due to rarity disease, its clinical features and optimal treatment are yet be defined.Between 1 January 1999 30 June 2008 ten patients were pathologically confirmed with extra-skeletal osteosarcoma. A retrospective analysis was performed.The anatomical distribution osteosarcomas as follows: lower extremities (n = 3), upper 2), breast lung 1), cheek 1) retroperitoneum 1). Nine initially...
Screening for genes or markers relevant to bladder cancer (BC) tumorigenesis and progression is of vital clinical significance. The present study used reverse-transcription quantitative PCR reaction assays examine the expression mRNA encoding Rho GTPase-activating protein 9 (ARHGAP9) in BC tissue samples determine whether ARHGAP9 an independent prognostic biomarker non-muscle invasive (NMIBC) muscle (MIBC). results revealed that downregulation patients with NMIBC MIBC was significantly...
The purpose of this study was to evaluate the effectiveness supracondylar lateral closing-wedge osteotomy humerus in children and postoperative remodeling condylar prominence. Lateral for cubitus varus deformity performed 52 children. In all cases, medial translation decreasing prominence or transposition ulnar nerve not performed. Mean patient age 8.8 years. follow-up 42 months. Clinical radiological results were analyzed at last follow-up. range motion elbow flexion extension improved...