A5045351334- Hepatitis C virus research
- Hepatitis B Virus Studies
- Monoclonal and Polyclonal Antibodies Research
- Extracellular vesicles in disease
- Advanced X-ray and CT Imaging
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- HIV Research and Treatment
- MXene and MAX Phase Materials
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Nanchang University
2017-2024
Institut Pasteur of Shanghai
2016-2020
Chinese Academy of Sciences
2020
Shanghai Institutes for Biological Sciences
2016-2019
Shanghai University
2019
Second Affiliated Hospital of Nanchang University
2017
Pleural effusion (PE) is a common clinical complication of many pulmonary and systemic diseases, including lung cancer tuberculosis. Nevertheless, there no effective biomarker to identify the cause PE. We attempted investigate differential expressed exosomal miRNAs in PEs adenocarcinoma (APE), tuberculous (TPE), other benign lesions (NPE) by using deep sequencing quantitative polymerase chain reaction (qRT-PCR). As result, 171 differentiated were observed 3 groups PEs, 11 significantly...
Hepatitis A virus (HAV), a classic nonenveloped virus, has recently been found to be released mainly in the form of quasi-enveloped HAV (eHAV) by hijacking host endosomal sorting complexes required for transport (ESCRT) complexes. Unlike virion, eHAV contains viral protein pX on surface capsid as an extension VP1. How capsids acquire envelope and whether is involved this process were previously unknown. Here, we analyse role foreign secretion exosome-like extracellular vesicles (EVs)...
Hepatitis C virus (HCV) infects 2 to 3% of the world population and is a leading cause liver diseases such as fibrosis, cirrhosis, hepatocellular carcinoma. Many aspects HCV study, ranging from molecular virology antiviral drug development resistance profiling, were supported by straightforward assays replication infection. Among these assays, HCV-dependent fluorescence relocalization (HDFR) system allowed live-cell visualization infection without modifying viral genome, but this strategy...
Hepatitis C virus (HCV) spread involves two distinct entry pathways: cell-free transmission and cell-to-cell transmission. Cell-to-cell is not only an efficient way for viruses to but also effective method escaping neutralizing antibodies. We adapted the viral infection-activated split-intein-mediated reporter system (VISI) developed a straightforward model Live-cell monitoring of HCV ex-vivo: co-culture infected donor cells (red signal) with uninfected recipient (green elimination by adding...