A5085408448- Fatty Acid Research and Health
- Nutritional Studies and Diet
- Cancer, Lipids, and Metabolism
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Electroconvulsive Therapy Studies
- Advanced biosensing and bioanalysis techniques
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Fibroblast Growth Factor Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Neuroscience and Neuropharmacology Research
- Atomic and Subatomic Physics Research
- Diet, Metabolism, and Disease
- Advanced MRI Techniques and Applications
- RNA Interference and Gene Delivery
- Metabolomics and Mass Spectrometry Studies
- Memory and Neural Mechanisms
- Ferroptosis and cancer prognosis
- DNA and Nucleic Acid Chemistry
- Immune cells in cancer
- Lipid metabolism and biosynthesis
- Renal cell carcinoma treatment
Tongren Hospital
2025
Shanghai Jiao Tong University
2025
Sun Yat-sen University
2022-2023
Henan Provincial People's Hospital
2023
Qilu Hospital of Shandong University
2023
Henan University of Traditional Chinese Medicine
2023
The Affiliated Yongchuan Hospital of Chongqing Medical University
2015-2019
Chongqing Medical University
2015-2019
Abstract Liver metastasis is the main cause of death in patients with colorectal cancer (CRC); thus, necessitating effective biomarkers and therapeutic targets for liver (CRLM). Fibroblast growth factor 19 (FGF19) a protumorigenic gene numerous human malignancies. In this study, it shown that FGF19 plays an indispensable role CRLM. expression secretion are markedly correlated lower overall survival rates CRC. An vivo model shows overexpression confers stronger liver‐metastatic potential CRC...
The prognosis of hepatocellular carcinoma (HCC) is still poor largely due to the high incidence recurrence. We aimed develop and validate predictive models early postoperative recurrence for HCC using clinical gadoxetic acid-enhanced magnetic resonance (MR) imaging-based findings.In this retrospective case-control study, 209 patients, who underwent MR imaging before curative-intent resection, were enrolled. Boruta algorithm backward stepwise selection with Akaike information criterion (AIC)...
The association between circulating saturated fatty acids (SFAs) including very long-chain SFAs (VLCSFAs) and colorectal cancer (CRC) risk has not been clearly established. To investigate the serum CRC in Chinese population, 680 cases sex age-matched (5-year interval) controls were recruited our study. Serum levels of detected by gas chromatography. Unconditional logistic regression models used to estimate odds ratios (ORs) 95% confidence intervals (CIs) for risk. Results showed that total...
Circulating n-3 PUFA, which integrate endogenous and exogenous can be better used to investigate the relationship between PUFA disease. However, studies examining associations circulating colorectal cancer (CRC) risk were limited, results remained inconclusive. This case–control study aimed examine association serum CRC in Chinese population. A total of 680 cases sex- age-matched (5-year interval) controls included. Fatty acids assayed by GC. OR 95 % CI calculated using multivariable...
The hepatobiliary-specific phase can help in early detection of changes lesion tissue density, internal structure, and microcirculatory perfusion at the microscopic level has important clinical value hepatocellular carcinoma (HCC). Therefore, this study aimed to construct a preoperative nomogram for predicting positive expression glypican-3 (GPC3) based on gadoxetic acid-enhanced (Gd-EOB-DTPA) MRI hepatobiliary (HBP) radiomics, imaging feature.We retrospectively included 137 patients with...
Abstract The relationship between erythrocyte membrane n -3 PUFA and breast cancer risk is controversial. We aimed to examine the associations of with odds among Chinese women by using a relatively large sample size. A case–control study was conducted including 853 newly diagnosed, histologically confirmed cases 892 frequency-matched controls (5-year interval). Erythrocyte were measured GC. Logistic regression restricted cubic spline used quantify association cancer. α -linolenic acid (ALA),...
Dietary n - 3 polyunsaturated fatty acids (PUFAs) were found to be inversely associated with breast cancer risk; however, the underlying pathways between them remain uncertain. We aimed explore serial mediatory roles of erythrocyte PUFAs in association dietary and risk. Using a case-control study, 850 cases 861 controls completed structured questionnaires information. Erythrocyte measured by gas chromatography. Odds ratios (ORs) 95% confidence intervals (CIs) obtained using multiple...
Abstract Objective To screen cuproptosis-relatedlncRNAs and establish a prognostic model of cuproptosis-related lncRNAs in hepatocellular carcinoma (HCC). Methods Perl R languages were used to collate the HCC transcriptome clinical data downloaded from TCGA database. Cuproptosis-related obtained through co-expression analysis, total samples randomly divided into Train group Test group. Univariate Cox regression LASSO multivariate analysis analyze lncRNAs. The accuracy was verified by...