A5022201148- Functional Brain Connectivity Studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Neurological disorders and treatments
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Endometriosis Research and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Lower Extremity Biomechanics and Pathologies
- Neuroscience and Neuropharmacology Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Gynecological conditions and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Mental Health Research Topics
- Pelvic and Acetabular Injuries
- Bone Tumor Diagnosis and Treatments
- Foot and Ankle Surgery
- Lung Cancer Diagnosis and Treatment
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
Chongqing Medical University
2015-2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2015-2025
University of Shanghai for Science and Technology
2024
Soochow University
2024
Shanghai Sixth People's Hospital
2024
Capital Medical University
2024
Shanghai Jiao Tong University
2024
Shanghai First People's Hospital
2024
BackgroundArtificial intelligence (AI) models in real-world implementation are scarce. Our study aimed to develop a CT angiography (CTA)-based AI model for intracranial aneurysm detection, assess how it helps clinicians improve diagnostic performance, and validate its application clinical implementation.MethodsWe developed deep-learning using 16 546 head neck CTA examination images from 14 517 patients at eight Chinese hospitals. Using an adapted, stepwise evaluation, 120 certified 15...
Adolescent major depressive disorder (MDD) is associated with serious adverse implications for brain development and higher rates of self-injury suicide, raising concerns about its neurobiological mechanisms in clinical neuroscience. However, most previous studies regarding the alterations adolescent MDD focused on single-modal images or analyzed different modalities separately, ignoring potential role aberrant interactions between structure function psychopathology.
Background: It has remained a concern whether any long-term pulmonary sequelae exist for COVID-19 survivors. Methods: Forty-one patients (22 men and 19 women, 50 ± 14 years) confirmed with performed follow-up chest CT cardiopulmonary exercise testing at 7 months after discharge. Patients were divided into fibrosis group non-fibrosis according to the evidence of on CT. The clinical data findings recorded analyzed. Results: predominant patterns abnormalities observed discharge parenchymal band...
Essential tremor (ET) is one of the most common movement disorders in human adults. It can be characterized as a progressive neurological disorder which recognizable feature arms or hands that apparent during voluntary movements such eating and writing. The pathology ET remains unclear. Resting-state fMRI (RS-fMRI), non-invasive imaging technique, was employed to investigate abnormalities functional connectivity brain. Regional homogeneity (ReHo) used metric RS-fMRI assess local abnormality...
The clinical benefits of targeting the ventral intermediate nucleus (VIM) for treatment tremors in essential tremor (ET) patients suggest that VIM is a key hub network generation and propagation can be considered as seed region to study network.However, little known about central ET patients.Twentysix 26 matched healthy controls (HCs) were included this study.After considering structural head-motion factors establishing accuracy our region, seedbased functional connectivity (FC) analysis...
This study aimed to develop a nomogram combining CT-based handcrafted radiomics and deep learning (DL) features preoperatively predict muscle invasion in bladder cancer (BCa) with multi-center validation.
Abstract Major depressive disorder is associated with abnormal anatomical and functional connectivity, yet alterations in whole cortical thickness topology remain unknown. Here, we examined medication-free adult depression patients ( n = 76) matched healthy controls 116). Inter-regional correlation was performed to construct brain networks. By applying graph theory analysis, global (i.e., small-worldness) regional (centrality) compared between major controls. We found that patients,...
Patients with subcortical ischemic vascular disease (SIVD) exhibit a high risk of cognitive impairment that might be caused by neurologic deficits and injuries. However, the mechanism remains unknown. In current study, 24 normal controls (NC) 54 SIVD patients, including 26 patients no (SIVD-NCI) 28 mild (SIVD-MCI) underwent resting-state functional MRI (rs-fMRI) neuropsychological assessments. We combined regional homogeneity (ReHo) cerebral blood flow (CBF) using global ReHo-CBF...
To evaluate the mid-term symptom improvement of patients with different types adenomyosis based on magnetic resonance imaging (MRI) classification after ultrasound-guided high intensity focused ultrasound (USgHIFU) treatment.A total 321 who underwent HIFU and completed 18-month follow-up were retrospectively reviewed. Based relationship between adenomyotic lesion uterine structural components T2-weighted (T2WI), lesions classified as internal, external, full thickness intramural adenomyosis....
Abstract Objective To develop a computed tomography (CT) radiomics-based interpretable machine learning (ML) model to preoperatively predict human epidermal growth factor receptor 2 (HER2) status in bladder cancer (BCa) with multicenter validation. Methods In this retrospective study, 207 patients pathologically confirmed BCa were enrolled and divided into the training set ( n = 154) test 53). Least absolute shrinkage selection operator (LASSO) regression was used identify most...
The quadriceps during activities mainly affect patellar movement in the sagittal plane. This study was to analyze pattern of tilt patellofemoral pain (PFP) patients by four-dimensional computed tomography (4DCT). Thirty-four knees PFP and 34 control were scanned with 4DCT. Patella-patellar tendon angle (P-PTA), patella-lateral tibial plateau (P-LTPA), patella-screen horizontal line (P-SHLA), articular facet (PA-LTPA), (PA-SHLA), upper margin patella-quadriceps (PU-QTA) used evaluate tilt....
Background: Accurate staging of cervical cancer via conventional magnetic resonance imaging (MRI) remains challenging, suggesting a greater need for coil placement closer to the region interest. This study aimed determine value 3.0-T MRI with an endovaginal combined pelvic array (combined coil) in preoperative and its correlation histopathology. Methods: Patients who received MR scans from January 2023 March 2024 at The First Affiliated Hospital Chongqing Medical University were included...
Background Psychotherapy has demonstrated comparable efficacy to antidepressant medication in the treatment of major depressive disorder. Metabolic alterations MDD state and response have been detected by functional imaging methods, but underlying white matter microstructural changes remain unknown. The goal this study is apply diffusion tensor techniques investigate psychotherapy-specific responses matter. Methods Twenty-one forty-five outpatients diagnosed with depression underwent before...
Abstract Background Accurate preoperative assessment of the efficacy high-intensity focused ultrasound (HIFU) ablation for uterine fibroids is essential good treatment results. The aim this study was to develop robust radiomics models predicting prognosis HIFU-treated and explain internal predictive process model using Shapley additive explanations (SHAP). Methods This retrospective included 300 patients with who received HIFU were classified as having a favorable or unfavorable based on...
Major depressive disorder (MDD) and bipolar (BD) share clinical features, which complicates their differentiation in settings. This study proposes an innovative approach that integrates structural connectome analysis with machine learning models to discern individuals MDD from BD. High-resolution MRI images were obtained diagnosed or BD HCs. Structural connectomes constructed represent the complex interplay of brain regions using advanced graph theory techniques. Machine employed unique...
Background: Considering that patellofemoral pain (PFP) is related to dynamic factors, extension on 4-dimensional computed tomography (4-DCT) may better reflect the influence of muscles and surrounding soft tissue than static extension. Purpose: To compare characteristics alignment between knee position in patients with PFP controls via 4-DCT. Study Design: Cross-sectional study; Level evidence, 3. Methods: Included were 39 knees (25 patients) 37 control (24 participants). For each knee, an...