A5018745309- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Prostate Cancer Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Cancer and Skin Lesions
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Cell Adhesion Molecules Research
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Cancer Diagnosis and Treatment
- Estrogen and related hormone effects
- Urinary and Genital Oncology Studies
- Monoclonal and Polyclonal Antibodies Research
- Bone health and treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Ovarian cancer diagnosis and treatment
- Oral and Maxillofacial Pathology
- Cancer Cells and Metastasis
- Sarcoma Diagnosis and Treatment
- Genital Health and Disease
- Urinary Bladder and Prostate Research
University of Samarra
2024
Northeast Ohio Medical University
2024
Al-Nisour University College
2023
Al Noor University College
2023
HCA Healthcare
2022
Vanderbilt University
2013-2021
Vanderbilt University Medical Center
2011-2020
University of Duhok
2019
Iraqi University
2018
HCA Midwest Division
2018
The distant organs to which breast cancer preferentially metastasizes are of significant clinical importance.We explored the relationship between clinicopathologic factors and common sites metastasis in 531 consecutive patients with advanced cancer.Breast subtype as a variable was significantly associated all five relapse by multivariate analysis. luminal tumors were remarkable for their bone-seeking phenotype less frequently observed lung, brain, pleural metastases likely be multiorgan...
Angiogenesis, or neovascularization, is known to play an important role in the neoplastic progression leading metastasis. CD31 Factor VIII-related antigen (F VIII RAg) immunohistochemistry widely used experimental studies for quantifying tumor neovascularization immunocompromised animal models implanted with transformed human cell lines. Quantification, however, can be affected by variations methodology measure vascularization including antibody selection, retrieval (AR) pretreatment, and...
Background:PIM1 kinase is coexpressed with c-MYC in human prostate cancers (PCs) and dramatically enhances c-MYC-induced tumorigenicity. Here we examine the effects of a novel oral PIM inhibitor, AZD1208, on tumorigenesis recurrence.
Distinguishing bladder muscularis propria from mucosae can be problematic especially in transurethral resection specimens performed for carcinoma. Moreover, carcinoma associated with a proliferative/desmoplastic myofibroblastic response that resemble smooth muscle and potentially lead to overdiagnosis of invasion. The aim this study was investigate the potential role immunohistochemistry staging by evaluating expression different markers myofibroblasts nonvascular cells 15 cases invasive...
BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has been anticipated to improve communication between pathologists and clinicians thereby patient outcomes. In the current study, impact of TBSRTC on various quality outcome measures was assessed. METHODS: study included all patients who underwent fine-needle aspiration (FNA) thyroid April 2006 2009. Before implementation, authors used generic diagnostic categories; after used. Quality reporting, categories, rate...
BACKGROUND Benign prostatic hyperplasia (BPH) is a common, chronic progressive disease. Inflammation associated with enlargement and resistance to 5α‐reductase inhibitor (5ARI) therapy. Activation of the nuclear factor‐kappa B (NF‐κB) pathway linked both inflammation ligand‐independent prostate cancer progression. METHODS NF‐κB activation androgen receptor variant (AR‐V) expression were quantified in transition zone tissue samples from patients wide range AUASS incidental BPH treated for low...
The diagnosis of prostatic carcinoma and especially minimal can sometimes be challenging on needle core biopsy occasionally immunohistochemistry is an aid in the diagnosis. Immunostains, such as those directed against basal cell marker p63 and, more recently, employing antibodies reactive with α-methylacyl-CoA racemase (AMACR), useful this situation. aim investigation was to assess diagnostic utility a p63/AMACR antibody cocktail compare staining pattern it produces that using individual...
TTF-1 and napsin A are useful biomarkers for differentiating primary lung adenocarcinoma from metastatic tumors. Studies have shown, however, that also can be expressed in extrapulmonary carcinomas, a small fraction of adenocarcinomas do not co-express these two markers. We attempted to determine whether tissue-specific transcriptional factor, PAX8, help sites carcinomas. Immunohistochemical stains were performed on 103 cases carcinomas variety origins 120 adenocarcinomas. Our data...
Syndecan-1 expression is decreased in diverse tumor types but remains controversial breast carcinomas. The goal of the study was to examine syndecan-1 carcinoma and its prognostic significance.The epithelial examined tissue microarrays constructed from 62 consecutive cases diagnosed between 1997 2004 with distant organ metastasis 10 control (breast no after at least 8 years follow-up). significance estimated by utilizing a Cox proportional hazards regression model.Among tumors metastasis,...
Hepatoid carcinomas are tumors that display, at least focally, cytologic and/or architectural features of hepatocellular carcinoma. They have been described in several organs, most notably the stomach and ovary. We report a case hepatoid carcinoma pancreas developed 41-year-old woman association with pancreatic endocrine The fine needle aspiration material was characterized by presence monotonous, small-to-medium sized tumor cells round nuclei finely granular chromatin, intermixed more...
BACKGROUND Approximately one‐third of patients fail medical treatment for benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) requiring surgical intervention. Our purpose was to establish a molecular characterization undergoing intervention LUTS address therapeutic deficiencies. METHODS Clinical, molecular, histopathological profiles were analyzed in 26 surgery severe LUTS. Incidental transitional zone nodules isolated from 37 with mild radical prostatectomy....
GATA3 is a transcription factor regulating luminal cell differentiation in the mammary glands and has been implicated types of breast carcinoma. The prognostic significance cancer remains controversial.In this study, we assessed value molecule subset 62 advanced cancers 10 control (no metastasis after follow-up).GATA3 expression levels tumors stage were significantly higher than that human epidermal growth receptor 2 (HER2) subtype triple-negative carcinomas, as expected, but similar to...
Abstract Context.—The differential diagnoses of prostatic carcinoma and bladder epithelial neoplasms include several histologic mimics that should be known to avoid misdiagnosis. Objective.—To discuss pseudoneoplastic lesions the prostate could potentially confused with neoplasms, respectively, specific focus on their distinguishing histopathologic features. Data Sources.—Relevant published literature authors' experience. Conclusions.—Pseudoneoplastic in those origin, most common being...