A5072501201- Urological Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Ureteral procedures and complications
- Renal and Vascular Pathologies
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
- Reconstructive Surgery and Microvascular Techniques
- Radiomics and Machine Learning in Medical Imaging
- Renal and related cancers
- Urologic and reproductive health conditions
- Organ Donation and Transplantation
- Testicular diseases and treatments
- Urinary Tract Infections Management
- Tissue Engineering and Regenerative Medicine
- Urinary Bladder and Prostate Research
- Pediatric Urology and Nephrology Studies
- Pelvic floor disorders treatments
- MRI in cancer diagnosis
- Pelvic and Acetabular Injuries
- Sexual Differentiation and Disorders
- Surgical site infection prevention
- Artificial Intelligence in Healthcare and Education
- Vascular anomalies and interventions
Chris O’Brien Lifehouse
2019-2025
University of Southern California
2017-2025
Southern California University for Professional Studies
2025
Royal Prince Alfred Hospital
2015-2024
The University of Sydney
2012-2023
Keck Hospital of USC
2017-2020
Wagga Wagga Base Hospital
2020
Kempten University of Applied Sciences
2019
Seattle University
2019
Westmead Hospital
2014-2016
Artificial intelligence (AI) chatbots, such as ChatGPT, have made significant progress. These particularly popular among health care professionals and patients, are transforming patient education disease experience with personalized information. Accurate, timely is crucial for informed decision-making, especially regarding prostate-specific antigen screening treatment options. However, the accuracy reliability of AI chatbots' medical information must be rigorously evaluated. Studies testing...
Tissue regeneration is limited in several organs including the kidney, contributing to high prevalence of kidney disease globally. However, evolutionary and physiological adaptive responses presence renal progenitor cells suggest existing remodeling capacity. This study uncovered endogenous tissue mechanisms that were activated by loss body fluid salt regulated a unique niche minority cell type called macula densa (MD). Here we identified neuronal differentiation features MD sense local...
To evaluate the impact of indocyanine green (ICG) for assessing ureteric vascularity on rate uretero-enteric stricture formation after robot-assisted radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD).We identified 179 patients undergoing RARC and ICUD between January 2014 May 2017, divided into two groups based utilisation ICG assessment (non-ICG group group). We retrospectively reviewed medical records to identify length ureter excised. Demographic, perioperative...
Since its first description in 1887 by Czerny, partial nephrectomy has undergone significant technical developments and become 'gold standard' treatment of localised RCC [1]. Partial is performed with an open, laparoscopic, or robotic approach depending on patient anatomy, complexity, surgical experience. Minimally invasive approaches have now been demonstrated to similar oncological outcomes [2] compared open surgery; however, they can be limited the difficulty haemostasis. The laparoscopic...
392 Background: Prostate cancer (PCa) remains the second leading cause of death in men. Neoadjuvant pharmacodynamic studies facilitate rational decisions about which therapies should progress to phase 2/3 trials. CDK4/6 inhibitors are effective breast cancer, but have not demonstrated same efficacy metastatic PCa. LEEP assessed effects ribociclib, a highly selective oral inhibitor, hormone-naïve, high-risk, localised Methods: This open-label, window opportunity trial randomised participants...
<title>Abstract</title> <bold>Background</bold>: Curative surgery for prostate cancer is uncommonly offered to patients aged ≥75, balancing functional outcomes against survival benefit. The increased adoption of robotic-assisted radical prostatectomy (RARP) and improved overall life expectancy challenges this paradigm. objective study was compare between elderly younger following RARP. <bold>Methods</bold>: Retrospective review prospective multicentre database including all RARP October 2016...
Objective To evaluate the accuracy of a magnetic resonance imaging (MRI)‐based Likert scoring system in detection clinically significant prostate cancer (CSPC), using MRI/ultrasonography (US) image‐fusion targeted biopsy (FTB) as reference standard. Patients and Methods We retrospectively reviewed 1218 MRI‐detected lesions 629 patients who underwent subsequent MRI/US FTB between October 2012 August 2015. 3‐Tesla MRI was independently reported by one eight radiologists with varying levels...
Although macula densa (MD) cells are chief regulatory in the nephron with unique microanatomical features, they have been difficult to study full detail due their inaccessibility and limitations earlier microscopy techniques. The present used a new mouse model comprehensive imaging approach visualize so far unexplored features of MD cells, regulation, functional relevance. MD-GFP mice conditional partial induction green fluorescent protein (GFP) expression, which specifically intensely...
Objective To assess the diagnostic yield of targeted prostate biopsy in African‐American (A‐A) men using image fusion multi‐parametric magnetic resonance imaging (mp MRI ) with real‐time transrectal ultrasonography ( US ). Patients and Methods We retrospectively analysed 661 patients (117 A‐A 544 Caucasian) who had mp before then underwent / image‐fusion FTB between October 2012 August 2015. The s were reported on a 5‐point Likert scale suspicion. Clinically significant cancer CSPC was...
No AccessJournal of UrologyAdult Urology1 Feb 2021Timing, Patterns and Predictors 90-Day Readmission Rate after Robotic Radical Cystectomy Giovanni E. Cacciamani, Luis Medina, Michael Lin-Brande, Alessandro Tafuri, Ryan S. Lee, Saum Ghodoussipour, Akbar N. Ashrafi, Matthew Winter, Nariman Ahmadi, Nieroshan Rajarubendra, Gus Miranda, Andre De Castro Abreu, Berger, Monish Aron, Inderbir Gill, Mihir Desai CacciamaniGiovanni Cacciamani USC Institute Urology, Keck Medicine USC, University...
We report a case of tumour seeding caused by percutaneous biopsy papillary renal cell carcinoma detected on pathological assessment the partial nephrectomy specimen in 50-year-old male. Whilst masses is considered to be safe and can valuable tool certain lesions, it not without risks. This rare complication should taken into consideration before contemplating its use patient.
To determine the impact of body mass index (BMI) on peri-operative and oncological outcomes after robot-assisted radical cystectomy (RARC) with intracorporeal urinary diversion.A total 216 patients undergoing RARC, extended lymphadenectomy diversion, between July 2010 December 2015, were categorized into four BMI groups according to 2004 World Health Organization obesity classification groups: <25 kg/m2 (normal); 25-29.9 (pre-obese); 30-34.9 (obese class I); ≥35 II). Pre-, intra-...
A refinement to deep inferior epigastric perforator (DIEP) flap harvest that may limit fascial incision length and dissection of the rectus abdominis muscle is by use robotic-assisted surgery (RAS).1 In this technique, sub-muscular portion DIEP pedicle dissected using laparoscopic ports robotic instrumentation. Herein, we present first experience a in Australia New Zealand. 46-year-old female with BRCA1 gene mutation underwent bilateral nipple-sparing mastectomy immediate autologous breast...
Introduction Despite the development of new therapies for advanced prostate cancer, it remains most common cause cancer and second leading death in men. It is critical to develop novel agents treatment particularly those that target aspects androgen receptor (AR) signalling or biology other than inhibition synthesis AR binding. Neoadjuvant pharmacodynamic studies allow a rational approach decisions regarding which targeted should progress phase II/III trials. CDK4/6 inhibitors have evidence...
<b><i>Objectives:</i></b> To evaluate the current accuracy of CT for diagnosing benign renal tumors. <b><i>Materials and Methods:</i></b> We retrospectively reviewed 905 patients who underwent preoperative followed by surgical resection. The final pathology was in 156 (17%). After exclusions, 140 with 163 tumors were included 3 sets interpretations radiologists varying levels experience analyzed. <b><i>Results:</i></b>...
To describe a novel RoboSling technique performed at the time of robot-assisted radical prostatectomy (RARP) and its utility for enhancing urinary function recovery postoperatively.
Abstract Background Australian bladder cancer patients especially women are thought to have worse outcomes when compared the other international series. The objective of this study was assess pathological pattern primary at time radical cystectomy as well assessing quality resection in N ew S outh W ales. Method Pathology reports performed for were reviewed a period 10 years single major pathology centre servicing state Results Two hundred one specimens over years. tumour stage was: CIS 29...