A5044668457- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiovascular Effects of Exercise
- Lipoproteins and Cardiovascular Health
- Cardiac tumors and thrombi
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular and Diving-Related Complications
- Pericarditis and Cardiac Tamponade
- Acute Myocardial Infarction Research
- Takotsubo Cardiomyopathy and Associated Phenomena
- Aortic Disease and Treatment Approaches
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Disease and Adiposity
- Glycogen Storage Diseases and Myoclonus
- Transplantation: Methods and Outcomes
- Platelet Disorders and Treatments
Mayo Clinic in Arizona
2015-2025
Mayo Clinic in Florida
2020-2025
WinnMed
2016-2025
Mayo Clinic Hospital
2022-2024
Mayo Clinic
2015-2024
Creighton University
2024
Minneapolis Heart Institute Foundation
2020-2021
Abbott Northwestern Hospital
2018-2020
University of Cincinnati Medical Center
2012-2015
University of Cincinnati
2011-2015
Tricuspid regurgitation (TR) is a common and progressive valve disease with significant mortality hospitalization burden. transcatheter edge-to-edge repair provides treatment option for high-risk patients primary secondary TR. The TRILUMINATE trial ([Trial to Evaluate Treatment With Abbott Transcatheter Clip Repair System in Patients Moderate or Greater Regurgitation]; n=85) an international, prospective, single-arm, multicenter study investigate the safety performance of tricuspid TriClip...
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy. It follows an autosomal dominant inheritance pattern in cases, with incomplete penetrance and heterogeneity. familial 60% of cases these are caused by pathogenic variants core sarcomeric genes (MYH7, MYBPC3, TNNT2, TNNI3, MYL2, MYL3, TPM1, ACTC1). Genetic testing using targeted disease-specific panels that utilize next-generation sequencing (NGS) include strongest evidence association syndrome-associated highly...
Abstract Aims Lipoprotein(a) [Lp(a)] has demonstrated its association with atherosclerosis and myocardial infarction. However, role in the development of in-stent restenosis (ISR) after percutaneous coronary intervention (PCI) is not clearly established. The aim this study to investigate between Lp(a) ISR. Methods results A retrospective adult patients who underwent successful PCI January 2006 December 2017 at three Mayo Clinic sites had a preprocedural measurement was conducted. Patients...
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Although lipoprotein(a) [Lp(a)] known to be a well-established risk factor for atherosclerotic cardiovascular disease (ASCVD), its role in development of AF, independent this association, remains unclear. Adult patients from three Mayo Clinic sites with baseline Lp(a) and without AF history were included. Patients categorized into two groups based on their levels: high (≥50 mg/dL) low (<50 mg/dL). Survival probabilities free...
To examine differences and similarities in bicuspid aortic valve (BAV) tricuspid (TAV) stenosis occurring during the same age whether any impact outcomes following replacement (AVR). An age-matched cohort of 198 BAV TAV patients was identified from 888 consecutive undergoing AVR for severe AS. Mean 68 ± 6 years; 68% male. Patients with were less likely to have multiple comorbidities, as measured by Charlson Comorbidity Index (CCI) >2 (3 vs. 10%, P = 0.007). Indexed area (0.44 0.09 0.42 0.08...
Lipoprotein(a) [Lp(a)] levels are known to be mainly genetically determined. However, only scarce data available on the intra-individual variability of Lp(a) across time.
Atrial fibrillation (AF) is a low-flow state and may underestimate aortic stenosis (AS) severity. Single-high Doppler signals (HS) consistent with severe AS (peak velocity ≥4 m/s or mean gradient ≥40 mm Hg) are averaged down in current practice. The objective for the study was to determine significance of HS AF low-gradient (LGAS). One thousand five hundred forty-one patients valve area ≤1 cm2 left ventricular ejection fraction ≥50% were identified classified as high-gradient (HGAS) (≥40...
Aims:Increased left ventricular (LV) wall thickness is frequently encountered in transthoracic echocardiography (TTE). While accurate and early diagnosis clinically important, given the differences available therapeutic options prognosis, an extensive workup often required to establish diagnosis. We propose first echo-based, automated deep learning model with a fusion architecture facilitate evaluation of increased thickness. Methods Results: Patients established LV (hypertrophic...