Michelle Ludwig

ORCID: 0000-0001-8860-7269
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About
Contact & Profiles
Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Advanced Radiotherapy Techniques
  • Cervical Cancer and HPV Research
  • Management of metastatic bone disease
  • Advances in Oncology and Radiotherapy
  • Ovarian cancer diagnosis and treatment
  • Breast Cancer Treatment Studies
  • Cancer Risks and Factors
  • Lung Cancer Research Studies
  • Lung Cancer Diagnosis and Treatment
  • Economic and Financial Impacts of Cancer
  • Cancer survivorship and care
  • Glioma Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Treatments and Mutations
  • Brain Metastases and Treatment
  • Multiple and Secondary Primary Cancers
  • Global Cancer Incidence and Screening
  • Thyroid Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • MRI in cancer diagnosis
  • Prostate Cancer Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Prostate Cancer Treatment and Research
  • Effects of Radiation Exposure

Baylor College of Medicine
2016-2025

The University of Texas MD Anderson Cancer Center
2008-2024

The University of Texas Health Science Center at San Antonio
2024

Harris Health System
2022

Smith Clinic
2018-2022

Children's Cancer Center
2015-2021

Radiation Oncology Associates
2020

The University of Texas Health Science Center at Houston
2017-2018

Queen's University
2017

Laser Zentrum Hannover
2013

The most appropriate dose fractionation for whole-breast irradiation (WBI) remains uncertain.To assess acute and 6-month toxic effects quality of life (QOL) with conventionally fractionated WBI (CF-WBI) vs hypofractionated (HF-WBI).Unblinded randomized trial CF-WBI (n = 149; 50.00 Gy/25 fractions + boost [10.00-14.00 Gy/5-7 fractions]) HF-WBI 138; 42.56 Gy/16 [10.00-12.50 Gy/4-5 following breast-conserving surgery administered in community-based academic cancer centers to 287 women 40 years...

10.1001/jamaoncol.2015.2666 article EN JAMA Oncology 2015-08-06

Landmark point-pairs provide a strategy to assess deformable image registration (DIR) accuracy in terms of the spatial underlying anatomy depicted medical images. In this study, we propose augment publicly available database (www.dir-lab.com) images with large sets manually identified anatomic feature pairs between breath-hold computed tomography (BH-CT) for DIR evaluation. Ten BH-CT were randomly selected from COPDgene study cases. Each patient had received CT imaging entire thorax supine...

10.1088/0031-9155/58/9/2861 article EN Physics in Medicine and Biology 2013-04-10

Our objective was to determine whether stereotactic body radiotherapy (SBRT), intensity-modulated radiation therapy (IMRT), and brachytherapy boost techniques have comparable overall survival in treating cervical cancer when adjusted for known prognostic factors.We used the National Cancer Database study women with invasive who were treated between 2004 2013. A logistic regression model built identify factors associated receipt of SBRT IMRT. Outcomes compared using Kaplan-Meier propensity...

10.1097/igc.0000000000001200 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2018-01-11

Female oncologists often spend their childbearing years in training and establishing careers, with many later experiencing fertility issues when starting a family. Physician family planning are rarely discussed during training. Attitudes among female regarding unknown.To understand barriers to as well the association of treatment career decisions assess experiences pregnancy-based discrimination oncologists.In this survey study, novel 39-item questionnaire was distributed US from May 7 June...

10.1001/jamanetworkopen.2022.37558 article EN cc-by-nc-nd JAMA Network Open 2022-10-31

The aim of this study was to quantify the effect four image registration methods on lung texture features extracted from serial computed tomography (CT) scans obtained healthy human subjects.Two chest CT acquired at different time points were collected retrospectively for each 27 patients. Following automated segmentation, follow-up scan registered baseline using algorithms: (1) rigid, (2) affine, (3) B-splines deformable, and (4) demons deformable. accuracy pair evaluated by measuring...

10.1118/1.4730505 article EN Medical Physics 2012-07-16

Radiation therapy is a mainstream strategy in the treatment of several cancer types that are surgically unresectable. Unfortunately, patients often suffer from unintended consequences radiotherapy, including development skin inflammation (dermatitis), which may progress to fibrosis. These morbid complications require interruption radiotherapy and threaten relapse underlying cancer. Current options for radiation dermatitis suboptimal compel need develop safer, more effective therapies. In...

10.1667/rr15398.1 article EN Radiation Research 2019-08-15

Background: Metabolic syndrome has previously been linked to increased risk of endometrial cancer. This study examines the association between metabolic and cancer-specific survival (CSS) in early stage locoregionally advanced Methods: The SEER-Medicare database was used identify a cohort patients with cancer 1992 2011 who underwent hysterectomy. Patients incomplete or grade information were excluded. stratified into (stage I II) III IVa) disease. status determined through Medicare claims 1...

10.1097/coc.0000000000000686 article EN American Journal of Clinical Oncology 2020-03-20

What is known and objective Nephrotoxicity a recognized side effect of cisplatin chemotherapy. However, the optimal strategy for preventing cisplatin-induced nephrotoxicity, if any, remains unclear. The primary this study was to determine whether mannitol or furosemide provides better nephroprotection when administered with hydration prior weekly, low-dose concurrently whole pelvic radiotherapy. Methods Clinical data were abstracted from all women who underwent chemoradiation FIGO IB2-IVA...

10.1111/jcpt.12509 article EN Journal of Clinical Pharmacy and Therapeutics 2017-03-09

The resistance of cancer cells to radiation-based treatment is a major clinical challenge confounding standard care in cancer. This problem particularly notable many solid tumors where are only partially responsive radiation therapy. Combination with radiosensitizers able enhance tumor cell killing. However, currently available associated significant normal tissue toxicity. Accordingly, there an unmet need develop safer and more effective improve control. Here, we evaluated the...

10.18632/oncotarget.28008 article EN Oncotarget 2021-06-24

Radiotherapy affects the functioning of pacemakers. Guidelines based on dosimetric data exist regarding tolerable doses to Little is known about effects radiation implantable drug delivery systems (IDDS). The objective our study evaluate safety treatment delivered patients with IDDS.We evaluated who received external beam therapy in department after implantation an IDDS between January 1, 2000 and November 30, 2011. Information was collected function, goals, fields, prescribed doses,...

10.1111/pme.12037 article EN Pain Medicine 2013-02-21

To evaluate the prognostic significance of hematological toxicities during cervical cancer treatment.Patients treated for carcinoma with definitive chemoradiation were identified. Toxicities assessed weeks 1 to 6 concurrent external beam radiation and chemotherapy. Outcomes analyzed using Cox regression analysis.One hundred twenty-one patients Federation Gynecology Obstetrics stage I-III disease eligible analysis. Median age at diagnosis was 45 years (interquartile range, 40-52) median...

10.5468/ogs.21308 article EN cc-by-nc Obstetrics & Gynecology Science 2022-02-22

Abstract Background Diffusion-weighted magnetic resonance imaging (DWI) provides a measurement of tumor cellularity. We evaluated the potential apparent diffusion coefficient (ADC) values obtained from post-external beam radiation therapy (EBRT) DWI and prior to brachytherapy (BT) predict for complete metabolic response (CMR) in bulky cervical cancer. Methods Clinical (b value = 500 s/mm 2 ) data were patients undergoing interstitial BT with high-risk clinical target volumes (HR-CTVs) >...

10.1186/s13014-024-02425-6 article EN cc-by Radiation Oncology 2024-03-13

This study aims to assess treatment compliance among women undergoing definitive chemoradiation with weekly cisplatin for cervical cancer within a safety net health system and quantify the impact of chemotherapy on outcomes.All who were treated International Federation Gynecology Obstetrics stage IB2 IVA between April 2008 May 2014 identified. Treatment delays attributed toxicity, comorbid conditions, or issues, categorized as patient-initiated. Disease-free survival overall received fewer...

10.1097/igc.0000000000000537 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2015-08-13

Although locally advanced cervical cancer can be cured, patients with stage IVB disease have poor prognosis limited treatment options. Our aim was to describe the pattern of care and analyze health disparity variables that may account for differences in modalities survival this population.The National Cancer Database queried diagnosed between 2004 2013 metastatic squamous cell carcinoma or adenocarcinoma cervix. Codes representing parenchymal lymphatic metastasis (beyond para-aortic...

10.1097/igc.0000000000001264 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2018-05-11
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