A5055400203- Health Systems, Economic Evaluations, Quality of Life
- Economic and Financial Impacts of Cancer
- Central Venous Catheters and Hemodialysis
- Pharmaceutical Economics and Policy
- Colorectal Cancer Screening and Detection
- Statistical Methods in Clinical Trials
- Vascular anomalies and interventions
- Dialysis and Renal Disease Management
- Radiomics and Machine Learning in Medical Imaging
- Helicobacter pylori-related gastroenterology studies
- Cutaneous Melanoma Detection and Management
- Healthcare cost, quality, practices
- Mental Health Treatment and Access
- Vascular Procedures and Complications
- Head and Neck Cancer Studies
- Gastric Cancer Management and Outcomes
- Cancer Genomics and Diagnostics
- CAR-T cell therapy research
- Medical Imaging Techniques and Applications
- Gastroesophageal reflux and treatments
- Glioma Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Treatment of Major Depression
- Global Health Care Issues
- Delphi Technique in Research
Cliniques Universitaires Saint-Luc
2007-2023
UCLouvain
2008-2023
Laboratoire d'Informatique, de Modélisation et d'Optimisation des Systèmes
2020-2023
Faculty of Public Health
2021
Inserm
2012-2013
Bordeaux Population Health
2012-2013
University of Southampton
2011
University of York
2010-2011
Perth Royal Infirmary
2011
Belgian Health Care Knowledge Centre
2004-2008
Encapsulating peritoneal sclerosis (EPS) is a rare but severe complication of dialysis (PD) characterized by extensive fibrosis the peritoneum. Changes in water transport may precede EPS, mechanisms and potential predictive value that defect are unknown. Among 234 patients with ESRD who initiated PD at our institution over 20-year period, 7 subsequently developed EPS. We evaluated changes time on these 28 matched controls using 3.86% glucose equilibration tests. Compared long-term controls,...
Variability in ultrafiltration influences prescriptions and outcomes patients with kidney failure who are treated peritoneal dialysis. Variants AQP1, the gene that encodes archetypal water channel aquaporin-1, may contribute to variability.We gathered clinical genetic data from 1851 dialysis seven cohorts determine whether AQP1 variants were associated a risk of composite death or technique (i.e., transfer hemodialysis). We performed studies cells, mouse models, samples obtained humans...
Objectives: The increasing use of full economic evaluations has led to the development various instruments assess their quality. purpose this study was compare frequently used British Medical Journal (BMJ) check-list and two new instruments: Consensus Health Economic Criteria (CHEC) list Quality Studies (QHES) instrument. analysis based on a practical exercise surgical treatment obesity. Methods: quality nine selected studies assessed independently by health economists. To instruments,...
Abstract BACKGROUND. The study aimed to compare the cost‐effectiveness of concomitant and adjuvant temozolomide (TMZ) for treatment newly diagnosed glioblastoma multiforme versus initial radiotherapy alone from a public health care perspective. METHODS. economic evaluation was performed alongside randomized, multicenter, phase 3 trial. primary endpoint trial overall survival. Costs included all direct medical costs. Economic data were collected prospectively subgroup 219 patients (38%). Unit...
Most guidelines consider FDG PET-CT to detect occult extra-pulmonary disease prior lung metastasectomy. A cost-effectiveness analysis, using a Markov model over 10 year period, was performed compare two different surveillance programs, either or whole-body CT, in patients with suspected pulmonary metastasised melanoma.Data from published studies provided probabilities for the model. Complication and care costs were obtained standardised administrative databases 19 hospitals identified by DRG...
Although superior vena cava (SVC) stenosis may be a life-threatening complication of haemodialysis (HD) catheters, its prevalence and risk factors in HD patients are unknown. Our aim was to assess the for SVC with tunnelled cuffed catheter (TCC) describe clinical presentation.In this single-centre, retrospective cohort study, all in-centre chronic carrying TCC (1 January 2008-31 December 2012) were included (n = 117 patients, 214 TCC, 80 911 catheter-days). defined as diameter reduction >50%...
Fat accumulation in skeletal muscle was recently established as a major risk factor for cardiovascular disease (CVD) the general population, but its relevance patients with kidney failure is unknown. Here we examined potential association between radiation attenuation (MRA), non-invasive indicator of fat deposits muscle, and events treated peritoneal dialysis (PD) investigated dynamic changes determinants MRA this population. We retrospectively assessed on computed tomography images...
BACKGROUND: Colonoscopy has become accepted as one of the most effective methods screening patients for colorectal cancer, and is used to remove majority colonic adenomas. OBJECTIVE: Because paucity such estimates in literature significant number candidates this procedure, present study was performed estimate direct hospital costs both diagnostic therapeutic (polypectomy) colonoscopy. METHODS: A microcosting methodology itemize Variable fixed were divided into labour, supplies, equipment...
OBJECTIVES: To assess the association between selected physician characteristics and suboptimal duration of antidepressant use in older outpatient population. DESIGN: Follow‐up patients who were prescribed an treatment by a cohort physicians Quebec. SETTING: Community‐based population PARTICIPANTS: Retrospective 1,301 general practitioners (GPs) 236 psychiatrists followed from 1991 to 1997. MEASUREMENTS: Treatment less than 180 days 1996/97. RESULTS: Premature interruption was very frequent...
Chronic pancreatitis may lead to steatorrhea, enteric hyperoxaluria, and kidney damage. However, the prevalence determinants of hyperoxaluria in chronic patients as well its association with renal function decline have not been investigated. We performed an observational study. Urine oxalate creatinine ratio was assessed on 2 independent random urine samples consecutive adult followed at outpatient clinic from March 1 October 31, 2012. Baseline characteristics annual estimated glomerular...
Several mapping or cross-walking algorithms for deriving utilities from the European Organisation Research and Treatment of Cancer Quality Life Questionnaire (EORTC QLQ-C30) scores have been published in recent years. However, large majority used ordinary least squares (OLS) regression, which proved to be not very accurate because specifics quality-of-life measures.Our objective was compare regression methods that map EuroQol 5 Dimensions 3 Levels (EQ-5D-3L) utility values general EORTC...