- Palliative Care and End-of-Life Issues
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Patient Dignity and Privacy
- Global Cancer Incidence and Screening
- Frailty in Older Adults
- Cancer Treatment and Pharmacology
- Colorectal Cancer Screening and Detection
- Pancreatic and Hepatic Oncology Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Geriatric Care and Nursing Homes
- Multiple and Secondary Primary Cancers
- Family and Patient Care in Intensive Care Units
- Telemedicine and Telehealth Implementation
- Prostate Cancer Treatment and Research
- Family Support in Illness
- Venous Thromboembolism Diagnosis and Management
- Chemotherapy-related skin toxicity
- Advances in Oncology and Radiotherapy
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Genetic factors in colorectal cancer
- Pain Management and Opioid Use
University of Pennsylvania
2021-2025
University of Pennsylvania Health System
2021-2025
Abramson Cancer Center
2021-2025
Penn Center for AIDS Research
2021-2024
University of Rochester Medical Center
2023
Loma Linda University
2023
Sidney Kimmel Comprehensive Cancer Center
2019-2022
Mayo Clinic Hospital
2022
Einstein Medical Center Philadelphia
2020-2022
Johns Hopkins University
2019-2021
Background Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B ) is a putative tumor suppressor, and preliminary evidence suggests LRP1B- mutated cancers may have improved outcomes with immune checkpoint inhibitors (ICI). Methods We conducted multicenter, retrospective pan-cancer analysis of patients alterations treated ICI at Duke University, Johns Hopkins University (JHU) Michigan (UM). The primary objective was to assess the association between overall response rate...
Chemotherapy-Induced Peripheral NeuropathyPeripheral neuropathy refers to symptoms arising from damage peripheral nerves.These nerves carry sensation, control movements of the arms and legs, bladder bowel.Chemotherapy other drugs used treat cancer can cause neuropathy.This is termed chemotherapy-induced (or CIPN).
Frequent visits to health care facilities can be time intensive and all-consuming for people with cancer. We measured contact days (days healthcare outside the home) among decedents advanced GI cancer examined sources of days, their associations demographic clinical factors, temporal patterns over course illness.
Abstract While digital health solutions continue to grow in number and complexity, the ability for stakeholders healthcare easily discern quality lags far behind. This challenge is part due lack of a transparent standardized approach validation. Evaluation mobile applications (apps) further burdened by low barriers development direct-to-user marketing, leading crowded confusing landscape. In this context, we investigated pragmatic application previously described framework validation,...
Importance Among patients with advanced solid malignant tumors, early specialty palliative care (PC) is guideline recommended, but strategies to increase PC access and effectiveness in community oncology are lacking. Objective To test whether algorithm-based defaults opting out accountable justification embedded the electronic health record (EHR) completed visits. Design, Setting, Participants This 2-arm cluster randomized clinical trial was conducted from November 1, 2022, December 31,...
Substantial gaps in national healthcare spending and disparities cancer mortality rates are noted across counties the US. In this cross-sectional analysis, we investigated whether differences local county-level social vulnerability impacts cancer-related mortality. We linked age-adjusted (AAMR) from Centers for Disease Control Prevention (CDC) Wide-ranging Online Data Epidemiologic Research database, to Social Vulnerability Index (SVI) CDC Agency Toxic Substances Registry. SVI is a metric...
The integration of palliative care into routine oncology practice is the standard by most leading cancer organizations. Palliative medicine helps to deliver higher quality at a lower cost. However, there are barriers implementing many institutions for myriad reasons. In this article, we discuss an innovative strategy that ASCO implemented called Communities Practice (CoP). We share our experiences as Care CoP and how group seeks develop processes structures collectively promote systemic...
African American patients with cancer underutilize advance care planning (ACP) and palliative (PC). This feasibility study investigated whether community health workers (CHWs) could improve ACP PC utilization for advanced cancer.
This commentary discusses evidence supporting the importance of full palliative care dose intensity in outcomes for patients with cancer.
Over 62,000 U.S. adults will be diagnosed with pancreatic cancer in 2022 [1]. The median age at diagnosis is 71 years, and by 2030, 70% of occur older [2,3]. Almost 90% patients report least one moderate-to-severe symptom (score ≥4 on a 0–10 self-reported scale) [4]. These symptoms frequently cluster together, are persistent through the course illness Patients may experience due to itself (e.g., pain) or its treatment chemotherapy-induced peripheral neuropathy) [5].
To decrease the financial burden on people with cancer, clinicians and patients increasingly use medication price comparison websites to seek pharmacies where medications may be cheaper. Shopping around at different can add additional time logistic care partners. We sought determine whether a single pharmacy consistently offered lowest for symptom control medications.We compiled medications/formulations used manage two common cancer-associated symptoms: nausea/vomiting anorexia/cachexia....
Ascites, or Fluid in the Belly, Patients With CancerWhat Is Ascites?Ascites (uh-SIGH-tees) refers to excess fluid abdomen.This collects space within walls of abdomen, between abdominal organs.It is common patients with liver disease and cirrhosis, though cancer can also develop ascites.