A5069112037- Malaria Research and Control
- vaccines and immunoinformatics approaches
- Liver Disease Diagnosis and Treatment
- Natural Antidiabetic Agents Studies
- Infectious Diseases and Mycology
- Invertebrate Immune Response Mechanisms
- Mycobacterium research and diagnosis
- Viral Infections and Vectors
- Microbial infections and disease research
- Autophagy in Disease and Therapy
- Cannabis and Cannabinoid Research
- Food Science and Nutritional Studies
- Polymer Synthesis and Characterization
- Liquid Crystal Research Advancements
- Analytical Methods in Pharmaceuticals
- Animal Disease Management and Epidemiology
- Psychedelics and Drug Studies
- Vector-Borne Animal Diseases
- Monoclonal and Polyclonal Antibodies Research
- Tuberculosis Research and Epidemiology
- Various Chemistry Research Topics
- Peroxisome Proliferator-Activated Receptors
- Advanced Materials and Mechanics
- RNA Interference and Gene Delivery
- Essential Oils and Antimicrobial Activity
The University of Queensland
2020-2024
CSIRO Health and Biosecurity
2024
Commonwealth Scientific and Industrial Research Organisation
2024
Australian Centre for Disease Preparedness
2024
Health Sciences and Nutrition
2024
Southeast University
2015-2017
Jahangirnagar University
2015
Neurochemistry refers to the chemical processes that occur in brain and nervous system. This section of study determines how neurochemicals influence network neural operation. The transfers numerous information via neurons communicate. main role neurochemistry activities takes place brain, which allows it perform actions. Foundation is a little bit different from man several things can play levels various neurotransmitters brain. It supposed differences chemistry may accountable for variety...
Subunit vaccines require an immunostimulant (adjuvant) and/or delivery system to induce immunity. However, currently, available adjuvants are either too dangerous in terms of side effects for human use (experimental adjuvants) or have limited efficacy and applicability. In this study, we examined the capacity mannose-lipopeptide ligands enhance immunogenicity a vaccine consisting polyleucine(L15)-antigen conjugates anchored liposomes. The clinically tested Group A Streptococcus (GAS) B-cell...
<title>Abstract</title> Buruli ulcer (BU) is a necrotizing disease of skin and soft tissue caused by the bacterium <italic>Mycobacterium ulcerans </italic>(MU). In Australia, where spreading case numbers increasing, native possum species act as reservoir hosts. To better understand life history MU in one its natural hosts, we conducted intra-dermal challenge six wild caught, MU-naïve common ringtail possums (<italic>Pseudocheirus peregrinus</italic>). All animals developed BU consistent with...
Infection with malaria parasites continues to be a major global public health issue. While current control measures have enabled significant decrease in morbidity and mortality over the last 20 years, additional tools will required if we are progress toward parasite eradication. Malaria vaccine research has focused on development of subunit vaccines; however, more recently, interest whole-parasite vaccines reignited. Whole-parasite enable presentation broad repertoire antigens immune system,...
Amphetamines are central nervous system (CNS) stimulants and belong to psychoactive drugs that affect chemicals in the brain, nerves exert a constant contribution hyperactivity impulse control. The communal group of amphetamines comprises amphetamine, dextroamphetamine methamphetamine. show its action on mesolimbic dopaminergic reward by inducing release dopamine some extent norepinephrine, synaptic clefts nucleus accumbens other terminal areas. They offer not only sense euphoric state, but...
Buruli ulcer (BU) is a necrotizing disease of skin and soft tissue caused by the bacterium Mycobacterium ulcerans (MU). In Australia, where emerging in new geographic areas human case numbers are increasing, native possum species act as reservoir hosts. To better understand life history MU one its natural hosts, we conducted intra-dermal challenge six wild caught, MU-naïve common ringtail possums (Pseudocheirus peregrinus). All animals developed BU consistent with that observed naturally...
Autophagy is an intracellular catabolic system by which cells degrade and recycle cytoplasmic constituents such as organelles proteins through the lysosome-dependent path.Belgian biochemist, Christian de Duve coined name "autophagy" in 1963.The identification of autophagy-related genes finally discoveries mechanisms for autophagy led to award 2016 Nobel Prize Medicine or Physiology Japanese cell biologist, Yoshinori Ohsumi specializing autophagy.Autophagy shows a crucial role removing...
In recent years, the popularity of medicinal plants as a remedy has been increased manifold due to having minimal adverse effects. The current study aimed compare hypoglycemic, hypolipidemic and hepatoprotective effects ethanolic extract Asparagus racemosus (EEAR) Linn. alone combinedly with conventional antidiabetic agents (gliclazide pioglitazone) in alloxan-induced diabetic rats. Diabetes was induced male Wister albino rats by administration single intra-peritoneal injection alloxan...
The aim of this present work is to investigate the antimicrobial, antioxidant and cytotoxic activities methanol extract Polygonum orientale (Family: Polygonaceae). Antimicrobial activity was tested by Disc Diffusion Method. Standard antibiotic discs Kanamycin (30µg/disc) for bacterial species used as standard crude extracts were at a concentration (20mg/disc) (40mg/disc) leaves (10mg/disc) shoot extracts. shoots showed mild against gram positive bacteria, negative bacteria fungi. Most...
Background and Objectives: The present study was designed to investigate the hypoglycemic, hypolipidemic hepatoprotective activity of fixed dose combination pioglitazone fenofibrate.Methodology: For purpose, at a 15 mg/70 kg b.wt.and fenofibrate 72.5 b.wt., were administered on alloxan (120 mg kgG 1 b.wt.) induced diabetic rats.Both drugs (pioglitazone fenofibrate), singly in combination, separately tested vivo for 14 days determine blood glucose level, lipid profile using Long-Evans male...
Background and Objective: Combination of dosages regimen an antidiabetic agent (Glibenclamide) with a lipid lowering drug can be effective medication for the patient high blood glucose level liver enzyme disfunctionality.The present study was undertaken to investigate effect fixed dose combination glibenclamide (1.2 mg/70 kg b.wt.) simvastatin (10 on enzymes dysfuntionality in alloxan-induced diabetic rats extended time period.Materials Methods: Two protocols were developed carry out...
Malaria is a vector born parasitic disease causing millions of deaths every year. Despite the high mortality rate, an effective vaccine against this mosquito-borne infectious yet to be developed. Up date, RTS,S/AS01 only available for malaria prevention; however, its efficacy low. Among variety antigens, merozoite surface protein-1(MSP-1) and ring-infected erythrocyte antigen (RESA) have been proposed as promising candidates development. We developed peptide-based Plasmodium falciparum that...