A5081233132- Natural Antidiabetic Agents Studies
- Phytochemical compounds biological activities
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Ethnobotanical and Medicinal Plants Studies
- Plant tissue culture and regeneration
- Chemical synthesis and alkaloids
- Heavy Metal Exposure and Toxicity
- Alzheimer's disease research and treatments
- Phytochemistry and Biological Activities
- Pineapple and bromelain studies
- Diet, Metabolism, and Disease
- Phytochemicals and Medicinal Plants
- Saffron Plant Research Studies
- COVID-19 Clinical Research Studies
- Nanoparticle-Based Drug Delivery
- Curcumin's Biomedical Applications
- Medicinal Plants and Neuroprotection
- Antioxidant Activity and Oxidative Stress
- Phytochemistry and Bioactive Compounds
- Parkinson's Disease Mechanisms and Treatments
- Mitochondrial Function and Pathology
- Moringa oleifera research and applications
- Free Radicals and Antioxidants
Jadavpur University
2016-2025
Adamas University
2024
Copperbelt University
2024
Advanced Pharma
2010-2023
Indian Institute of Chemical Technology
2021
University of Lisbon
2012-2013
University of Benin
2007
University of Miami
1991
Abstract The production and release of tumor-derived small extracellular vesicles (TDSEVs) from cancerous cells play a pivotal role in the propagation cancer, through genetic biological communication with healthy cells. TDSEVs are known to orchestrate invasion-metastasis cascade via diverse pathways. Regulation early metastasis processes, pre-metastatic niche formation, immune system regulation, angiogenesis initiation, matrix (ECM) remodeling, modulation, epithelial-mesenchymal transition...
Alzheimer's disease (AD) is a very common neurodegenerative disorder associated with memory loss and progressive decline in cognitive activity. The two major pathophysiological factors responsible for AD are amyloid plaques (comprising amyloid-beta aggregates) neurofibrillary tangles (consisting of hyperphosphorylated tau protein). Polyphenols, class naturally occurring compounds, immensely beneficial the treatment or management various disorders illnesses. Naturally sources polyphenols...
Abroma augusta L. (Malvaceae) leaf is traditionally used to treat diabetes in India and Southern Asia. Therefore, current study was performed evaluate the protective effect of defatted methanol extract A. leaves (AA) against type 2 mellitus (T2DM) its associated nephropathy cardiomyopathy experimental rats.Antidiabetic activity AA extracts (100 200 mg/kg, p.o.) measured streptozotocin-nicotinamide induced diabetic (T2D) rat. Fasting blood glucose level (at specific interval) serum...
The present investigation was executed to reveal the protective mechanism of rosmarinic acid (RA) against cadmium (Cd)-induced nephrotoxicity. RA exhibited a concentration-dependent anti-apoptotic effect CdCl2 in isolated mouse proximal tubular epithelial cells. Cd treatment significantly (p < 0.01) imparted oxidative stress renal cells via excessive ROS production, triggering NO level, NADPH oxidase activation, and impairment cellular redox defense system. Cd-mediated endorsed apoptosis...
Garcinol (GAR) is a naturally occurring polyisoprenylated phenolic compound. It has been recently investigated for its biological activities such as antioxidant, anti-inflammatory, anti ulcer, and antiproliferative effect on wide range of human cancer cell lines. Though the outcomes are very promising, extreme insolubility in water remains main obstacle clinical application. Herein we report formulation GAR entrapped PLGA nanoparticles by nanoprecipitation method using vitamin E TPGS an...
Persistent hyperglycemia, impairment of redox status and establishment inflammatory pathophysiology integrally play important role in the pathogenesis diabetic cardiomyopathy (DC). Present study examined therapeutic potential protocatechuic acid isolated from Sansevieria roxburghiana rhizomes against DC employing rodent model type 2 diabetes (T2D). T2D was induced by high fat diet + a low-single dose streptozotocin (35 mg/kg, i.p.). rats exhibited significantly (p < 0.01) fasting blood...