- Sepsis Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Health Systems, Economic Evaluations, Quality of Life
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Pharmaceutical Economics and Policy
- Antibiotic Use and Resistance
- Hemodynamic Monitoring and Therapy
- Traumatic Brain Injury and Neurovascular Disturbances
- Parathyroid Disorders and Treatments
- Palliative Care and End-of-Life Issues
- Viral Infections and Immunology Research
- Healthcare cost, quality, practices
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Nosocomial Infections in ICU
- Family and Patient Care in Intensive Care Units
- Pneumonia and Respiratory Infections
- Abdominal Trauma and Injuries
- Electrolyte and hormonal disorders
- Schizophrenia research and treatment
- Folate and B Vitamins Research
- Traumatic Brain Injury Research
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
Mario Negri Institute for Pharmacological Research
2014-2025
University of Florence
2018
Ospedale di Mirano
2015
PAREXEL International (United Kingdom)
2011-2013
Cone Health
2013
Università Cattolica del Sacro Cuore
2008
University of Bergamo
2005
Sapienza University of Rome
2005
University of Perugia
2005
Takayasu's arteritis (TA) is a rare vasculitis. The Italian Arteritis study group was established with the aim to describe large cohort of patients.Data were collected by means an ad hoc form. Demographic information, clinical history, vascular findings, treatment, risk factors, and comorbidities analyzed.Data 104 patients collected. median delay in diagnosis 15.5 months (range 0-325 months). Age at onset <15 years associated higher probability, whereas elevated erythrocyte sedimentation...
Mortality is high among patients with hematologic malignancies admitted to intensive care units for acute respiratory failure. Early noninvasive mechanical ventilation seems improve outcomes.To characterize use in Italian failure and its impact on outcomes vs. invasive ventilation.Retrospective analysis of observational data prospectively collected 2002-2006 1,302 158 units.Mortality (intensive unit hospital) was assessed treated initially those ab initio after Findings were adjusted...
Objectives Coupled plasma filtration adsorption (CPFA, Bellco, Italy), to remove inflammatory mediators from blood, has been proposed as a novel treatment for septic shock. This multicenter, randomised, non-blinded trial compared CPFA with standard care in the of critically ill patients Design Prospective, open-label, two parallel group and superiority clinical trial. Setting 18 Italian adult, general, intensive units (ICUs). Participants Of planned 330 adult shock, 192 were randomised...
While the relationship between persistent elevations in intracranial pressure (ICP) and poorer outcomes is well established for patients with traumatic brain injury (TBI), there no consensus on how ICP measurements should drive treatment choices, effectiveness of monitoring remains unknown.To evaluate short- mid-term TBI.CREACTIVE was a prospective cohort study that started March 2014 lasted 5 years. More than 8000 TBI were enrolled at 83 intensive care units (ICUs) from 7 countries who...
<h3>Objective:</h3> Paraneoplastic neurological syndromes (PNS) probably result from an immune reaction against antigens shared by the nervous system and tumour cells. To characterise CSF alterations in these syndromes, we studied a large series of paraneoplastic patients. <h3>Methods:</h3> Using PNS European database which includes patients diagnosed with Europe, reviewed clinical data all included between 2000 2007 for information on was available. Patients were if they met following...
Abstract Background Cross‐sectional studies have shown that chronic musculoskeletal pain and somatic symptoms are frequently reported by sexual assault ( SA ) survivors; however, prospective examining in the months after not been performed. Methods Women survivors 18 years of age or older who presented for care within 48 h were recruited. Pain eight body regions (head face, neck, breast, arms, abdomen, back, genital pelvic, legs) 21 common (e.g., headache, nausea, insomnia, persistent...
To prospectively assess the use of antibiotics in ICUs.A total 979 critically ill patients over 14 years age were recruited 43 Italian ICUs. For each patient, admission and discharge characteristics, information on drugs administered, antibiotic susceptibility tests (ASTs), presence severity sepsis collected daily until or for a maximum 21 days.Most with (99%) received antibiotics, almost all (93%) treatment was started empirically, broad-spectrum antibiotics. ASTs followed onset empirical...
Long-lasting shared research databases are an important source of epidemiological information and can promote comparison between different healthcare services. Here we present PROSAFE, advanced international network in intensive care medicine, with the focus on assessing improving quality care. The project involved 343 ICUs seven countries. All patients admitted to ICU were eligible for data collection.The PROSAFE collected using same electronic case report form translated into corresponding...
To establish the effectiveness of ICU treatment and efficiency in use resources patients stratified according to 10 diagnosis two levels-of-care. propose strategies aimed at reducing costs improving each patient group.Multicentre prospective observational study. ICUs enrolled cohorts up consecutive with stay >/= 48 h. Each one these diagnoses: trauma, brain-trauma, brain-hemorrhage, stroke, acute-on-chronic-obstructive-pulmonary disease, lung-injury/acute respiratory distress syndrome, heart...