Pengxiang Zheng

ORCID: 0000-0001-9134-4340
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About
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Research Areas
  • Natural Compounds in Disease Treatment
  • Retinopathy of Prematurity Studies
  • Ocular Diseases and Behçet’s Syndrome
  • Innovations in Medical Education
  • Pneumonia and Respiratory Infections
  • Marine Biology and Ecology Research
  • RNA Research and Splicing
  • Enzyme function and inhibition
  • Cancer-related gene regulation
  • Nosocomial Infections in ICU
  • Particle Detector Development and Performance
  • Atrial Fibrillation Management and Outcomes
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Biochemical and Molecular Research
  • Acute Myocardial Infarction Research
  • Health and Medical Research Impacts
  • Medical and Biological Sciences
  • Coastal wetland ecosystem dynamics
  • Marine and coastal plant biology
  • Enzyme Structure and Function
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Ocular Surface and Contact Lens
  • Coronary Interventions and Diagnostics
  • Cardiac Imaging and Diagnostics

Shanghai Ocean University
2023

Fujian Institute of Oceanography
2023

Ministry of Natural Resources
2023

Jinling Institute of Technology
2023

Yangpu Hospital of Tongji University
2009-2022

OBJECTIVE: Glioblastoma multiforme is the most frequent primary brain tumor in adults. The major obstacle for successful treatment invasive growth pattern. Metabolically, glioblastomas are highly glycolytic, leading to increased levels of lactic acid production. carbonic anhydrase IX (CAIX) moderates extrusion hydrogen ions into extracellular space, which may enhance invasion by activating proteolytic enzymes. We therefore induced glycolysis glioblastoma cells and investigated pH, cathepsin...

10.1093/neuonc/nos219 article EN Neuro-Oncology 2012-10-01

Retinopathy of prematurity (ROP), which is characterized by retinal neovascularization (RNV), a major cause neonatal blindness. The primary treatment for ROP anti-vascular endothelial growth factor (VEGF) therapy, costly and can rapidly lead to desensitization. Celastrol, bioactive compound extracted from Tripterygium wilfordii Hook F. ("Thunder God Vine"), has been shown exert anticancer anti-inflammatory effects. However, whether celastrol antiangiogenic activity suppress inflammation...

10.1080/15384101.2022.2087277 article EN Cell Cycle 2022-06-13

Atrial fibrillation (AF) is the most common form of sustained cardiac arrhythmia responsible for substantial morbidity and significantly increased mortality rates. A growing body evidence documents important role genetic defects in pathogenesis AF. However, AF a heterogeneous disease determinants an overwhelming majority patients remain unknown. In present study, cohort 100 unrelated with lone total 200 unrelated, ethnically matched healthy individuals used as controls, were recruited. The...

10.3892/ijmm.2013.1463 article EN International Journal of Molecular Medicine 2013-08-02

We aimed to investigate the symptoms of dry eye disease (DED) hospitalized patients with coronavirus 2019 (COVID-19).This cross-sectional, observational study analysis included 91 confirmed COVID-19 in Wuhan, China. The Ocular Surface Disease Index (OSDI) and five-item Dry Eye Questionnaire (DEQ-5) were used assess severity DED patients, variance was determine factors associated DED.A total 42 consented complete investigation (response rate 46.15%). There 26 (61.90%) who diagnosed by OSDI,...

10.1155/2021/2678706 article EN cc-by Journal of Ophthalmology 2021-12-08

Abstract 20-inch Large area photomultiplier tube based on microchannel plate (MCP-PMT) is newly developed in China. It widely used high energy detection experiments such as Jiangmen Underground Neutrino Observatory (JUNO), China JinPing underground Laboratory (CJPL) and High Altitude Air Shower (LHAASO). To overcome the poor time performance of existing MCP-PMT, a new design large MCP-PMT proposed this paper. Three-dimensional models are CST Studio Suite to validate its feasibility. Effects...

10.1038/s41598-023-47818-x article EN cc-by Scientific Reports 2023-11-22

This paper analyzed the exogenous and endogenous resource elements in a view of their supportive effect on construction development clinical disciplines, proposed relationship between two resources , provided references to disciplines by elaborating specific content focus these elements. Key words: Clinical disciplines; Exogeneous resources; Endogeneous

10.3760/cma.j.issn.1006-1924.2016.03.017 article EN Zhonghua yixue keyan guanli zazhi 2016-06-21
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