Yihui Chen
- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Aortic aneurysm repair treatments
- Glaucoma and retinal disorders
- Aortic Disease and Treatment Approaches
- Photodynamic Therapy Research Studies
- Liver Disease Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Wound Healing and Treatments
- Retinal Diseases and Treatments
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Diabetic Foot Ulcer Assessment and Management
- Epigenetics and DNA Methylation
- Venous Thromboembolism Diagnosis and Management
- Infectious Aortic and Vascular Conditions
- Surgical Sutures and Adhesives
- Retinal and Optic Conditions
- Cancer, Hypoxia, and Metabolism
- Hepatitis B Virus Studies
- Burn Injury Management and Outcomes
- Hepatitis C virus research
- Genetic and Kidney Cyst Diseases
- Exercise and Physiological Responses
Yangpu Hospital of Tongji University
2021-2024
Zhongshan Hospital of Xiamen University
2018-2024
Fudan University
2018-2024
Central South University
2024
Xiangya Hospital Central South University
2024
Nanchang University
2024
Tongji University
2024
Jiaxing University
2024
Institute of High Energy Physics
2015-2023
Hunan University
2021
A carrier-free method for delivery of a hydrophobic drug in its pure form, using nanocrystals (nanosized crystals), is proposed. To demonstrate this technique, photosensitizing anticancer drug, 2-devinyl-2-(1-hexyloxyethyl)pyropheophorbide (HPPH), have been synthesized the reprecipitation method. The resulting were monodispersed and stable aqueous dispersion, without necessity an additional stabilizer (surfactant). As shown by confocal microscopy, these taken up cancer cells with high...
Abstract The search for effective combination therapies cancer has focused heavily on synergistic combinations because they exhibit enhanced therapeutic efficacy at lower doses. Although synergism is intuitively attractive, success often depends whether drug resistance develops. impact of (vs. antagonistic or additive combinations) the process drug-resistance evolution not been investigated. In this study, we use a simplified computational model cell numbers in population drug-sensitive,...
The Born cross-sections and effective form factors for process $e^+e^-\to\Xi^-\bar{\Xi}^+$ are measured at eight center-of-mass energies between 2.644 3.080 GeV, using a total integrated luminosity of 363.9 pb$^{-1}$ $e^+e^-$ collision data collected with the BESIII detector BEPCII. After performing fit to cross-section $e^+e^-\to\Xi^-\bar{\Xi}^+$, no significant threshold effect is observed.
This study utilizes machine learning to analyze the recurrence risk of diabetic foot ulcers (DFUs) in elderly patients, aiming enhance prevention and intervention efforts.
Using $e^+e^-\to\Lambda_c^+\bar\Lambda_c^-$ production from a 567 pb$^{-1}$ data sample collected by BESIII at 4.6 GeV, full angular analysis is carried out simultaneously on the four decay modes of $\Lambda_c^+\to pK_S^0$, $\Lambda \pi^+$, $\Sigma^+\pi^0$, and $\Sigma^0\pi^+$. For first time, $\Lambda_c^+$ transverse polarization studied in unpolarized $e^+e^-$ collisions, where non-zero effect observed with statistical significance 2.1$\sigma$. The asymmetry parameters weak hadronic decays...
Abstract Background: Thoracic aortic aneurysm (TAA) is a fatal cardiovascular disease, the pathogenesis of which has not yet been clarified. This study aimed to identify and validate diagnostic markers TAA provide strong theoretical basis for developing new methods prevent treat this disease. Methods: Gene expression profiles GSE9106, GSE26155, GSE155468 datasets were acquired from Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) identified using "limma" package in R....
Using a data sample of 106 million $\ensuremath{\psi}(3686)$ events collected with the BESIII detector operated at BEPCII storage ring, we study for first time decays ${\ensuremath{\chi}}_{cJ}\ensuremath{\rightarrow}\ensuremath{\phi}{K}_{S}^{0}{K}^{\ifmmode\pm\else\textpm\fi{}}{\ensuremath{\pi}}^{\ensuremath{\mp}}$ and ${\ensuremath{\chi}}_{cJ}\ensuremath{\rightarrow}\ensuremath{\phi}{K}^{+}{K}^{\ensuremath{-}}{\ensuremath{\pi}}^{0}$ in E1 radiative transition...
Using a data sample of $1.31 \times 10^{9}$ $J/\psi$ events accumulated with the BESIII detector, decay $J/\psi\to p\bar{p}\phi$ is studied via two modes, $\phi\to K^{0}_{S}K^{0}_{L}$ and K^{+}K^{-}$. The branching fraction measured to be $\mathcal{B}(J/\psi\to p\bar{p}\phi)=[5.23\pm0.06(\mbox{stat})\pm0.33(\mbox{syst})]\times10^{-5}$, which agrees well previously published measurement, but significantly improved precision. No evident enhancement near $p\bar{p}$ mass threshold, denoted as...
<title>Abstract</title> Background The proportion of hypertriglyceridemic acute pancreatitis (HTG-AP) in is increasing year by year. risk AP occurrence and recurrence positively related to triglyceride levels. At present, the application therapeutic plasma exchange (TPE) HTG-AP gradually popularized, but there no consensus on whether it can improve mortality prognosis HTG-AP. Therefore, we aimed compare differences between TPE conventional therapy treatment Methods Our study collected nearly...
Laser therapy has been proven as an effective technique for managing ophthalmological disorders. To guide future research, we conducted a bibliometric analysis of laser applications in eye diseases from 1990 to 2022, aiming identify key themes and trends.
To report the experience of a single centre regarding application triple-chimney technique using C-TAG with Viabahn or Excluder iliac extension devices for endovascular management aortic arch dilation diseases.From July 2016 to August 2017, 7 patients (5 men; mean age 56.1±10.8 years) diseases were treated technique. All followed up at 1, 3, and 6 months every thereafter.Six innominate arteries deployed extensions one cover-stent. left common carotid subclavian placed Viabahn. Reverse...
Based on $448.1 \times 10^6$ $\psi(3686)$ events collected with the BESIII detector, decays $\psi(3686)\to\gamma\chi_{cJ}, \chi_{cJ} \to \gamma\gamma~(J=0, 1, 2)$ are studied. The decay branching fractions of $\chi_{c0,c2} \gamma\gamma$ measured to be $\mathcal{B}(\chi_{c0}\to\gamma\gamma) = (1.93 \pm 0.08 0.05 0.05)\times 10^{-4}$ and $\mathcal{B}(\chi_{c2}\to\gamma\gamma) (3.10 0.09 0.07 0.11)\times 10^{-4} $, which correspond two-photon widths $\Gamma_{\gamma\gamma}(\chi_{c0}) 2.03 0.06...
Abstract Oral Squamous Cell Carcinoma (OSSC) is a major life‐threatening disease with high incidence in the Southeast Asian countries. Chronic exposure to arecoline causes genetic changes epithelial cells of oral mucosa, induces proliferation through activation EGF receptor and promotes downstream COX‐2 expression. Taiwanin C, podophyllotoxin derived from Taiwania cryptomerioides Hayata known inhibit COX activity hinder PGE2 production macrophages. In this study tumor cell line T28 non‐tumor...
A bstract Using a data set corresponding to an integrated luminosity of 6.32 fb − 1 recorded by the BESIII detector at center-of-mass energies between 4.178 and 4.226 GeV, amplitude analysis decay $$ {D}_s^{+} <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msubsup> <mml:mi>D</mml:mi> <mml:mi>s</mml:mi> <mml:mo>+</mml:mo> </mml:msubsup> </mml:math> → π + 0 is performed, relative fractions phases different intermediate processes are determined. The absolute branching fraction...
We aimed to investigate the symptoms of dry eye disease (DED) hospitalized patients with coronavirus 2019 (COVID-19).This cross-sectional, observational study analysis included 91 confirmed COVID-19 in Wuhan, China. The Ocular Surface Disease Index (OSDI) and five-item Dry Eye Questionnaire (DEQ-5) were used assess severity DED patients, variance was determine factors associated DED.A total 42 consented complete investigation (response rate 46.15%). There 26 (61.90%) who diagnosed by OSDI,...
Based on $(10087 \pm 44)\times10^6$ $J/\psi$ events collected with the BESIII detector at BEPCII, double Dalitz decay $\eta'\to e^+e^-e^+e^-$ is observed for first time via $J/\psi\to\gamma\eta'$ process. The significance found to be 5.7$\sigma$ systematic uncertainties taken into consideration. Its branching fraction determined $\mathcal{B}(\eta'\to e^+ e^- e^-) =(4.5\pm1.0(\mathrm{stat.})\pm0.5(\mathrm{sys.})) \times 10^{-6}$.
A bstract Using a data sample corresponding to an integrated luminosity of 11.3 fb − 1 collected at center-of-mass energies from 4.23 4.70 GeV with the BESIII detector, we observe process e + → π 0 ψ 2 (3823) for first time statistical significance 6 . standard deviations. The ratio average cross sections and is determined be $$ \mathcal{R}=\frac{\sigma \left[{e}^{+}{e}^{-}\to {\pi}^0{\pi}^0{\psi}_2(3823)\right]}{\sigma {\pi}^{+}{\pi}^{-}{\psi}_2(3823)\right]}=0.57\pm 0.14\pm 0.05 <mml:math...