A5068917118- Chromatography in Natural Products
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Food Quality and Safety Studies
- Ionic liquids properties and applications
- Analytical Chemistry and Chromatography
- Phytochemistry and biological activity of medicinal plants
- Tea Polyphenols and Effects
- Mesoporous Materials and Catalysis
- Bioactive natural compounds
- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- Electrochemical Analysis and Applications
- Analytical chemistry methods development
- Bacteriophages and microbial interactions
- Medicinal Plant Pharmacodynamics Research
- Per- and polyfluoroalkyl substances research
- Botanical Research and Chemistry
- Chemical and Physical Properties in Aqueous Solutions
- interferon and immune responses
- Food composition and properties
- Protein Hydrolysis and Bioactive Peptides
- Saffron Plant Research Studies
- Bacterial biofilms and quorum sensing
Beijing Technology and Business University
2016-2025
Beijing University of Chemical Technology
2020-2025
Zhejiang University
2014-2022
China University of Geosciences
2019-2020
Beijing Institute of Technology
1998-2019
FORCE Technology (Norway)
2019
Hangzhou Xixi hospital
2017
RIKEN Advanced Science Institute
2015
Kunming University
2012
Beijing Wuzi University
2012
A fundamental strategy of eukaryotic antiviral immunity involves the cGAS enzyme, which synthesizes 2′,3′-cGAMP and activates effector STING. Diverse bacteria contain cGAS-like enzymes that produce cyclic oligonucleotides induce anti-phage activity, known as CBASS. However, this activity has only been demonstrated through heterologous expression. Whether harboring CBASS antagonize co-evolve with phages is unknown. Here, we identified an endogenous enzyme in Pseudomonas aeruginosa generates...
Abstract The aim of this work is to shed light on the origins unique properties by studying relationship between viscosity and hydrogen‐bonding interactions terpene‐based natural deep eutectic solvents (NADES). Five systems including camphor/formic acid, menthol/acetic menthol/β‐citronellol, menthol/lactic thymol/β‐citronellol are prepared (molar ratio 1:1). Their structures nature associated hydrogen bonds investigated through multiple methods theories. NADES consistent with product...
In-situ ionic liquid-dispersive liquid-liquid microextraction (IL-DLLME) method was developed as a pretreatment for the detection of six chlorophenols (CPs) in honey samples. The hydrophobic liquid [C4MIM][NTf2], formed in-situ by hydrophilic [C4MIM][BF4] and ion exchange reagent LiNTf2 used microextractant solvent CPs from sample. Then enriched analytes were back-extracted into 40 μL 0.14 M NaOH solution finally subjected to analysis high-performance chromatography. showed low limit CPs,...
It has been shown that whole grains and dietary fiber are important for their fermentation characteristics in the large intestine, drawing more attention to quinoa polysaccharides. In this study, we evaluated prebiotic effect of seeds polysaccharides after human simulated digestion. The modulatory (QPs) on gut microbiota was by vitro using fecal microbiota. yield extraction 15.45%. digestibility cooked uncooked simulation digestion 69.04% 64.09%, respectively. composition metabolic products...
Gynura divaricata (L.) DC is a long-used medicinal and edible plant in China folk. Its hyperglycemic effects have garnered increasing public attention recent years. This study revealed that the ethyl acetate (EtOAc) butanol (BuOH) partition fractions of G. crude extract exhibited significantly higher α-glucosidase inhibition activity enhanced glucose uptake ability compared to other fractions. Guided by hypoglycemic bioassay, these two were subjected isolation active compounds using...
Jumbo bacteriophages of the ϕKZ-like family assemble a lipid-based early phage infection (EPI) vesicle and proteinaceous nucleus-like structure during infection. These structures protect from nucleases may create selective pressure for immunity mechanisms targeting this specific family. Here, we identify "jumbo killer" (Juk), two-component immune system that terminates phages, suppressing expression genes preventing DNA replication nucleus assembly while saving cell. JukA (formerly YaaW)...
The viscosity of natural deep eutectic solvent (NADES) plays an important role in determining how they are used industrially. However, most NADES systems exhibit a relatively high viscosity. Terpene-based mixtures have attracted widespread interest as low-viscosity solvents. goal this work was to shed light on the nature their unique properties by exploring relationship between and non-covalent interactions. microstructure characteristics different were investigated through multiple methods...