A5057329591- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Retinal Development and Disorders
- Ocular Surface and Contact Lens
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Ocular and Laser Science Research
- Retinal and Macular Surgery
- Ocular Disorders and Treatments
- Laser Applications in Dentistry and Medicine
- Medical and Biological Sciences
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- Facial Trauma and Fracture Management
- Mesenchymal stem cell research
- Ophthalmology and Eye Disorders
- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Retinoids in leukemia and cellular processes
- Drug-Induced Ocular Toxicity
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- melanin and skin pigmentation
Intersectoral Research and Technology Complex Eye Microsurgery
2015-2024
Ministry of Health of the Russian Federation
2015-2024
Moscow State University of Medicine and Dentistry
2015-2024
Scientific Center of Children's Health
2021
Introduction. Idiopathic epiretinal membrane is a formation of fibrous cellular tissue in the macula. To our understanding there no data on interaction structures with each other, as well relationship them inner limiting membrane. The morphology latter during idiopathic has been scarcely studied due to absence specific immunohistochemical markers. We focused localizing and exploring components determining markers that allow identification membranes samples. Materials methods. analyzed 29...
Lipofuscin granules from retinal pigment epithelium (RPE) cells contain bisretinoid fluorophores, which are photosensitizers and phototoxic to cells. In the presence of oxygen, bisretinoids oxidized form various products, containing aldehydes ketones, also potentially cytotoxic. a prior study, we identified that oxidation degradation products have both hydrophilic amphiphilic properties, allowing their diffusion through lipofuscin granule membrane into RPE cell cytoplasm, thiobarbituric acid...
Purpose: To assess the anatomic and visual results of modified glueless simple limbal epithelial transplantation (G-SLET) in treatment unilateral stem cell deficiency (LSCD). Methods: This is a retrospective analysis 2 patients who received G-SLET for corneal reepithelization after eye burn. After recipient bed preparation on with LSCD, radial symmetrical superficial incisions were applied to periphery. Next, short (1 mm) slightly oblique or horizontal tunnels formed every incision. The...
Original article Experimental study of manual and femtosecond laser-assisted methods for cutting limbal mini-transplants B.E. Malyugin, S.A. Borzenok, O.N. Nefedova, D.S. Ostrovskii, M.Yu. Gerasymov, A.V. Shatskikh S. Fyodorov Eye Microsurger y Federal State Institution, Moscow, Russian Federation A. Yevdokimov Moscow University Medicine Dentistr y, Purpose. To define optimal parameters laser (FSL) (Femto LDV Z8, Ziemer, Switzerland) to be further used stem cells (LSC) transplantation...
Adenoviruses cause a wide variety of human infectious diseases. Adenoviral conjunctivitis and epidemic keratoconjunctivitis are commonly associated with species D adenoviruses. Currently, there is no sufficient or appropriate treatment to counteract these adenovirus infections. Thus, an urgent need for new etiology-directed therapies selective activity against To address this problem, the adenoviral early genes E1A E2B (viral DNA polymerase) seem be promising targets. Here, we propose...
Aim . To investigate cell reaction to different materials, potentially suitable for intracorneal lens (ICL) production. Materials and methods A plane surface (2D) corneal stromal culture was performed in the presence of experimental polymer samples, such as hydroxyethylmethacrylate, oligourethanemethacrylate polymethylmethacrylate. The dynamics numbers evaluated over time. Conclusion on biocompatibility made based obtained data. Results. In each groups there a trend toward steady increase...
The review presents an analysis of clinical trials results for autologous cultured oral mucosal epithelium transplantation (COMET) in patients with bilateral corneal limbal stem cell deficiency (LSCD) over the past 15 years. Detailed characteristics and evaluation are given anatomical outcomes, visual acuity changes, complication rates. obtained during confirm consistency concept re-epithelization by means COMET. COMET promoted persistent 81.5% cases, improvement 78.8% LSCD. does not require...
Our understanding of the role adipose tissue has been completely changed during past decades. The knowledge its contribution to endocrine and immune pathways opened new insights on pathogenesis therapy many diseases perspectives for regenerative medicine. further researches should be provided study anatomy functions local fat depots in more details. Of most interest is orbital due origin from neural crest. This review represents current data about anatomy, structure, cell composition...
Human posterior corneal epithelium (corneal endothelium) has limited proliferative activity both in vivo and vitro. Disease or dysfunction these cells leads to impaired transparency of varying degrees severity, up blindness. Currently, the only effective standard treatment for endothelial is transplantation donor cornea that contains a pool healthy functionally active cells. However, there global shortage corneas, which led an unmet clinical need fact 1 patient out 10 receives surgical...
This article presents the results of studying impact recombinant spidroin hydrogel on posterior epithelial cells and human corneal keratocytes in an vitro experiment. The World Health Organization its studies has established a high prevalence injuries among population developing countries. In recent years, various technologies have been proposed to restore damaged surface cornea. use biodegradable silk-based materials, such as spidroins is one main parts scientific research regeneration....