A5066069508- Fish Ecology and Management Studies
- Reproductive biology and impacts on aquatic species
- Cancer-related molecular mechanisms research
- Fish Biology and Ecology Studies
- Genomics and Phylogenetic Studies
- Aquaculture Nutrition and Growth
- Reproductive Biology and Fertility
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sperm and Testicular Function
- Genetic diversity and population structure
- Circular RNAs in diseases
- Aquaculture disease management and microbiota
- MicroRNA in disease regulation
- Physiological and biochemical adaptations
- Insect Resistance and Genetics
- RNA Research and Splicing
- Renal and related cancers
- Psoriasis: Treatment and Pathogenesis
- Epigenetics and DNA Methylation
- Helminth infection and control
- Bird parasitology and diseases
- Vector-borne infectious diseases
- Microbial Community Ecology and Physiology
- Identification and Quantification in Food
- Animal Genetics and Reproduction
China University of Geosciences (Beijing)
2024-2025
Fujian Institute of Oceanography
2024-2025
Ministry of Natural Resources
2024-2025
Sichuan Agricultural University
2014-2024
University of Michigan–Ann Arbor
2009-2024
Xinjiang Agricultural University
2024
Zhongda Hospital Southeast University
2024
Chinese Research Academy of Environmental Sciences
2023
Southwest University of Science and Technology
2023
Affiliated Hospital of Guizhou Medical University
2022-2023
Common variants in the transcription factor 7-like 2 (TCF7L2) gene have been identified as strongest genetic risk factors for type diabetes (T2D). However, mechanisms by which these non-coding increase T2D are not well-established. We used 13 expression assays to survey mRNA of multiple TCF7L2 splicing forms up 380 samples from eight types human tissue (pancreas, pancreatic islets, colon, liver, monocytes, skeletal muscle, subcutaneous adipose and lymphoblastoid cell lines) observed a...
Maintaining osmotic equilibrium plays an important role in the survival of cold-water fishes. Heat stress has been proven to reduce activity Na+/K+-ATPase gill tissue, leading destruction equilibrium. However, mechanism megatemperature affecting osmoregulation not fully elucidated.In this study, Siberian sturgeon (Acipenser baerii) was used analyze histopathological change, plasma ion level, and transcriptome tissue subjected 20℃, 24℃and 28℃. The results showed that ROS level damage were...
Introduction The utilization of large-scale claims databases has greatly improved the management, accessibility, and integration extensive medical data. However, its potential for systematically identifying comorbidities in context skin diseases remains unexplored. Methods This study aims to assess capability a comprehensive database linked 14 specific skin-related conditions examining temporal changes their association patterns. employed retrospective case-control cohort design utilizing 13...
BV is a significant concern in women's health with varying prevalence rate different cities of China. The condition has been linked to the acquisition STIs, including HIV and HPV, can lead infertility, adverse obstetric outcomes. We conducted comprehensive literature search PubMed. was performed from 01/01/2018 01/09/2023. following terms were used: bacterial vaginosis cytokine. also manually searched reference lists included studies relevant reviews identify additional articles. presence...
Two Gram-stain-negative, motile, non-spore-forming, aerobic or facultative anaerobic and short rod-shaped bacterial strains, 25B02-3
The poles of the Earth harbour many novel micro-organisms that have not yet been isolated and identified. Here, a Gram-stain-negative, motile, aerobic rod-shaped bacterial strain, designated as wDCs-4 T , was from surface seawater collected Weddell Sea in Antarctica. It grows at 4–40 °C (optimum 10–15 °C), pH 4–8 7) presence 0–4% NaCl (w/v, optimum 0.5–1%). complete 16S rRNA gene strain had maximum sequence identity with Oceanobacter mangrovi SM2-42 (97.2%), followed by Thalassolituus...
Epigenetic variants carried by circulating tumor DNA can be used as biomarkers for early detection of hepatocellular carcinoma (HCC) noninvasive liquid biopsy. However, traditional methylation analysis method, bisulfite sequencing, with disadvantages severe damage, is limited in application low-amount cfDNA analysis.Through mild enzyme-mediated conversion, enzymatic methyl sequencing (EM-seq) ideal precise determination cell-free and provides an opportunity HCC detection. EM-seq control...
Cyp19a1a is a key enzyme in the pathway that converts androgens into estrogen and regulated by TGF-β signaling. Smad4 FoxH1 are downstream effectors of signaling may play important roles ovarian development M. albus. We investigated expression pattern using qRT‒PCR immunofluorescence, then tested changes smad4 foxh1 after ovary incubation with FSH vitro, analysed regulation cyp19a1a transcription dual-luciferase reporter assays. found encoded putative protein 449 amino acids harbored three...
Vanadate, which mimics the biological effects of insulin, also inhibits lipolysis in rat adipocytes. Here we demonstrate that antilipolytic effect vanadate differs from insulin at least by five following criteria: 1) mediated high (supraphysiological) concentrations catecholamines; 2) antagonizes (Bu)2cAMP-mediated lipolysis; 3) isobutylmethylxanthine-dependent lipolysis, 4) okadaic acid; and 5) wortmannin, blocks fails to block vanadate-mediated antilipolysis. Vanadate does activate...
Luteinizing hormone (Lh) and follicle-stimulating (Fsh) control many aspects of gonadal development function in teleosts. In the present paper, specific antisera against ricefield eel Lhb (Lh beta subunit), Fshb (Fsh Cga (the common pituitary glycoprotein alpha subunit) were generated, cellular localization, initial appearance, subsequent gonadotrophs relation to early ovarian differentiation eel, a protogynous sex-changing teleost, examined with immunochemistry. Lhb- Fshb-immunoreactive...
Understanding the genetic structure and differentiation in endangered species is of significance detecting their phylogenetic relationships prioritizing conservation. Here we sampled five Cycas endemic to southwest China genotyped among them using genotyping-by-sequencing (GBS) method. C. hongheensis showed high diversity, but other four low diversity. The diversity between wild cultivated populations was similar for debaoensis guizhouensis, respectively. Low gene flow were found debaoensis,...
Abstract Background Schizothorax o’connori is an endemic fish distributed in the upper and lower reaches of Yarlung Zangbo River China. It has experienced a fourth round whole gene replication events good model for exploring genetic differentiation environmental adaptability Qinghai-Tibet Plateau. The uplift Plateau led to changes river system, thereby affecting exchange population between populations. With release genome data, resequencing been widely used evolutionary analysis screening...
Fish behavior measurements are important for river and fishery scientists to protect fish resources ecological engineers guide ecosystem conservation but they can pose a practical challenge. In this study, an acoustic camera was used observe the migration patterns of species downstream under-construction hydroelectric dam, Lianghekou dam in middle Yalong River, China. The fixed-point method employed continuously measure using dual-frequency identification sonar (DIDSON) during spawning...