Yifan Hu

ORCID: 0009-0006-4951-985X
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Research Areas
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • MicroRNA in disease regulation
  • Physiological and biochemical adaptations
  • Cancer, Hypoxia, and Metabolism
  • Nanoparticles: synthesis and applications
  • Frailty in Older Adults
  • Autophagy in Disease and Therapy
  • Nutrition and Health in Aging
  • Ovarian function and disorders
  • Nutritional Studies and Diet
  • Barrier Structure and Function Studies
  • Endoplasmic Reticulum Stress and Disease
  • Surface Modification and Superhydrophobicity
  • Venous Thromboembolism Diagnosis and Management
  • High Altitude and Hypoxia
  • Diet, Metabolism, and Disease
  • Lung Cancer Diagnosis and Treatment
  • Cardiovascular Disease and Adiposity
  • Esophageal Cancer Research and Treatment
  • Stress Responses and Cortisol
  • 3D Printing in Biomedical Research
  • Reproductive Biology and Fertility
  • Peroxisome Proliferator-Activated Receptors
  • Sleep and related disorders

Yunnan Academy of Agricultural Sciences
2025

Nantong University
2025

Affiliated Hospital of Nantong University
2025

Sichuan Agricultural University
2022-2024

University of Jinan
2024

Center for Life Sciences
2024

Chengdu University of Traditional Chinese Medicine
2024

China Agricultural University
2024

Zhejiang University
2023

Beijing University of Chinese Medicine
2023

Background Research based on observation has demonstrated a relationship between sleep traits and frailty; however, it remains uncertain if this correlation indicates causation. The purpose of study was to look at the causal that exists frailty traits. Method Using summaries from genome-wide association self-reported features index, we performed bidirectional Mendelian randomization (MR) analysis. Examining relationships seven sleep-related goal. major method used calculate effect estimates...

10.3389/fpubh.2024.1381482 article EN cc-by Frontiers in Public Health 2024-05-09

Abstract Untreated osteochondral defects will develop into osteoarthritis, affecting patients’ quality of life. Since articular cartilage and subchondral bone exhibit distinct biological characteristics, repairing remains a major challenge. Previous studies have tried to fabricate multilayer scaffolds with traditional methods or 3D printing technology. However, the efficacy is unsatisfactory because poor control over internal structures lack integrity between adjacent layers, severely...

10.1088/1758-5090/ad0071 article EN cc-by Biofabrication 2023-10-05

Abstract Background Adequate level of carbohydrates in aquafeeds help to conserve protein and reduce cost. However, studies have indicated that high-carbohydrate (HC) diet disrupt the homeostasis gut–liver axis largemouth bass, resulting decreased intestinal acetate butyrate level. Method Herein, we had concepted a set feeding experiment assess effects dietary sodium (SA) (SB) on liver health microbiota bass fed an HC diet. The experimental design comprised 5 isonitrogenous isolipidic diets,...

10.1186/s40104-024-01009-4 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2024-04-03

To investigate the effects of lemongrass essential oil on key volatile aroma compounds pickled radish (PR) during storage, this study used headspace–gas chromatography–ion mobility spectrometry, fingerprint analysis, multivariate statistical and molecular docking to different PR samples. The results indicated that a total 48 aromatic were identified. Fingerprint analysis revealed profiles samples at storage stages different. Using screening criteria p < 0.05 variable importance for...

10.3390/foods14050727 article EN cc-by Foods 2025-02-21

Radiomics research in esophageal cancer (EC) has made considerable advancements. However, manual segmentation, which is relied upon clinical and scientific workflows, remains time-consuming inconsistent. This study aimed to develop validate a deep learning (DL) model for the automatic detection segmentation of EC lesions contrast-enhanced computed tomography (CT) images. We retrospectively collected CT data patients with confirmed by pathology from January 2017 September 2021 at three...

10.21037/qims-24-1116 article EN Quantitative Imaging in Medicine and Surgery 2025-03-01

In this study, six diets with different concentrations of nano-iron (0, 30, 60, 120, 240, 480 mg/kg) were designed to evaluate the growth, hematological parameters, antioxidant and immune status, hypoxia tolerance juvenile Largemouth Bass (initial weight 6.2 ± 0.2 g) through a 10-week feeding trial. The results showed that addition 60 mg/kg significantly improved growth performance (weight gain, WG; specific rate, SGR), parameters (red blood cell counts, RBC; hemoglobin, Hb; haematocrit,...

10.1016/j.aqrep.2023.101759 article EN cc-by-nc-nd Aquaculture Reports 2023-09-30

In this study, we explored the effects of 4 weeks intermittent hypoxic exposure (IHE) on liver angiogenesis and related regulatory mechanisms in largemouth bass (Micropterus salmoides). The results indicated that O2 tension for loss equilibrium (LOE) decreased from 1.17 to 0.66 mg/L after IHE. Meanwhile, red blood cell (RBC) hemoglobin concentrations significantly increased during Our investigation also found observed increase was correlated with a high expression regulators, such as Jagged,...

10.1021/acs.est.2c07329 article EN Environmental Science & Technology 2023-02-21

Non-alcoholic fatty liver disease(NAFLD) is common worldwide and has previously been reported to be associated with sleep traits. However, it not clear whether NAFLD changes traits or the in lead onset of NAFLD. The purpose this study was investigate causal relationship between using Mendelian randomization. We proposed a bidirectional randomization (MR) analysis performed validation analyses dissect association Genetic instruments were used as proxies for sleep. Data genome-wide study(GWAS)...

10.3389/fendo.2023.1159258 article EN cc-by Frontiers in Endocrinology 2023-06-02

Well-tailored construction of icephobic surfaces with mechanical robustness and investigation the structure-property relationships at molecular level are highly desirable. Herein, a series norbornene-based fluorinated polyolefin copolymers (FPOR-

10.1021/acs.langmuir.4c01329 article EN Langmuir 2024-05-23

The mechanisms behind the selection and initial recruitment of primordial follicles (PmFs) from non-growing PmF pool during each estrous cycle in females remain largely unknown.This study demonstrates that PmFs closest to ovulatory follicle are preferentially activated mouse ovaries under physiological conditions.PmFs located within 40 μm were more likely be compared those situated further away peri-ovulation period.Repeated superovulation treatments accelerated depletion reserve, whereas...

10.7150/ijbs.95020 article EN cc-by-nc International Journal of Biological Sciences 2024-01-01

Yinchenhao decoction (YCHD) is a famous traditional Chinese medicine for improving hepatic metabolism disorder. The aim of this study was to investigate the effects YCHD on lipid juvenile largemouth bass fed high-carbohydrate diet. Triplicate groups fish (5.6 ± 0.2 g) were six experimental diets (one low-carbohydrate diet and five with gradients YCHD) 10 weeks. results showed that appropriate administration reversed adverse growth performance. Meanwhile, decreased depositions T-CHO, TG NEFA,...

10.1111/are.16119 article EN Aquaculture Research 2022-09-18

Epicardial adipose tissue (EAT) is a key aspect in the investigation of cardiac pathophysiology. We sought to develop deep learning (DL) model for fully automatic extraction and quantification EAT through pulmonary computed tomography venography (PCTV) images.In this retrospective study, we included 128 patients with atrial fibrillation PCTV from 2 hospitals. A DL automated segmentation was developed training set 51 validation 13 hospital A. The algorithm further validated using an internal...

10.21037/qims-23-233 article EN Quantitative Imaging in Medicine and Surgery 2023-09-25

<title>Abstract</title> Nano-additives can improve the absorption and utilization of feed nutrients. In this study, we reported effects supplementary nano iron (0, 30, 60, 120, 240 480 mg/kg) on intestinal tract function largemouth bass juveniles. Firstly, 60 mg/kg improved specific growth rate, significantly increased height width villi area, physical barrier juvenile bass. Secondly, supplementation low concentration increase activity antioxidant enzymes (CAT T-SOD), enhance expression...

10.21203/rs.3.rs-4676994/v1 preprint EN cc-by Research Square (Research Square) 2024-08-01

Abstract As a major source of energy, carbohydrates have protein sparing effect. However, excessive consumption can harm the intestinal barriers fish, particularly carnivorous fish. The traditional Chinese medicine component, Yinchenhao Decoction (YD), may improve and microbial community equilibrium in both animals humans. In current investigation, series NC HC with graded YD experiments were undertaken, results suggest that 2% 4% treatments significantly reduced gut inflammation mucosal...

10.21203/rs.3.rs-3247039/v1 preprint EN cc-by Research Square (Research Square) 2023-08-17

Background: Observational studies have reported that individuals diagnosed with polycystic ovary syndrome (PCOS) face a heightened vulnerability to developing post-traumatic stress disorder (PTSD). However, it is unclear whether this relationship causal. Consequently, we implemented bidirectional Mendelian randomization (MR) analysis examine the empirical causal association of PCOS and PTSD. Methods: We acquired genetic data for through comprehensive meta-analysis from several large-scale...

10.31083/j.ceog5009193 article EN cc-by Clinical and Experimental Obstetrics & Gynecology 2023-09-20

Abstract Background Adequate levels of carbohydrates in aquafeeds help conserve protein and reduce costs. However, studies have shown that a high-carbohydrate (HC) diet disrupts the homeostasis gut–liver axis largemouth bass, resulting decreased intestinal acetate butyrate levels. Herein, we assessed effects sodium (SA) (SB) on liver health microbiota bass fed an HC diet. The experimental design comprised five isonitrogenous isolipid diets, including LC (9% starch), (18% HCSA starch; 2 g/kg...

10.21203/rs.3.rs-3657807/v1 preprint EN cc-by Research Square (Research Square) 2023-12-04
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