This study aimed to investigate differences in testicular tissue morphology, gene expression, and marker genes between sexually immature (1-year-old) mature (10-year-old) Mongolian horses. The purposes of our research were provide insights into the reproductive physiology male horses identify potential markers for sexual maturity. methods we applied included transcriptomic profiling cells using single-cell sequencing techniques. Our results revealed significant morphology expression patterns...

Biologists and scientists can use the data from Alzheimer's disease (AD) gene expression microarrays to mine AD disease-related genes. Because of disadvantages such as small sample sizes, high dimensionality, a level noise, it is difficult obtain accurate meaningful biological information profiles. In this paper, we present novel approach for utilizing microarray identify morbigenous The Fisher score, classical feature selection method, utilized evaluate importance each gene. Genes with...

Abstract. Cryopreservation of semen has advanced significantly with the development artificial insemination techniques, but post-thawed sperm often exhibit reduced viability, membrane integrity, and acrosome integrity compared to fresh sperm, leading decreased fertilization capacity. Oxidative stress is a major concern during cryopreservation. This study investigated use resveratrol (RSV), potent antioxidant, in cryopreservation Mongolian horse semen. Different concentrations RSV were...

Colitis in equines has high morbidity and mortality rates, which severely affects the development of equine-breeding industry. With issuance antibiotic bans, there is an urgent need for healthier more effective alternatives. In recent years, probiotics have been widely used as microbial feed additives animal husbandry, playing a crucial role preventing treating diarrhea regulating host immune function. this study, we isolated screened strain with rapid stable acid production using...

Abstract Prostate specific membrane antigen (PSMA) is overexpressed on prostate tumor cells and the neovascular endothelia various solid tumors. A bivalent immunotoxin generated by fusing a fold‐back single‐chain diabody derived from Fv fragments of an anti‐PSMA monoclonal antibody with truncated diphtheria toxin (DT) containing activity translocation domains [A‐dmDT390‐scfbDb(PSMA)] might be suitable for targeted therapy tumors that overexpress PSMA. In this study, PSMA‐positive...

Testicular development and spermatogenesis are tightly regulated by both coding non-coding genes, with mRNA lncRNA playing crucial roles in post-transcriptional gene expression regulation. However, there significant differences regulatory mechanisms before after sexual maturity. Nevertheless, the mRNAs lncRNAs testes of Mongolian horses have not been systematically identified. In this study, we first identified testicular tissues sexually immature mature at tissue protein levels,...

During follicular development, changes in the composition of fluid are synchronized with development oocytes. Our aim was to screen key factors affecting oocyte maturation and optimize vitro culture protocol by understanding proteins metabolites fluid. Follicles divided into three groups according their diameter (small follicle (SFF): 10 mm < d 20 mm; medium (MFF): 30 large (LFF): d). Proteins from were analyzed mass spectrometry. The results showed that: LFF vs MFF, differential abundant...

Fermented mare's milk (koumiss), a traditional Central Asian dairy product derived from fermented milk, is renowned for its unique sour taste and texture. It has long been consumed by nomadic tribes nutritional medicinal benefits. This study aimed to comprehensively analyze the protective effects of koumiss against alcohol-induced harm across behavioral, hematological, gastrointestinal, hepatic, reproductive dimensions using mouse model. Optimal intoxicating doses alcohol were determined,...

We isolated and characterized microsatellite loci for the redcrowned crane (Grus japonensis) from a microsatellite-enriched database, which was obtained using high-throughput sequencing technology.We designed primer sets 445 after initial screening, 34 were genotyped in 31 red-crowned cranes.The number of observed alleles ranged 3 to 10. Observed expected heterozygosities 0.197 0.935 0.453 0.887, respectively; mean polymorphic information content 0.663.Loci Lia10943, Lia60455, Lia48514,...

Interspecific hybridization often shows negative effects on hybrids. However, only a few multicellular species, limited to handful of plants and animals, have shown partial genetic mechanisms by which leads low fitness in Here, explore the outcome combining two genomes horse donkey, we analyzed whole-genome sequences from an Equus parent-offspring trio using Illumina platforms. We generated 41.39× 46.21× coverage for mule, respectively. For 40.38× sequence was stored our laboratory....

The 128-EEA1 and the 128-EIA1 algorithms have been widely applied to security of 4G mobile communication network, which are also upcoming 5G network. However, performance nowadays still doesn't satisfy requirement high throughput application on In this article, we proposed a novel 22-in-1 architecture, is based SNOW3G algorithm, it supports both 128-EIA1. We firstly design an f8_f9 single module, implemented by Altera Stratix V series FPGA. Under synthesization Quartus II 13.0, algorithm...

OBJECTIVE To explore the prognostic risk factors of bloodstream infection (BSI) in intensive care unit (ICU) patients, furthermore, to provide a reliable evidence for early warning and treatment critical patients with BSI. METHODS A retrospective study was performed. The clinical data blood culture-positive admitted ICU Affiliated Hospital Guizhou Medical University from January 1 September 30, 2019 were analyzed. including gender, age, proportion basic diseases, acute physiology chronic...

Lipid droplets (LDs) are important multifunctional organelles responsible for lipid metabolism of postmortem muscle. However, the dynamics in their building blocks (cores and layers) phosphorylation droplet-related proteins (LDRPs) regulating meat lipolysis remain unknown at salt-stimulated conditions.LDRPs extracted from cured porcine biceps femoris (1% 3% salt) were subjected to label-free quantitative phosphoproteomic analysis LDs morphological validation. Results indicated that salt...

Aiming at the inefficiency under parallel environment or large data computation, HAIFA hash function based on Lorenz chaos is constructed in parallel, and a proposed. The algorithm compresses each message block independently can be executed concurrently. After value of obtained, every two values are combined. odd-numbered rounds combined with modular addition right loop operation, while even-numbered XOR left operation. difference round operation further enhances anti-collision anti-forgery...

In this study, a cellular automaton model for the oxidation of binary alloys is proposed, by treating internal and external separately simultaneously.As an example, nickel-chromium with formation spinel doping effect simulated.The rate micro-morphology simulation are compared experimental results others to verify reliability model.The influences alloy content, reaction temperature interdiffusion velocity on forecast.Furthermore, capable simulate in oxidants other than oxygen.

In this study, oxidation and sulfuration of water wall materials are simulated by cellular automata. The automata model for pure metals binary alloys is proposed. By treating internal external separately simultaneously, the iron iron-chromium simulated. comparing rate micro-morphology simulation with previous experimental results, reliability verified. using model, dependence rates on reaction temperature, alloy content, interdiffusion velocity forecast. results indicate that obviously lower...

High-Dimensional and Incomplete matrices, which usually contain a large amount of valuable latent information, can be well represented by Latent Factor Analysis model. The performance an LFA model heavily rely on its optimization process. Thereby, some prior studies employ the Particle Swarm Optimization to enhance model's However, particles within swarm follow static evolution paths only share global best limits particles' searching area cause sub-optimum issue. To address this issue, paper...

Digging out the latent information from large-scale incomplete matrices is a key issue with challenges. The Latent Factor Analysis (LFA) model has been investigated in depth to an alyze information. Recently, Swarm Intelligence-related LFA models have proposed and adopted widely improve optimization process of high efficiency, i.e., Particle Optimization (PSO)-LFA model. However, hyper-parameters PSO-LFA tune manually, which inconvenient for adoption limits learning rate as fixed value. To...

In recent years, along with the rapid development of big data and AI technologies, knowledge graphs have also experienced significant growth. The vectorized representation entities relations in has proven beneficial for various graph-related applications. However, traditional graph embedding methods are designed centralized graphs, which cannot effectively represent distributed real-world while ensuring security. this paper, we improve aggregation method federated propose a Federated model...

High-Dimensional and Incomplete (HDI) matrices, which usually contain a large amount of valuable latent information, can be well represented by Latent Factor Analysis (LFA) model. The performance an LFA model heavily rely on its optimization process. Thereby, some prior studies employ the Particle Swarm Optimization (PSO) to enhance model's However, particles within swarm follow static evolution paths only share global best limits particles' searching area cause sub-optimum issue. To address...

High-Dimensional and Incomplete (HDI) matrices, which usually contain a large amount of valuable latent information, can be well represented by Latent Factor Analysis (LFA) model. The performance an LFA model heavily rely on its optimization process. Thereby, some prior studies employ the Particle Swarm Optimization (PSO) to enhance model's However, particles within swarm follow static evolution paths only share global best limits particles' searching area cause sub-optimum issue. To address...