A5011944902- Cold Atom Physics and Bose-Einstein Condensates
- Atomic and Subatomic Physics Research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Quantum, superfluid, helium dynamics
- Cancer-related molecular mechanisms research
- Artificial Intelligence in Healthcare
- Traditional Chinese Medicine Studies
- Quantum many-body systems
- Bone Metabolism and Diseases
- Autophagy in Disease and Therapy
- Physics of Superconductivity and Magnetism
- Reproductive Physiology in Livestock
- Body Composition Measurement Techniques
- Advanced Technologies in Various Fields
- Muscle metabolism and nutrition
- Muscle Physiology and Disorders
- Toxoplasma gondii Research Studies
- High Altitude and Hypoxia
- Cardiovascular Health and Risk Factors
- Cancer Treatment and Pharmacology
- GDF15 and Related Biomarkers
- Silk-based biomaterials and applications
- Quantum and electron transport phenomena
- Spinal Cord Injury Research
Inner Mongolia Agricultural University
2024-2025
University of Science and Technology of China
2022-2025
Hefei National Center for Physical Sciences at Nanoscale
2022-2025
Nanjing University of Chinese Medicine
2013-2024
Changshu No.1 People's Hospital
2010-2022
Nanjing University
2011-2013
Soochow University
2011
Ultracold atoms in optical lattices form a competitive candidate for quantum computation owing to the excellent coherence properties, highly parallel operations over spins, and ultralow entropy achieved qubit arrays. For this, massive number of entangled atom pairs have been realized superlattices. However, more formidable challenge is scale up detect multipartite entanglement, basic resource computation, due lack manipulations local atomic spins retroreflected bichromatic In this Letter, we...
Abstract Stimulating bone formation potentially suggests therapeutics for orthopedic diseases including osteoporosis and osteoarthritis. Osteoblasts are key to remodeling because they act as the only bone-forming cells. miR-877-5p has a chondrocyte-improving function in osteoarthritis, but its effect on osteoblast differentiation is unknown. Here, miR-877-5p-mediated was studied. Real-time reverse transcriptase-polymerase chain reaction performed measure expression during osteogenic of...
Introduction: Equine chorionic girdle cells can give rise to the endometrial cup, a structure that secretes equine gonadotropin (eCG). To date, mechanisms underlying proliferation, differentiation, invasion, and hormone secretion of are not fully understood. During human pregnancy, interleukin-6 (IL-6) is maternally expressed stimulate invasion migration syncytiotrophoblast influence synthesis gonadotropin. Although many previous studies reported same upregulation IL-6 during placentation,...
Hydrogen peroxide (H2O2) induces oxidative injury to human osteoblasts. The expression and potential function of circular RNA HIPK3 (circHIPK3) in H2O2-treated osteoblasts were tested. We show that H2O2 significantly downregulated circHIPK3 OB-6 cells primary Furthermore, levels decreased the necrotic femoral head tissues dexamethasone-treated patients. In osteoblastic osteoblasts, forced overexpression by a lentiviral construct alleviated H2O2-induced viability reduction, cell death...
Previous research has shown that leucine (Leu) can stimulate and enhance the proliferation of equine skeletal muscle satellite cells (SCs). The gene expression profile associated with Leu-induced SCs also been documented. However, specific role Leu in regulating slow-twitch fibers (slow-MyHC) mitochondrial function SCs, as well underlying mechanism, remains unclear. During this investigation, underwent culturing differentiation medium were subjected to varying concentrations (0 mM, 0.5 1 2 5...
Osteogenesis is the key process of bone homeostasis differentiation. Numerous studies have manifested that circular RNA (circRNA) a critical regulator osteogenesis. The research was to explore circRNA-mediated mechanisms in osteogenesis.Bone marrow mesenchymal stem cells (BMSCs) were cultured and induced osteogenic differentiation (OD). Then, oe-circ-FKBP5, oe-NC, si-circ-FKBP5, si-NC, miR-205-5p mimic, mimic NC, inhibitor, inhibitor sh-RUNX2, or sh-NC transfected into BMSCs. Alkaline...
We report on an experimental simulation of the spin-1 Heisenberg model with composite bosons in a one-dimensional chain based two-component Bose-Hubbard model. Exploiting our site- and spin-resolved quantum gas microscope, we observed faster superexchange dynamics system compared to its spin-1/2 counterpart, which is attributed enhancement effect multi-bosons. further probed nonequilibrium spin driven by single-ion anisotropy terms, unveiling linear expansion spin-spin correlations, limited...
During follicular development, changes in the composition of fluid are synchronized with development oocytes. Our aim was to screen key factors affecting oocyte maturation and optimize vitro culture protocol by understanding proteins metabolites fluid. Follicles divided into three groups according their diameter (small follicle (SFF): 10 mm < d 20 mm; medium (MFF): 30 large (LFF): d). Proteins from were analyzed mass spectrometry. The results showed that: LFF vs MFF, differential abundant...
Osteoporosis is defined as a bone condition characterized by mass reduction, micro-architectural and quality deterioration, leading to compromised strength increased chances of fracture. Evidence have shown an essential role microRNAs (miRNAs) in various osteogenic differentiation processes. However, the function miR-15a-5p cells possible mechanisms remains unclear. The present study explored expression human osteoporosis specimens during MC3T3-E1 cells. Functions were determined using...
Nonequilibrium dynamics of many-body systems is challenging for classical computing, providing opportunities demonstrating practical quantum computational advantage with analogue simulators. It proposed to be classically intractable sample driven thermalized states Bose-Hubbard systems, and further extract multi-point correlations characterizing phases. Here, leveraging dedicated precise manipulations number-resolved detection through a gas microscope, we implement 32-site Hubbard chain in...
Long-term or high-dose glucocorticoid use can lead to serious orthopedic complications, including femoral head necrosis. Both basic and clinical studies have shown that high doses dexamethasone (Dex) directly induce osteoblasts death. This study investigated the mechanism underlying Dex induced osteoblast In this study, we showed induces necroptosis, rather than apoptosis, through inhibition of AMP-activated protein kinase (AMPK) activity. We also demonstrated inactivation AMPK-mediated...
Featuring excellent coherence and operated parallelly, ultracold atoms in optical lattices form a competitive candidate for quantum computation. For this, massive number of parallel entangled atom pairs have been realized superlattices. However, the more formidable challenge is to scale-up detect multipartite entanglement due lack manipulations over local atomic spins retro-reflected bichromatic Here we developed new architecture based on cross-angle spin-dependent superlattice implementing...
The counterflow superfluidity (CSF) was predicted two decades ago. Counterintuitively, while both components in the CSF have fluidity, their correlated currents cancel out leading overall system to an incompressible Mott insulator. However, realizing and identifying remain challenging due request on extreme experimental capabilities a single setup. Here, we observe binary Bose mixture optical lattices. We prepare low-entropy spin-Mott state by conveying merging spin-1/2 bosonic atoms at...
We report on an experimental simulation of the spin-1 Heisenberg model with composite bosons in a one-dimensional chain based two-component Bose-Hubbard model. Exploiting our site-and spin-resolved quantum gas microscope, we observed faster superexchange dynamics system compared to its spin-1/2 counterpart, which is attributed enhancement effect multi-bosons. further probed non-equilibrium spin driven by and single-ion anisotropy terms, unveiling linear expansion spin-spin correlations,...
The classification model of osteoporosis was established, the diagnostic index system analyzed, and BP neural network designed. data 1261 people from 402 nuclear families were collected, including age, gender medical history. actual sampled tested by using computational function ANN, so that error could be controlled within a set range. results analysis suggested among 12 factors influencing bone mineral density, had most obvious effect, followed height, weight age. polymorphism estrogen...
Objective: To establish an interactive management model for community-oriented high-risk osteoporosis in conjunction with a rural community health service center. Materials and Methods: Toward multidimensional analysis of data, the system we developed combines basic principles data warehouse technology oriented to needs services. This paper introduces steps took constructing warehouse; case presented here is that district information Changshu, Jiangsu Province, China. For our warehouse,...
Background: Osteoporosis is the most common bone metabolic disease. Abnormal osteoclast formation and resorption play a fundamental role in osteoporosis pathogenesis. Recent researches have greatly broadened our understanding of molecular mechanisms osteoporosis. However, leading to are still not entirely clear. Objective: The purpose this work study critical regulatory genes, functional modules, signaling pathways. Methods: Differential expression analysis, network topology-based...