Lei Liu

ORCID: 0009-0001-5774-978X
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Research Areas
  • Acupuncture Treatment Research Studies
  • Autophagy in Disease and Therapy
  • Healthcare and Venom Research
  • Myofascial pain diagnosis and treatment
  • Rheumatoid Arthritis Research and Therapies
  • Wound Healing and Treatments
  • Pancreatic and Hepatic Oncology Research
  • Urinary Bladder and Prostate Research
  • Immune Response and Inflammation
  • Diabetic Foot Ulcer Assessment and Management
  • Ginseng Biological Effects and Applications
  • COVID-19 Clinical Research Studies
  • Blood groups and transfusion
  • Autoimmune and Inflammatory Disorders Research
  • High Altitude and Hypoxia
  • Lung Cancer Treatments and Mutations
  • Folate and B Vitamins Research
  • Urological Disorders and Treatments
  • PI3K/AKT/mTOR signaling in cancer
  • Natural Antidiabetic Agents Studies
  • Folklore, Mythology, and Literature Studies
  • Delphi Technique in Research
  • Influenza Virus Research Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Toxoplasma gondii Research Studies

Anhui University of Traditional Chinese Medicine
2003-2024

Affiliated Hospital of Jining Medical University
2023-2024

Army Medical University
2023

Fuyang Second People's Hospital
2009-2022

Meridian Institute
2021

Anhui Medical University
2021

Tang Du Hospital
2020

Rat models of DN were established using streptozotocin (STZ). The primary metabolic parameters assessed. pathological changes the rat kidney investigated, and RNA sequencing was performed for each group. Renal tissue apoptosis detected TUNEL assay. In rats high glucose- (Hg-) induced HK-2 cells, RT-qPCR western blot used to analyze expression related genes proteins. Hg medium establish diabetic environment. CCK-8 assay flow cytometry assess cell viability apoptosis, respectively....

10.1155/2023/4617653 article EN cc-by Journal of Diabetes Research 2023-08-16

OBJECTIVE To investigate the effect of moxibustion on wound healing, new capillaries and tissue repair in rats with full thickness skin excision. METHODS SD were randomly divided into control, moxa-fumigating moxa-heating groups, 24 each group. The full-thickness excision injury model was replicated according to Balaji's colleague's methods. Rats group received fumigation moxa-smog at surface (25 min/time) immediately after modeling through a smoke-heat separation device, those conventional...

10.13702/j.1000-0607.200750 article EN Acupuncture Research 2021-07-25

To observe the effect of moxibustion at "Zusanli "(ST36) on plasma amino acid metabolism in rats with knee osteoarthritis (KOA), and to explore mechanism repairing cartilage injury KOA.

10.13702/j.1000-0607.20230860 article EN PubMed 2024-08-25

The nasal-associated lymphoid tissues (NALTs), embedded in the submucosa of murine upper respiratory tract, represents an important site induction for local mucosal immune responses to airborne pathogens and intranasal vaccines. Here, we systematically investigated humoral cellular NALTs mice infected with A/Beijing/501/2009 (BJ501) A/Puerto Rico/8/1934 (PR8) viruses. Compared PR8 infection, BJ501 induced a more rapid increase virus-specific IgA IgG antibodies nasal lavage fluid higher ratio...

10.4149/av_2019_212 article EN Acta Virologica 2019-01-01

OBJECTIVE To observe the effect of moxibustion on phosphatidylinositol 3-kinase/protein kinase B/mammalian target rapamycin protein (PI3K/Akt/mTOR) signaling pathway in foot-pad synovial tissue rats with rheumatoid arthritis (RA), and to explore mechanism for treating RA. METHODS Forty healthy SD were randomly divided into a control group, model cigarette-moxibustion group medication 8 each group. The RA was established subcutaneous injection complete Freund's adjuvant (CFA) left hind under...

10.13703/j.0255-2930.20200112-k0003 article EN 2020-11-12

To observe the impact of moxa-stick with different diameters and at distances on skin temperature in local "Zusanli"(ST36) region, so as to select suitable specifications for moxibustion.A total 120 male SD rats were randomly divided into 0.5, 0.9, 1.2 1.8 cm, 1, 2, 3, 4 5 cm groups, 6 each group. Moxa-stick mentioned above was applied right ST36 (right hind limb) 10 min every time (between ignited tip skin) above, left used control point. The detected by using an infrared thermometer.After...

10.13702/j.1000-0607.190602 article EN PubMed 2020-05-25

Background: Although laboratory tests have become an indispensable part in clinical practice, its role severity classification and death risk-stratification of coronavirus disease-2019 (COVID-19) remains unvalidated. Methods: In 3342 hospitalized patients with COVID-19, those mild or moderate subtype were categorized into non-severe group, while severe critical group. Initial data analyzed compared according to disease outcome. Diagnostic models for group generated on risk factors identified...

10.2139/ssrn.3722066 article EN SSRN Electronic Journal 2020-01-01

Abstract Background: CKD management nurse specialists can effectively delay the progression of by starting from changing patients' lifestyles and improving their self-management ability. Chronic kidney disease requires more comprehensive theoretical knowledge as well skills, therefore there is an urgent need to train a group multi-skilled specialist nurses. However, are few specific indicators that be used assess core competencies these Therefore, this study aimed construct competency...

10.21203/rs.3.rs-3256896/v1 preprint EN cc-by Research Square (Research Square) 2023-08-25

To analyze the reasons for ABO blood group forward typing and reverse incompatibility of proband by serological molecular biological tests, so as to clarify genetic rules determine reasonable transfusion strategy.On basis testing results, PCR-SSP method was utilized exon sequencing in peripheral 5 family members, results were comprehensively analyzed.The incompatibility, test showed that there a c.700C>G mutation compared with B101, which consistent B(A)02 subtype, genotype B(A)02/O02. The...

10.19746/j.cnki.issn.1009-2137.2022.06.034 article EN PubMed 2022-12-01

To observe the effect of long-term inhalation moxa-smoke on olfactory epithelial cells in rats, order to explore safety (MSI).A total 32 SD rats (half male and half female) were randomly divided into 4 groups: normal, low concentration (LCMSI), medium (MCMSI) high (HCMSI), with 8 each group. Rats LCMSI, MCMSI HCMSI groups put closed boxes which filled ignited moxa stick-released smoke at concentrations (0.11±0.05)mg/m3, (0.23±0.05) mg/m3 (0.53±0.05)mg/m3, respectively. The treatment was...

10.13702/j.1000-0607.200968 article EN PubMed 2021-10-25
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