Cheng Chen

ORCID: 0000-0001-9239-9490
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About
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Research Areas
  • Optical Imaging and Spectroscopy Techniques
  • Non-Invasive Vital Sign Monitoring
  • Photoacoustic and Ultrasonic Imaging
  • EEG and Brain-Computer Interfaces
  • Childhood Cancer Survivors' Quality of Life
  • Family Support in Illness
  • Analytical Chemistry and Sensors
  • Acute Lymphoblastic Leukemia research
  • Functional Brain Connectivity Studies
  • Epigenetics and DNA Methylation
  • Thyroid Cancer Diagnosis and Treatment
  • Textile materials and evaluations
  • Urban Stormwater Management Solutions
  • Optical Coherence Tomography Applications
  • Geometric Analysis and Curvature Flows
  • FOXO transcription factor regulation
  • Wound Healing and Treatments
  • Robotic Path Planning Algorithms
  • CCD and CMOS Imaging Sensors
  • Control and Dynamics of Mobile Robots
  • Color perception and design
  • Congenital Diaphragmatic Hernia Studies
  • Flood Risk Assessment and Management
  • UAV Applications and Optimization
  • Advanced Optical Sensing Technologies

Shanghai Jiao Tong University
2008-2024

Nanjing University of Information Science and Technology
2024

Second Affiliated Hospital of Soochow University
2024

St. Jude Children's Research Hospital
2024

Neusoft (China)
2024

Chengdu Neusoft University
2024

Soochow University
2024

The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
2024

Shandong University
2024

Heze Municipal Hospital
2024

This paper presents a dynamic optical phantom for the simulation of metabolic activities in brain, and linear equivalent model is built control voltage versus substance concentration. A solid–solid realized by using liquid crystal film as voltage-controlled light intensity regulator on surface basic phantom, which uses epoxy resin matrix material nanometer carbon powder titanium dioxide absorption scattering dopants, respectively. The could mimic near-infrared spectrum (NIRS) signals with...

10.34133/cbsystems.0047 article EN cc-by Cyborg and Bionic Systems 2023-01-01

Current research in epigenetic age acceleration (EAA) is limited to non-Hispanic White individuals. It imperative improve inclusivity by considering racial and ethnic minorities EAA research.

10.1001/jamanetworkopen.2024.19771 article EN cc-by-nc-nd JAMA Network Open 2024-07-02

Functional near-infrared spectroscopy (fNIRS) is a powerful medical imaging tool in brain science and psychology, it can also be employed brain-computer interface (BCI) due to its noninvasive artifact-less-sensitive characteristics. Conventional ways detect large-area activity using (NIR) technology are based on Time-division or Frequency-division modulation technique, which traverses all physical sensory channels specific period. To achieve higher resolution brain-tasks classification...

10.1109/tbcas.2022.3149766 article EN IEEE Transactions on Biomedical Circuits and Systems 2022-02-01

Abstract Nerve growth factor ( NGF ) and its receptor, tropomyosin receptor kinase A TrkA ), are known to play important roles in the immune nervous system. However, effects of on osteogenic differentiation dental pulp stem cells DPSCs remain unclear. This study aimed investigate role vitro underlying mechanisms. were cultured medium containing (50 ng/ mL for 7 days. Then osteogenic‐related genes protein markers analysed using qRT‐PCR Western blot, respectively. Furthermore, addition...

10.1111/jcmm.18143 article EN cc-by Journal of Cellular and Molecular Medicine 2024-02-01

This paper presents a multichannel functional continuous-wave near-infrared spectroscopy (fNIRS) system, which collects data under dual-level light intensity mode to optimize SNR for channels with multiple source-detector separations. system is applied classify different cortical activation states of the prefrontal cortex (PFC). Mental arithmetic, digit span, semantic task, and rest state were selected as four mental tasks. A deep forest algorithm employed achieve high classification...

10.1155/2020/1567567 article EN cc-by Journal of Sensors 2020-06-12

Motivation: This paper proposes a motion artifact removal (MAR) algorithm and its evaluation method for wearable functional near infrared spectroscopy (fNIRS) system. Methods: Two types of artifacts (MAs) their characteristics have been investigated, coarse/fine dual-stage MAR is proposed, which can remove the MAs with different features magnitudes to protect original data from damage. In addition, an also proposed based on classification 4 mental tasks, objectively quantize performance...

10.1109/jsen.2021.3069553 article EN IEEE Sensors Journal 2021-03-29

10.1016/j.bulsci.2008.12.001 article EN publisher-specific-oa Bulletin des Sciences Mathématiques 2008-12-26

This paper presents a low-power frequency-domain functional near-infrared spectroscopy (FD-fNIRS) readout circuit for the absolute value measurement of tissue optical characteristics. The proposes mixer-first analog front-end (AFE) structure and 1-bit Σ-Δ phase-to-digital converter (PDC) to reduce required bandwidth laser modulation frequency, thereby saving power while maintaining high resolution. proposed chip achieves sub-0.01° phase resolution consumes 6.8 mW power. Nine solid phantoms...

10.1109/tbcas.2024.3372887 article EN IEEE Transactions on Biomedical Circuits and Systems 2024-03-07

The non-invasive quantification of metabolite concentration is significant importance in the fields medical diagnosis and monitoring. Functional near-infrared spectroscopy (NIRS) offers a promising optical solution for this purpose. However, conventional continuous-wave (CW) NIRS systems only record light intensity, limiting analysis absorption (μ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">a</inf> ) reduced scattering...

10.1109/isscc49657.2024.10454486 article EN 2022 IEEE International Solid- State Circuits Conference (ISSCC) 2024-02-18

Abstract Background: A genetic variant (rs3824662) at GATA3 was previously associated with risk of Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) and relapse. Our recently published childhood Hodgkin lymphoma (HL) study identified a genome-wide significant association for another (rs3781093) in high linkage disequilibrium (D’=1.0, R2=0.91) rs3824662. We hypothesize that is pleiotropic locus multiple cancers. Methods: The performed by combining 3 cohorts cancer...

10.1158/1538-7445.am2024-6618 article EN Cancer Research 2024-03-22

10.1109/biocas61083.2024.10798374 article EN 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS) 2024-10-24

As an emerging category of brain-computer interface technology, functional near-infrared spectroscopy (fNIRS) has garnered significant attention due to its non-invasiveness, portability, and energy efficiency. However, the efficient design optimization circuits for complex fNIRS systems remain unresolved challenges in field. In this study, we propose RTE-based compact model simulating light propagation biological tissues, serving as effective tool aid signal chain systems. The paper begins...

10.1109/biocas58349.2023.10389150 article EN 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS) 2023-10-19

This demonstration presents a wearable fNIRS system for mental status assessment. Through the combined use of with VFT, provides an effective approach monitoring brain activity and assessing status. Furthermore, employs spatial adaptive sampling method, which increases its energy efficiency without significant reduction on functional imaging quality.

10.1109/biocas58349.2023.10388591 article EN 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS) 2023-10-19

Objective To investigate the clinicopathological features and surgical treatment for Hashimoto thyroiditis (HT)concomitant with thyroid papillary carcinoma(PTC).Methods The clinical data in 128 cases of PTC including 30 HT concomitant treated surgically diagnosis confirmed pathologically from Jan 2009 to Dec 2010 were retrospectively analyzed.Results incidence carcinoma was 6.5 times higher among women than men.Rates central lymph node metastasis without 46.7% 39.4%,respectively.Rates...

10.3760/cma.j.issn.1007-631x.2013.07.008 article EN 2013-07-25

This demonstration shows a continuous-wave near-infrared spectroscopy (NIRS) system with multiple channels, which contains sixteen detectors and light sources. The is applied to classify three different cortical activation states of the prefrontal cortex (PFC) in this demonstration. Due its benefits on non-invasive monitoring high temporal resolution, NIRS an promising candidates for brain imaging natural situations. In demonstration, visitors can intuitively understand potential terms...

10.1109/biocas.2019.8918748 article EN 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS) 2019-10-01

This paper presents a frequency-domain functional near-infrared spectroscopy readout circuit for absolute value measurement of tissue optical characteristics. A mixer-first analog front-end (AFE) structure and 1-bit <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\Sigma-\Delta$</tex> phase-to-digital converter (PDC) are proposed to lower both the required bandwidth laser modulation frequency save power while maintain high resolution. The IC...

10.1109/esscirc55480.2022.9911433 article EN ESSCIRC 2022- IEEE 48th European Solid State Circuits Conference (ESSCIRC) 2022-09-19
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