A5000073602- Plasma Diagnostics and Applications
- Mitochondrial Function and Pathology
- Spine and Intervertebral Disc Pathology
- RNA and protein synthesis mechanisms
- Genomics and Phylogenetic Studies
- Spinal Fractures and Fixation Techniques
- dental development and anomalies
- Semiconductor materials and devices
- Photosynthetic Processes and Mechanisms
- Laser-induced spectroscopy and plasma
- Pancreatic and Hepatic Oncology Research
- Oral and Maxillofacial Pathology
- Facial Trauma and Fracture Management
- Metal and Thin Film Mechanics
- Protein Structure and Dynamics
- Bacterial Genetics and Biotechnology
- ATP Synthase and ATPases Research
- Dental Radiography and Imaging
- Pelvic and Acetabular Injuries
- Inflammasome and immune disorders
- Laser-Plasma Interactions and Diagnostics
- Particle accelerators and beam dynamics
- Orthopedic Surgery and Rehabilitation
- Cancer Genomics and Diagnostics
- Scoliosis diagnosis and treatment
Veterinary Medicines Directorate
2025
Monash University
2010-2024
Willows Veterinary Centre and Referral Service
2024
University of Winchester
2024
British Veterinary Association
2024
Axiom (United States)
2024
Royal Veterinary College
2024
Australian Regenerative Medicine Institute
2023
Vanderbilt University Medical Center
2023
The University of Texas Health Science Center at Houston
2022
The ability to catalytically cleave protein substrates after synthesis is fundamental for all forms of life. Accordingly, site-specific proteolysis one the most important post-translational modifications. key understanding physiological role a protease identify its natural substrate(s). Knowledge substrate specificity can dramatically improve our predict target substrates, but this information must be utilized in an effective manner order efficiently by silico approaches. To address problem,...
The results of a study the mode transitions in helicon source when used geometry required for plasma processing are presented. We find that basic characteristics high density (>5×1011 cm−3 chamber at 500 W) and low potential (∼15 V) observed this configuration. can be interpreted terms dispersion relation wave. A initial breakdown has also been made have aided understanding operation during pulsed etching.
The mitosomes of Giardia intestinalis are thought to be mitochondria highly-reduced in response the oxygen-poor niche. We performed a quantitative proteomic assessment increase understanding function and evolutionary origin these enigmatic organelles. Mitosome-enriched fractions were obtained from cell homogenate using Optiprep gradient centrifugation. To distinguish mitosomal proteins contamination, we used shot-gun strategy based on isobaric tagging peptides with iTRAQ tandem mass...
Abstract Objective The intricate neuroanatomical structure of the cerebellum is longstanding interest in epilepsy, but has been poorly characterized within current corticocentric models this disease. We quantified cross‐sectional regional cerebellar lobule volumes using structural magnetic resonance imaging 1602 adults with epilepsy and 1022 healthy controls across 22 sites from global ENIGMA‐Epilepsy working group. Methods A state‐of‐the‐art deep learning‐based approach was employed that...
A 13.56 MHz rf inductively coupled diffusion plasma confined by a weak magnetic field is shown to produce high etch rates and densities. With substrate bias of −160 V 1 mTorr pure SF6, silicon has been etched anisotropically at rate 0.7 μm min−1 with selectivity SiO2 about 5.
Background: Spinal growth modulation by tethering the anterolateral aspect of spine, as previously demonstrated in a nonscoliotic calf model, may be viable fusionless treatment method for idiopathic scoliosis. The purpose present study was to evaluate radiographic, histologic, and biomechanical results after six twelve months spinal porcine model with rate similar that adolescent patients. Methods: Twelve seven-month-old mini-pigs underwent instrumentation vertebral staple-screw construct...
Trichomonas vaginalis is a parasitic protist of the Excavata group. It contains an anaerobic form mitochondria called hydrogenosomes, which produce hydrogen and ATP; majority mitochondrial pathways organellar genome were lost during mitochondrion-to-hydrogenosome transition. Consequently, all hydrogenosomal proteins are encoded in nucleus imported into organelles. However, little known about membrane machineries required for biogenesis organelle metabolite exchange. Using combination mass...
The mitochondrial inner and outer membranes are composed of a variety integral membrane proteins, assembled into the posttranslationally. small translocase (TIMs) group ∼10 kDa proteins that function as chaperones to ferry imported across intermembrane space membranes. In yeast, there 5 TIM proteins: Tim8, Tim9, Tim10, Tim12, Tim13, with equivalent reported in humans. Using hidden Markov models, we find many eukaryotes have Tim8 Tim13 Tim9 Tim10 subunits. Some provide "snapshots" evolution,...
Summary The β‐barrel assembly machine (BAM) complex is an essential feature of all bacteria with outer membrane. core subunit the BAM BamA and, in Escherichia coli , four lipoprotein subunits: BamB, BamC, BamD and BamE, also function complex. Hidden Markov model analysis was used to comprehensively assess distribution subunits lipoproteins across subclasses proteobacteria. A patchwork detected which readily reconciled evolution α‐, β‐, γ‐, δ‐ ε‐proteobacteria. Our findings lead a proposal...
Tsyganov et al., (2018). RNAsik: A Pipeline for complete and reproducible RNA-seq analysis that runs anywhere with speed ease . Journal of Open Source Software, 3(28), 583, https://doi.org/10.21105/joss.00583
The temporal evolutions of the ion and electron energy distributions pulsed helicon diffusion plasmas are measured. High power (<1 kW) moderate length (10 ms pulses, 10% duty cycle) 13.56 MHz RF discharges show three distinct pulse phases: (a) breakdown (the first ), characterized by high temperatures (>8 eV) energies (>40 eV); (b) a mid-pulse phase, which is identical to CW operation, (c) termination afterglow displays collapsing plasma potential, splitting in peaks transient hot component...
A compact retarding field ion energy analyzer has been designed and built to measure the distribution of ions bombarding wafer surfaces placed on radio frequency (rf) biased electrodes in high-density plasma reactors. The was used impinging rf-biased electrostatic chuck a transformer coupled (TCP) reactor. effects TCP power, rf bias, gas composition, mass distributions (IEDs) were demonstrated through Ar, Ne, Ar/Ne, O2 CF4/O2 discharges. In operating range studied, average increased linearly...
Molecular machines drive essential biological processes, with the component parts of these each contributing a partial function or structural element. Mitochondria are organelles eukaryotic cells, and depend for their biogenesis on set molecular protein transport. How evolved is fundamental question. were derived from an alpha-proteobacterial endosymbiont, we identified in alpha-proteobacteria mitochondrial transport machine. In bacteria, components found inner membrane, topologically...