A5029698079- Food Quality and Safety Studies
- Gut microbiota and health
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Inflammatory Bowel Disease
- Natural product bioactivities and synthesis
- Nutrition, Health and Food Behavior
- Genomics, phytochemicals, and oxidative stress
- Diet and metabolism studies
- Nutritional Studies and Diet
- Health and Wellbeing Research
- Agriculture, Soil, Plant Science
- Bioactive Compounds and Antitumor Agents
- Garlic and Onion Studies
- Streptococcal Infections and Treatments
- Research in Cotton Cultivation
- Potato Plant Research
- Plant-derived Lignans Synthesis and Bioactivity
- Chromatography in Natural Products
- Food Science and Nutritional Studies
- Central Venous Catheters and Hemodialysis
- Immune Response and Inflammation
- Phytochemistry and Biological Activities
- Venous Thromboembolism Diagnosis and Management
- Edible Oils Quality and Analysis
Rural Development Administration
2017-2023
Instituto de Ciencias Agrarias
2023
National Institute of Agricultural Science and Technology
2022
National Academy of Agricultural Science
2017-2021
Korea University
2021
Yonsei Sarang Hospital
2014
We investigated associations of habitual dietary intake with the taxonomic composition and diversity human gut microbiota in 222 Koreans aged 18-58 years a cross-sectional study. Gut data were obtained by 16S rRNA gene sequencing on DNA extracted from fecal samples. The diet for previous year was assessed food frequency questionnaire. After multivariable adjustment, several groups including vegetables, fermented legumes, dairy products, processed meat, non-alcoholic beverages associated...
In this study, we investigated the effects of radish sprout ethanol extract (RSE) on inflammatory responses in macrophages and a mouse model colitis. RSE administration was found to effectively inhibit phosphorylation IκB and, turn, production pro-inflammatory enzymes cytokines lipopolysaccharide-stimulated macrophages. dextran sulfate sodium (DSS)-colitis mice, prevented body weight colon length reduction, while decreasing inflammation mucosal necrosis. The diversity fecal microbiota...
Background: Edible flowers, Tropaeolum majus has been used as a disinfectant and an antibiotic, for wound healing, but the anti-obesity effects of this plant have not reported previously Objective: We investigated anti-adipogenic T. ethanol extract (TME) on 3T3-L1 cells. Design: cells were differentiated in presence different concentrations TME. Lipid accumulation levels determined using Oil-Red O staining triglyceride content assay. Changes expression proteins related to adipocyte...
Diet has a profound impact on the progression of metabolic syndrome (MetS) into various diseases. The gut microbiota could modulate effect diet health. We examined whether dietary patterns related to MetS differed according microbial enterotypes among 348 Korean adults aged 18–60 years recruited between 2018∼2021 in cross-sectional study. enterotype each participant was identified based 16S rRNA data. main pattern predicting (MetS-DP) derived using reduced-rank regression (RRR) models. In...
Oenanthe javanica, commonly known as water dropwort, has long been used to treat acute and chronic hepatitis, abdominal pain, alcohol hangovers, inflammation in various traditional medicine systems Asia. However, whether O. javanica beneficial effects on colitis-induced intestinal damage remains elusive. This study tested the hypothesis that anti-inflammatory antioxidant activities mice with dextran sulfate sodium (DSS)-induced colitis. First, treatment of ethanol extract (OJE) inhibited...
딸기 과실과 설탕 이외에 젤리화 형성에 영향을 주는 산, 펙틴 등을 따로 첨가하지 않고 딸기와 설탕의 배합비를 달리한 잼의 품질특성을 조사하였다. 딸기를 70~30% 수준으로 감소한 처리구의 당도는 <TEX>$59.00{\sim}77.33^{\circ}Brix$</TEX>, pH는 4.17~4.28으로 증가한 반면, 총산도는 1.55~0.31%로 감소하였다. 함량이 줄어드는 S1~S5 L값은 5.36~30.83, a값은 27.83~37.19, 그리고 b값은 9.08~40.52로 모두 증가하였다. 줄어들수록 딸기잼의 안토시아닌 함량과 함량은 각각 9.91~5.15 mg/g, 4.86~1.46 mg/g으로 첨가량에 따른 물성 측정 결과에서도 hardenss, gumminess 및 chewiness은 첨가 수준이 낮아지는 glucose, fructose 감소된 반면 sucrose 유기산 구성은 oxalic aicd, citric acid, malic succinic acid...
Abstract Antirrhinum majus (AM) has attracted attention as a rich source of phytochemicals, which are beneficial for human health. However, the anti‐inflammatory effects AM have not been studied scientifically. Therefore, we investigated antioxidative properties and extract (AME) in lipopolysaccharide (LPS)‐stimulated RAW 264.7 macrophages. AME showed high radical‐scavenging ability. Viability cells was significantly altered by at concentrations 0–300 µg/ml. LPS‐induced nitric oxide (NO)...
녹차의 성분은 폴리페놀, 알칼로이드, 아미노산 및 기타 화합물로 구성되어 있고 카테킨과 카페인의 함량은 품질 평가 기준으로 알려져 있다. 본 연구에서는 ultra performance liquid chromatography(UPLC)를 이용하여 지표성분 epicatechin, epigallocatechin, epicatechin gallate, epigallocatechin gallate 카페인을 동시 분석하였다. 최적 추출조건으로는 25% 에탄올을 온도 25°C, 1시간 추출하였고, UPLC를 이용한 빠르고 간편한 분석조건을 확립하고 정확성, 정밀성, 직선성, 특이성 등 분석법의 유효성을 검증하였다. 지역별로 녹차 잎을 추출하여 UPLC로 카테킨 화합물 함량을 분석한 결과 총 카테킨의 함량(mg/g, 건조 중량)은 제주도 168.87 mg/g 경상남도 156.75 전라남도 148.22 순으로 존재하였고 약 7.3~26.1 mg/g의 카페인이 함유되어 지역별 생육환경에 따라...
This study investigated the antioxidant capacities and inhibitory activity of peeled lotus root (Nelumbo nucifera) as a food material on angiotension-converting enzyme (ACE). The effects total polyphenol flavonoid contents were not signicant. However, DPPH radical scavenging decreased from 85.07% to 80.70% by treatment. SOD-like 20.84% 17.97%, ACE 53.4% 50.1% treatement. Thus, consumption non-peeled should increase.
본 연구는 재배지역별 오미자의 리그난 함량을 조사하기 위해 수행되었다. HPLC를 사용하여 특이성, 직선성, 검출한계(LOD), 정량한계(LOQ) 및 정확도를 결정함으로써 리그난의 분석법이 검증되었다. 중에는 schizandrin이 3.85~6.60 mg/g으로 가장 풍부했고 그다음 gomisin N이 2.69~4.38 많았다. Schizandrin A와 A는 0.60~2.04, 0.86~1.63 mg/g이었고, G, H, J는 0.5 mg/g 미만이었다. 화합물 7종 함량은 9.04~14.90 mg/g이었다. 오미자는 각 다르지만 전체 함량에는 큰 차이가 없다. 오미자 표준화를 위한 기초자료로 유용할 것으로 기대된다.
Cellulitis and deep vein thrombosis (DVT) have similar symptoms (lower extremity pain, erythema, swelling) there is the potential for misdiagnosis.In cases of cellulitis, DVT should be ruled out, as cellulitis might mask those DVT, leading to serious complications such pulmonary thromboembolism.The reported incidence in patients with low, especially progression thromboembolism.We present a case thromboembolism following lower leg 54-year-old male.(
The purpose of this study was to validate an analytical method for assessing the anthocyanin content in mulberry.The ultra-performance liquid chromatography (UPLC) validated accordance with International Conference on Harmonization guidelines procedures respect specificity, precision, accuracy, and linearity.The correlation coefficient values cyanidin-3-glucoside (C3G) cyanidin-3-rutinoside (C3R) were 1,000 0.999 respectively, 0.20 0.60 μg/mL respectively C3R.The analysis mulberry cultivars...
Abstract Background : Little is known of the relationship between Korean habitual diet and gut microbiota composition. We investigated associations dietary intake foods nutrients with taxonomic composition diversity in 222 adults aged 18-58 years a cross-sectional study. Gut microbial data were obtained by 16S rRNA gene sequencing bacterial DNA extracted from fecal samples. Habitual for previous year was collected validated food frequency questionnaire. Correlations intakes examined...
Procyanidin is known for its antioxidant and anti-inflammatory effects.Using HPLC analysis, we found that the content of procyanidin B2 nine times higher in unripe apples than ripe apples.This study, therefore, investigates effects apple ethanol extraction (UAE) on colitis mice.The intact intestinal epithelium channel nutrient absorption crucial maintaining good health.We simulated mice by inducing impairment epithelium-using dextran sodium sulfate.The efficacy UAE administration promoting...
본 연구에서는 고지방식이로 유도된 비만쥐 모델에서 금어초 추출물의 지질대사 개선, 혈당조절, 항염증 효과를 보고자 하였다. 이를 위해 C57BL/6 마우스에서 8주간 추출물을 경구투여 한 후 임상적 지표로 체중 변화, 장기무게, 혈중 지질, 혈당, GTT, ITT, 염증 사이토카인, 염증관련 단백질의 발현 정도를 조사하였다. 그 결과 추출물은 간, 복부피하지방의 무게를 효과적으로 감소시켰으며, 이는 인한 비만 개선에 추출물이 긍정적인 영향을 미치는 것으로 판단된다. 또한 투여는 중성지방과 총 콜레스테롤 그리고 간세포 손상으로 AST 효소의 혈액 내 유출을 감소시켜 비만상태의 이상과 간 손상을 최소화하는 생각된다. 비만으로 혈당조절 장애 대한 알아보기 위하여 글루코오스와 인슐린 농도, 내당능, 내성을 확인하였다. 유의적으로 글루코오스 농도를 감소시키고 인위적으로 투입된 인슐린에 대해서도 혈당 조절 보였다. 비만에서 나타나는 만성적인 염증상태에 개선 알아보고자 MCP-1,...