A5004809951- Catalytic C–H Functionalization Methods
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and Catalytic Reactions
- Sulfur-Based Synthesis Techniques
- Cyclopropane Reaction Mechanisms
- Asymmetric Hydrogenation and Catalysis
- Synthesis and biological activity
- Crystallography and molecular interactions
- Higher Education and Teaching Methods
- Catalytic Alkyne Reactions
- Synthesis of heterocyclic compounds
- Synthesis and Biological Evaluation
- Crystal structures of chemical compounds
- Food Safety and Hygiene
- Garlic and Onion Studies
- Supramolecular Chemistry and Complexes
- Tuberculosis Research and Epidemiology
- Biotechnology and Related Fields
- Pharmacological Effects of Natural Compounds
- Vanadium and Halogenation Chemistry
- Phytochemicals and Antioxidant Activities
- Organoboron and organosilicon chemistry
- Biomedical and Engineering Education
- Advanced Synthetic Organic Chemistry
Yichun University
2025
Hunan University of Science and Engineering
2009-2024
South China University of Technology
2015-2016
Guangdong Pharmaceutical University
2009
Henan University of Technology
2005
Henan Radio and Television University
2002
Copper(I)-catalyzed 5-sulfonation of quinolines via bidentate-chelation assistance has been developed. The reaction is compatible with a wide range quinoline substrates and arylsulfonyl chlorides. Experimental theoretical (DFT) investigation implicated that single-electron-transfer process involved in this sulfonylation transformation.
Abstract For the first time, a highly regioselective intermolecular sulfonylamidation unactivated secondary Csp 3 −H bond has been achieved using Ir III catalysts. The introduced N , ’‐bichelating ligand plays crucial role in enabling iridium–nitrene insertion into via an outer‐sphere pathway. Mechanistic studies and density functional theory (DFT) calculations demonstrated that two‐electron concerted nitrene was involved this amidation process. This method tolerates broad range of linear...
An efficient one-pot and transition-metal-free chlorocyclization cascade of 2-aminopyridines with aliphatic carboxylic acids is reported. This transformation provides a novel approach to 2-chloro- or 3-chloro-substituted imidazo[1, 2-α]pyridines broad range substrate scopes.
A Rh(iii)-catalyzed cross-coupling/cyclization cascade of α-imino Csp(3)-H bonds with donor/acceptor α-acyl diazocarbonyl compounds has been developed. This novel transformation involves ligand-directed bond functionalization carbenoids under the pyridine-chelation assistance, and offered an efficient access to synthetically versatile polysubstituted N-(2-pyridyl)pyrroles a broad range functional group tolerance.
Host 1 with an electron-deficient nanometer-sized cavity were synthesized in two steps. Moreover, has been successfully used as a gas chromatographic stationary phase to prepare packed column for the separation of PhH/Cy and Tol/MCy.
We first report the direct ortho C-H amidation of arenes with azides by using a novel and inexpensive RuHCl(CO)(PPh3)3 catalyst. The reaction proceeds efficiently in high yield over broad range substrates without requirement any additional silver salt or additive.
A direct and efficient palladium-catalyzed reductive coupling reaction of nitroarenes with phenols has been developed. series N-cyclohexylaniline derivatives was easily efficiently obtained in moderate to good yields via C–N bond formation by the simple use safe inexpensive sodium formate as hydrogen donor.
Abstract For the first time, a highly regioselective intermolecular sulfonylamidation unactivated secondary Csp 3 −H bond has been achieved using Ir III catalysts. The introduced N , ’‐bichelating ligand plays crucial role in enabling iridium–nitrene insertion into via an outer‐sphere pathway. Mechanistic studies and density functional theory (DFT) calculations demonstrated that two‐electron concerted nitrene was involved this amidation process. This method tolerates broad range of linear...
An efficient copper-catalyzed, quinolyl N-directed nitrene transfer reaction to 8-quinolylsulfides was described. A variety of 8-quinolylsulfimides with different functional groups were synthesized in moderate high yields. The obtained proved be promising novel type bidentate ligands Pd(II)-catalyzed allylic alkylation.
Abstract Iodination and O ‐arylation of 2‐arylquinolin‐4(1 H )‐one with PIDA under mild conditions have been developed, in which play a dual role as an iodine source aryl source. This protocol provides facile access to 3‐iodo‐4‐phenoxy‐2‐arylquinolines tolerance broad range functional groups. Furthermore, method is employed for concise synthesis topoisomerases catalytic inhibitor analogue.
Abstract A copper(I)‐catalyzed addition of alkylborane reagents to α‐iminoacetates has been developed assemble both acyclic and cyclic α‐branched α‐amino carboxylic acid derivatives in good yields. wide variety unactivated alkenes are well tolerated this transformation. magnified image
Objective To evaluate overall hazard of tuberculosis.Methods The value Disability ad-justed life years(DALY)of uberculosis was calculated using the formula recommended by WHO.Results It found that 833367 health lives lost due to tuberculosis.Conclusion index DALY included more signification than orthodox indexes.DALY should be internalized into national regular disease surveillance system. Key words: Tuberculosis; Disability adjusted years; disease burden
Abstract via bidentate‐chelation assistance
An efficient protocol has been developed for Cu-promoted C–S coupling reactions by using triarylbismuths or triarylantimonys as arylating reagents with remarkable functional group tolerance and chemoselectivity.