A5101536584- Silkworms and Sericulture Research
- Silk-based biomaterials and applications
- Crustacean biology and ecology
- Fish Biology and Ecology Studies
- Autophagy in Disease and Therapy
- Air Quality and Health Impacts
- Land Use and Ecosystem Services
- Cancer-related molecular mechanisms research
- Rural development and sustainability
- Biochemical effects in animals
- Plant tissue culture and regeneration
- Magnetic Properties and Applications
- Electric Motor Design and Analysis
- Advanced Glycation End Products research
- Energy, Environment, Economic Growth
- Research in Cotton Cultivation
- Intracerebral and Subarachnoid Hemorrhage Research
- Medical and Biological Ozone Research
- Acupuncture Treatment Research Studies
- Climate change impacts on agriculture
- Plant responses to water stress
- Sensorless Control of Electric Motors
- Wnt/β-catenin signaling in development and cancer
- Drug Solubulity and Delivery Systems
- Infant Nutrition and Health
Shantou University
2025
Sichuan University
2014-2024
West China Medical Center of Sichuan University
2024
First Affiliated Hospital of Chengdu Medical College
2018-2024
Hangzhou Dianzi University
2024
Guangxi Medical University
2019-2024
First Affiliated Hospital of Zhengzhou University
2023
Central Hospital of Wuhan
2023
Huazhong University of Science and Technology
2023
Harbin Medical University
2020
Diesel exhaust particles (DEPs) are common airborne ultrafine (UFPs); however, few studies have examined their effects on the gastrointestinal tract. To investigate interaction of gut microbiota and DEPs-induced colonic injury, adult C57BL/6 mice kept in whole-body inhalation chambers exposed to filtered room air (FRA) or DEPs (300 µg m-3) 1 h per day for 28 consecutive days. exposure results colon epithelial injury with inflammatory cell infiltration mucus depletion. Abundance Lactobacillus...
Brassinosteroids (BRs) are growth-promoting plant hormones that play a crucial role in biotic stress responses. Here, we found BR treatment increased nitric oxide (NO) accumulation, and significant reduction of virus accumulation Arabidopsis thaliana. However, the plants pre-treated with NO scavenger [2-(4-carboxyphenyl)-4,4,5,5-tetramethyl-imidazoline-1-1-oxyl-3-oxide (PTIO)] or nitrate reductase (NR) inhibitor (tungstate) hardly had any generation appeared to have highest viral replication...
Abstract Apart from the influences of wind and tides, upwelling can also modulate dispersal dynamics river plumes. However, specific responses to processes over inner shelf remain unclear. This study employs a numerical model investigate effects northeastern South China Sea its barotropic on freshwater transport medium‐scale plume. In experiment with extremely weakened (tiny case), plume water spreads across wide coastal region driven by upwelling‐favorable winds. With upwelling, occupies...
In rodents, the amygdala has been proposed to serve as a key center for nociceptive perception. Previous studies have shown that extracellular signal-regulated kinase (ERK) signaling cascade in central nucleus of (CeA) played functional role inflammation-induced peripheral hypersensitivity. Duloxetine (DUL), serotonin and noradrenaline reuptake inhibitor, produced analgesia on formalin-induced spontaneous pain behaviors. However, it is still unclear whether single DUL pretreatment influences...
The incidence rate of thyroid cancer, the most common endocrine malignancy, has increased rapidly over past 10 years. However, fundamental molecular mechanisms underlying malignant progression cancer are unclear.Firstly, quantitative real-time PCR analysis and Western blot were used to investigate expression Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 (CITED1) in papillary carcinoma (PTC) cell lines. Then, we investigated effects CITED1 knockdown on...
Mitochondria is a double membrane-bound cellular organelle that generates energy to maintain the homeostasis of cells. Immunity-related GTPase M (IRGM) in human locates at inner membrane mitochondria and best known for its role regulating autophagy against intracellular pathogens. Previous studies have shown IRGM crucial normal function mitochondria, yet, molecular mechanisms underlying IRGM-mediated quality control are still not fully understood. In this study, we showed knocking-down...
Manganese (Mn) is an essential micronutrient required for various biological processes but excess exposure to Mn can cause neurotoxicity. However, there are few reports regarding the toxicity effect of on kidney as well underlying molecule mechanism. Herein, in vivo experiments were adopted assess effects associated with Mn, and found that chronic treatment induced injury glomerular podocytes not renal tubule rats. Genome-wide CRISPR/Cas9 knockout screen was then employed explore biotargets...
Acute alcohol intoxication (AAI) is a life-threatening medical condition resulting from excessive consumption. Our research revealed the potential of morin (MOR) in treating AAI. However, MOR's effectiveness against AAI was hindered by its poor solubility water and low bioavailability. In this study, our aim to develop self-nanoemulsifying drug delivery system (SNEDDS) enhance bioavailability, evaluate anti-AAI effects, investigate underlying mechanism.
To explore the epidemiology of patients with spontaneous intracerebral hemorrhage (sICH) in Chengdu, China, we retrieved data cerebral admitted to First Affiliated Hospital Chengdu Medical College from January 2017 December 2019. We performed a comprehensive analysis location hemorrhage, demographics, factors condition body, severity disturbance consciousness, treatment, length stay (days), inpatient costs, prognosis, and mortality rate sICH. In total, 561 sICH were included. The site was...
Previously, we showed that mouse immunity-related guanosine triphosphatase (GTPase) family M protein 1 (Irgm1) promotes malignant melanoma progression by inducing cellular autophagy flux and metastasis. Human IRGM, a truncated functionally distinct from its counterpart, has several splice isoforms. In this study, analyzed the association of IRGM human clinical prognosis investigated function in cells. Data training cohort (n = 144) overexpression is proportional to genesis stages tissue...
Abstract Twenty-seven sets of simple sequence repeat (SSR) primers were developed through hybridizing (CA)n, (CT)n and (GT)n sequencing the positive clones in libraries constructed by using p50 silkworm strain. Of those primer pairs, 26 SSR amplified well two regional wild strains. Ten domesticated strains used for comparing polymorphisms constructing a phylogenetic tree employing UPGAM method. The result showed that genetic distances within Japanese are closer than Chinese And this also...
Abstract An amplification fragment length polymorphism (AFLP) molecular linkage map with a relatively high density for location of quantitative trait loci (QTLs) controlling the traits silkworm ( Bombyx mori ) cocoons, was constructed using 91 individuals F 2 generation. Among 692 effective loci, 550 were allocated to subgroups and b, which 21 groups in subgroup had 233 markers 28 b 317 markers. The number on each group ranged from 4 43 3 35, respectively. total 1868.10 cM, 2677.50 cM b....
Abstract Introduction Exercise enhances one's health and competitiveness. A strong physical fitness status can pave the way for a promising future. This study presents time-based trends in indicators—including height, weight, BMI, lung capacity, dash, long-distance running, standing long jump—among medical undergraduates during their university years. Additionally, we analyzed impact of students' on career paths. Method We conducted retrospective database by collecting test data paths...