- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Endometrial and Cervical Cancer Treatments
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Management of metastatic bone disease
- Lung Cancer Diagnosis and Treatment
- Radiation Detection and Scintillator Technologies
- Hepatocellular Carcinoma Treatment and Prognosis
- Breast Cancer Treatment Studies
- Radiation Effects and Dosimetry
- Effects of Radiation Exposure
- Radiopharmaceutical Chemistry and Applications
- Nuclear Physics and Applications
- Radiomics and Machine Learning in Medical Imaging
- Cervical Cancer and HPV Research
- Advanced MRI Techniques and Applications
- Orthopedic Infections and Treatments
- Plant Genetic and Mutation Studies
- Venous Thromboembolism Diagnosis and Management
- Advanced X-ray and CT Imaging
- Photoacoustic and Ultrasonic Imaging
- MRI in cancer diagnosis
- Head and Neck Surgical Oncology
- Technology and Security Systems
Sichuan Cancer Hospital
2013-2023
University of Electronic Science and Technology of China
2018-2023
Sichuan University
2019-2021
MedStar Washington Hospital Center
2001
Duke Medical Center
2001
The accuracy of dose calculation is crucial to the quality treatment planning and, consequently, delivered patients undergoing radiation therapy. Current general algorithms such as Pencil Beam Convolution (PBC) and Collapsed Cone (CCC) have shortcomings in regard severe inhomogeneities, particularly those regions where charged particle equilibrium does not hold. aim this study was evaluate PBC CCC lung cancer radiotherapy using Monte Carlo (MC) technology.Four plans were designed Oncentra...
Many tumor cells demonstrate hyperradiosensitivity at doses below ∼50 cGy. Together with the increased normal tissue repair under low dose rate, pulsed rate radiotherapy (PLDR), which separates a daily fractional of 200 cGy into 10 pulses 3 min interval between (∼20 cGy/pulse and effective 6.7 min−1), potentially reduces late toxicity while still providing significant control for re-irradiation treatments. This work investigates dosimetric technical feasibilities intensity modulated (IMRT)...
Abstract Postmastectomy radiation therapy is technically difficult and can be considered one of the most complex techniques concerning patient setup reproducibility. Slight variations — particularly when high‐conformal treatment are used adversely affect accuracy delivered dose outcome. This research aims to investigate inter‐fraction occurring in two different scenarios clinical practice: at reference current setups, an image‐guided system or not used, respectively. The results were with...
Pulsed low-dose-rate radiotherapy (PLDR) has been proven to be a valid method of reirradiation. Previous studies recurrent cancer were mainly based on conventional 3D CRT and VMAT delivery techniques. There are difficulties in IMRT planning using existing commercial treatment systems (TPS) meet the PLDR protocol. This work focuses ten-field TPS for two specific sites: lung cancers head neck cancers. Our protocol requires that maximum dose PTV less than 0.4 Gy mean 0.2 per field. We...
Graphical optimization (GO) and inverse planning simulated annealing (IPSA) are the main treatment techniques used in patients undergoing 3D brachytherapy treatment. This study aims to compare dosimetric difference of plans optimized by GO IPSA cervical cancer brachytherapy.21 data sets consisted computed tomography (CT) magnetic resonance imaging (MRI), acquired with Fletcher applicator situ were transferred Oncentra system. For each patient, plan was initially reach a maximal D90 tumor...
High conformal techniques such as intensity-modulated radiation therapy and volumetric-modulated arc are widely used in overloaded radiotherapy departments. In vivo dosimetric screening is essential this environment to avoid important errors. This work examines the feasibility of introducing dosimetry (IVD) checks a routine. The causes disagreements between delivered planned treatments were identified corrected during course treatment. efficiency corrections performed added workload needed...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Wang X, P, Li C, et al. An automated dose verification software for brachytherapy. Journal of Contemporary Brachytherapy. 2018;10(5):478-482. doi:10.5114/jcb.2018.79396. APA Wang, X., P., Li, C., Zhangwen, W., Chengjun, G., & J. (2018). Brachytherapy, 10(5), 478-482. https://doi.org/10.5114/jcb.2018.79396 Chicago Xianliang, Pei Churong Wu Gou Jie and Shengwei Kang 2018. "An brachytherapy". Brachytherapy 10 (5):...
Abstract Background Volumetric modulated arc therapy (VMAT) adopted in post-mastectomy radiation (PMRT) has the capacity to achieve highly conformal dose distributions. The research aims evaluate impact of positioning errors dosimetry VMAT left-sided PMRT. Methods A total 18 perturbations where introduced 11 treatment plans that shifted isocenter from its reference position 3, 5, 10 mm six directions. thoracic wall and supraclavicular clinical target volumes (CTVs), heart left lung volume...
To investigate an implementation method and the results of inverse dose optimization algorithm, Gradient Based Planning Optimization (GBPO), for three-dimensional brachytherapy.
Objective In post-mastectomy radiotherapy, high-conformal techniques are a valid method for determining the dose distribution around target. However, proximity of critical structures is reason concern. This study aims to evaluate feasibility using calibrated cone-beam computed tomography (CBCT) scans as tool timely heart evaluation. Methods A retrospective analysis was conducted on 170 CBCT 17 patients who underwent irradiation. The delivered doses that were calculated personalized compared...
Objective To simulate and calculate the dosimetric parameters of GZP 60Co source that has been clinically used in high-dose-rate brachytherapy. Methods The EGSnrc Monte Carlo software was to a well known BEBIG (Co0.A86). The results were compared with actual verify feasibility this method. A model for brachytherapy established its same way. Results For source, accorded standard. air-kerma strength per unit activity (SK/A) dose rate constant (Λ) deviated from standard by 0.2%...
Objective To investigate the Offset values of different applicators in afterloading brachytherapy. Methods Six types were selected this study which included stainless steel interstitial needle (Part#083.062), proguide round (Part#189.608), sharp (Part#189.601), vaginal multi-channel applicator (Part#110.800), fletcher CT/MR (Part#189.745) and henschke titanium (Part#110.437). According to sources imaging fluorography film, distance between first dwell position top could be measured....
Objective This study aimed to quantify the effect of dwell time deviation constraint (DTDC) on brachytherapy treatment for cervical cancer. Methods A retrospective was carried out 20 patients with radical The DTDC values changed from 0.0 1.0 by a step size 0.2. We adjusted optimization objectives ensure that all plans were optimized high-risk clinical target volume (HRCTV) D 90 (the dose 90% HRCTV) = 6 Gy, while keeping organs at risk as low possible. dose–volume histogram parameters and...
Recently, the dynamic jaw mode has been introduced in our radiation oncology center second China. Many studies showed that helical tomotherapy (HT) potential to improve organs at risk avoidance.This study aimed evaluate plan quality and efficiency of delivery compared regular HT (fixed mode) for cervical carcinoma.Plan were among fixed 2.5 cm mode, 5.0 mode. Subjects Methods A total 20 patients with carcinoma chosen compare treatment using field width) width width. The prescribed dose was...
Purpose: Recent in vitro and vivo experimental findings provided strong evidence that pulsed low‐dose‐rate radiotherapy (PLDR) produced equivalent tumor control as conventional with significantly reduced normal tissue toxicities. This work aimed to implement a PLDR clinical protocol for the management of recurrent cancers utilizing IMRT VMAT. Methods: Our requires daily 2Gy dose be delivered 0.2Gy×10 pulses 3min interval between pulses. To take advantage low‐dose hyper‐radiosensitivity mean...
Objective To study the impacts of different applicators on dose distribution in 192Ir brachytherapy. Methods The inner tubes two cylinder from Nucletron, #101.001 and#084.350, were made plastic and stainless steel, respectively. The parts them plastic, had four radiuses: 1.00 cm, 1.25 1.50 1.75 cm. EGSnrc program was used to simulate when present a phantom, results calculated by treatment planning system compared with EGSnrc. analyzed materials, thickness, numbers resident...
Objective To explore the elementary properties of LiF (Mg, Cu, and P) thermoluminescent dosimeter (TLD) in dosimetry for tumor radiotherapy, to provide a reliable basis clinical radiotherapy. Methods 60Coγ-ray 6 MV X-ray were used evaluation dispersion, repeatability, dose response TLD. To meet requirement effects energy, (50-600 cGy), radiation rate MU/min), angle incidence accelerator gantry (0°-±90°) on TLD determined respective correction factors calculated. Results The...
Objective To study the dosimetry for copper compensator in IMRT. Methods 10patients (3 nasopharyngeal carcinoma, 4 esophageal cancer, 3 colorectal cancer)from IMRT plans made Oncentra Planning System enrolled this study. The fluence matrices of each plan were converted into thickness based on attenuation coefficient under 6 MV radiation ray which was measured with ion chamber. While irradiating homogenous phantom intensity modulated performed by compensator, film used to measure...