Abstract Purpose and background The magnetic resonance (MR)‐only radiotherapy workflow is urged by the increasing use of MR image for identification delineation tumors, while a fast generation synthetic computer tomography (sCT) from dose calculation remains one key challenges to workflow. This study aimed develop neural network generate sCT in brain site evaluate dosimetry accuracy. Materials methods A generative adversarial (GAN) was developed translate T1‐weighted MRI sCT. First, "U‐net"...

Protein carbonylation refers to the covalent modification of proteins through attachment carbonyl groups, which arise from oxidative stress. This is biologically significant, as it can elicit modifications in protein functionality, signaling cascades, and cellular homeostasis. Accurate prediction sites offers valuable insights into mechanisms underlying pathogenesis related diseases. Notably, ligand interaction sites, both functional exhibit numerous similarities. The survey reveals that...

The accuracy of dose calculation is crucial to the quality treatment planning and, consequently, delivered patients undergoing radiation therapy. Current general algorithms such as Pencil Beam Convolution (PBC) and Collapsed Cone (CCC) have shortcomings in regard severe inhomogeneities, particularly those regions where charged particle equilibrium does not hold. aim this study was evaluate PBC CCC lung cancer radiotherapy using Monte Carlo (MC) technology.Four plans were designed Oncentra...

Human gut dysbiosis is associated with type 2 diabetes mellitus (T2DM); however, the microbiome in pregnant women pregestational (PGDM) remains unexplored. We investigated alterations microbiota composition or without PGDM. The was examined using 16S rRNA sequencing data of 234 maternal fecal samples that were collected during first (T1), second (T2), and third (T3) trimesters. PGDM group presented a reduction number bacteria taxonomies as pregnancies progressed. Linear discriminant analyses...

Motivated by recent advances in deep learning, the purpose of this study was to investigate a learning method automatic segment and reconstruct applicators computed tomography (CT) images for cervix brachytherapy treatment planning.U-Net model developed applicator segmentation CT images. Sixty cervical cancer patients with Fletcher were divided into training data validation according ratio 50 : 10, another 10 employed test model. Dice similarity coefficient (DSC) 95th percentile Hausdorff...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Wang X, Li J, P, Yuan K, Yin G, Wan B. Image guided radiation therapy boost in combination with high-dose-rate intracavitary brachytherapy for the treatment of cervical cancer. Journal Contemporary Brachytherapy. 2016;8(2):122-127. doi:10.5114/jcb.2016.59282. APA Wang, X., Li, J., P., Yuan, K., Yin, G., & Wan, (2016). Brachytherapy, 8(2), 122-127. https://doi.org/10.5114/jcb.2016.59282 Chicago Xianliang, Jie...

Postoperative delirium dramatically increases the mortality and morbidity of patients undergoing cardiac surgery. Preoperative education has been proven to be effective in improving recovery reducing complications. However, there is rare evidence individualized for delirium. This study aimed investigate effect preoperative personalized on postoperative surgery.A total 133 adult receiving surgery a single center were enrolled this randomized into experimental group (n=67) control (n=66), who...

The precise segmentation of organs at risk (OARs) is importance for improving therapeutic outcomes and reducing injuries patients undergoing radiotherapy. In this study, we developed a new approach accurate computed tomography (CT) image the eyes surrounding organs, which first locating then (FLTS).The FLTS was composed two steps: (a) classification CT images using convolutional neural networks (CNN), (b) modified U-shape networks. order to obtain optimal performance, enhanced our training...

Intensity modulated radiation therapy (IMRT) compensation based on 3D high-dose-rate (HDR) intracavitary brachytherapy (ICBT) boost technique (ICBT + IMRT) has been used in our hospital for advanced cervix carcinoma patients. The purpose of this study was to compare the dosimetric results four different techniques (the conventional 2D HDR [CICBT], optimized [OICBT], and IMRT-alone with applicator situ).For 30 patients locally cervical carcinoma, after completion external beam radiotherapy...

Postoperative delirium (POD) is common in elderly patients undergoing laparoscopic surgery for gastric and colorectal malignancies. POD may be affected by different fraction of inspired oxygen (FiO2). The purpose this study was to compare the effects FiO2 on POD.A randomized, double-blind controlled trial performed Qingdao Municipal Hospital Affiliated University. A total 662 aged 65 85 years old underwent isolated radical gastrectomy, resection colon cancer, or rectal cancer only. random...

Background The objective of this retrospective study was to determine whether lymph node metastasis has a prognostic impact on patients with stage IV breast cancer. Patients and methods Seven thousand three hundred seventy-nine de novo cancer diagnosed from 2004 2013 were identified. Kaplan-Meier estimate method fitted measure overall survival cancer-specific (BCSS). Cox proportional hazard analysis used evaluate the association between N BCSS after controlling variables such as other...

The cumulative dose was compared with the planned among fourteen patients undergoing image-guided, intensity-modulated radiotherapy of prostate bed. Moreover, we investigated feasibility adding tracking to routine workflow for radiotherapy.Daily cone beam computed tomography conducted image-guided radiotherapy, and weekly delivered doses were calculated tracking. Deformable image registration applied map distributions original treatment plan create a distribution. dose-volume histogram (DVH)...

Pulsed low-dose-rate radiotherapy (PLDR) has been proven to be a valid method of reirradiation. Previous studies recurrent cancer were mainly based on conventional 3D CRT and VMAT delivery techniques. There are difficulties in IMRT planning using existing commercial treatment systems (TPS) meet the PLDR protocol. This work focuses ten-field TPS for two specific sites: lung cancers head neck cancers. Our protocol requires that maximum dose PTV less than 0.4 Gy mean 0.2 per field. We...

Graphical optimization (GO) and inverse planning simulated annealing (IPSA) are the main treatment techniques used in patients undergoing 3D brachytherapy treatment. This study aims to compare dosimetric difference of plans optimized by GO IPSA cervical cancer brachytherapy.21 data sets consisted computed tomography (CT) magnetic resonance imaging (MRI), acquired with Fletcher applicator situ were transferred Oncentra system. For each patient, plan was initially reach a maximal D90 tumor...

Objectives: In breast radiotherapy, the proximity of target to sensitive structures together with uncertainty introduced by respiratory movement, make this treatment one most studied increase its effectiveness. Dosimetric and physical variables play an important role study their correlation impact on is fundamental. This retrospective aims highlight dosimetric differences 2 different clinical data sets patients receiving left-sided irradiation in free breathing (FB) or breath hold (BH)....

Abstract. Superposition of charges to pesticide spray droplets by electrostatic induction principle plays an important role in plant protection. It influences characteristics, deposition and wraparound effect on leaf surfaces. Hence, adoption optimum parameters combination will improve spraying effectiveness reduce wastage environmental pollution. This article investigated the 0-12 kV applied voltages, 2-4 bar liquid flow pressures, 20-60 cm height regimes chargeability, droplet sizes,...

Neoadjuvant Chemotherapy (NAC) followed by concurrent chemoradiotherapy (CCRT) is promising in improving the survival rate for advanced nasopharyngeal carcinoma (NPC) patients relative to CCRT alone. However, not all respond well NAC. Therefore, we aimed develop and evaluate a modified radiomics model NAC response prognosis NPC patients.A total of 165 with biopsy-proven locally were retrospectively selected from database our hospital. 85 out them training cross-validation, while other 80...