A5036565251- Congenital heart defects research
- CRISPR and Genetic Engineering
- Pluripotent Stem Cells Research
- Cellular Mechanics and Interactions
- Laser Applications in Dentistry and Medicine
- Tendon Structure and Treatment
- Extracellular vesicles in disease
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Adipokines, Inflammation, and Metabolic Diseases
- MicroRNA in disease regulation
- Adipose Tissue and Metabolism
- Exercise and Physiological Responses
University of Washington
2020
Hôpital Saint-Louis
2015-2018
Inserm
2015-2018
Assistance Publique – Hôpitaux de Paris
2015-2018
Comparative studies suggest that stem cells committed to a cardiac lineage are more effective for improving heart function than those featuring an extra-cardiac phenotype. We have therefore developed population of human embryonic cell (ESC)-derived progenitor cells. Undifferentiated ESCs (I6 line) were amplified and cardiac-committed by exposure bone morphogenetic protein-2 fibroblast growth factor receptor inhibitor. Cells responding these cardio-instructive cues express the transcription...
Polycaprolactone (PCL) is a widely used biodegradable polyester for tissue engineering applications when long-term degradation preferred. In this article, we focused on the analysis of hydrolytic virgin and bioactive poly(sodium styrene sulfonate) (pNaSS) functionalized PCL surfaces under simulated physiological conditions (phosphate buffer saline at 25 37 °C) up to 120 weeks with aim applying ligament engineering. Techniques characterize bulk surface indicated that was hydrolyzed by mode an...
Abstract In mice, exercise, cold exposure and fasting lead to the differentiation of inducible-brown adipocytes, called beige within white adipose tissue have beneficial effects on fat burning metabolism, through heat production. This browning process is associated with an increased expression key thermogenic mitochondrial uncoupling protein 1, Ucp1. Egr1 transcription factor has been described as a regulator programs, depletion spontaneous increase subcutaneous browning, in absence external...
One of the main challenges in tendon field relies understanding regulators differentiation program. The optimum culture conditions that favor cell are not identified. Mesenchymal stem cells present ability to differentiate into multiple lineages cultures under different cues ranging from chemical treatment physical constraints. We analyzed potential C3H10T1/2 cells, a murine line mesenchymal upon 2D- and 3D-culture conditions. observed cultured 2D on silicone substrate were more prone...
Abstract One of the main challenges in tendon field relies understanding regulators differentiation program. The optimum culture conditions that favor cell are not identified. Mesenchymal stem cells present ability to differentiate into multiple lineages cultures under different cues ranging from chemical treatment physical constraints. We analyzed potential C3H10T1/2 cells, a murine line mesenchymal upon 2D- and 3D-culture conditions. observed cultured 2D on silicone substrate were more...